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sarpogrelate and Albuminuria

sarpogrelate has been researched along with Albuminuria in 5 studies

sarpogrelate: structure given in first source

Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"Forty patients who had diabetes with nephropathy and arteriosclerosis obliterans and had already been treated with angiotensin II receptor blocker (n = 40) were randomly assigned to sarpogrelate (300 mg/d; n = 20) or aspirin group (100 mg/d; n = 20)."9.13Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes. ( Ishizuka, T; Ito, S; Mori, T; Nako, K; Ogawa, S, 2008)
" We then investigated the effects of 24-month treatment with sarpogrelate hydrochloride, a 5-HT(A2) receptor antagonist, on urinary albumin level in 10 type 2 diabetics with microalbuminuria, compared with not treated control group."9.10Sarpogrelate hydrochloride, a serotonin2A receptor antagonist, reduces albuminuria in diabetic patients with early-stage diabetic nephropathy. ( Haraguchi, T; Higashi, K; Kobori, S; Koga, N; Minami, J; Takahashi, T; Yano, M, 2002)
"Forty patients who had diabetes with nephropathy and arteriosclerosis obliterans and had already been treated with angiotensin II receptor blocker (n = 40) were randomly assigned to sarpogrelate (300 mg/d; n = 20) or aspirin group (100 mg/d; n = 20)."5.13Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes. ( Ishizuka, T; Ito, S; Mori, T; Nako, K; Ogawa, S, 2008)
" We then investigated the effects of 24-month treatment with sarpogrelate hydrochloride, a 5-HT(A2) receptor antagonist, on urinary albumin level in 10 type 2 diabetics with microalbuminuria, compared with not treated control group."5.10Sarpogrelate hydrochloride, a serotonin2A receptor antagonist, reduces albuminuria in diabetic patients with early-stage diabetic nephropathy. ( Haraguchi, T; Higashi, K; Kobori, S; Koga, N; Minami, J; Takahashi, T; Yano, M, 2002)
" Treatment with sarpogrelate improved ROS/NO imbalance in glomeruli, suppressed platelet aggregation in glomeruli, reduced platelet-derived microparticles, increased serum adiponectin level and reduced the level of albuminuria, compared with non-treated diabetic rats."3.74Blockade of serotonin 2A receptor improves glomerular endothelial function in rats with streptozotocin-induced diabetic nephropathy. ( Arakawa, S; Fujimoto, S; Haruna, Y; Kashihara, N; Kobayashi, S; Komai, N; Namikoshi, T; Sasaki, T; Satoh, M; Tomita, N, 2008)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, ES1
Lee, MY1
Kwon, MH1
Kim, HM1
Kang, JS1
Kim, YM1
Lee, EY1
Chung, CH1
Takahashi, T1
Yano, M1
Minami, J1
Haraguchi, T1
Koga, N1
Higashi, K1
Kobori, S1
Kobayashi, S1
Satoh, M1
Namikoshi, T1
Haruna, Y1
Fujimoto, S1
Arakawa, S1
Komai, N1
Tomita, N1
Sasaki, T1
Kashihara, N1
Ogawa, S1
Mori, T1
Nako, K1
Ishizuka, T1
Ito, S1
Ishimura, E1
Nishizawa, Y1
Emoto, M1
Shoji, T1
Inaba, M1
Kawagishi, T1
Morii, H1

Trials

3 trials available for sarpogrelate and Albuminuria

ArticleYear
Sarpogrelate hydrochloride, a serotonin2A receptor antagonist, reduces albuminuria in diabetic patients with early-stage diabetic nephropathy.
    Diabetes research and clinical practice, 2002, Volume: 58, Issue:2

    Topics: Albuminuria; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Follow-Up Studies; Glycated

2002
Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes.
    Clinical journal of the American Society of Nephrology : CJASN, 2008, Volume: 3, Issue:2

    Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Arteriosclerosis Obliterans; Aspirin; Ch

2008
Therapeutic effect of sarpogrelate, a new 5-hydroxytryptamine receptor 2A antagonist, on diabetic nephropathy and neuropathy.
    Nephron, 1997, Volume: 76, Issue:2

    Topics: Adult; Aged; Albuminuria; Diabetic Nephropathies; Diabetic Neuropathies; Female; Follow-Up Studies;

1997

Other Studies

2 other studies available for sarpogrelate and Albuminuria

ArticleYear
Sarpogrelate hydrochloride ameliorates diabetic nephropathy associated with inhibition of macrophage activity and inflammatory reaction in db/db mice.
    PloS one, 2017, Volume: 12, Issue:6

    Topics: Adiponectin; Adipose Tissue; Albuminuria; Animals; Body Weight; Cell Movement; Diabetic Nephropathie

2017
Blockade of serotonin 2A receptor improves glomerular endothelial function in rats with streptozotocin-induced diabetic nephropathy.
    Clinical and experimental nephrology, 2008, Volume: 12, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adiponectin; Albuminuria; Animals; Blood Platelets; Deoxyguanosine; Dia

2008