Page last updated: 2024-08-18

sarin and Encephalopathy, Toxic

sarin has been researched along with Encephalopathy, Toxic in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's7 (38.89)29.6817
2010's8 (44.44)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Chen, X; Cui, Y; Jin, Q; Li, L; Shi, J; Shi, M; Shi, T; Wang, C; Xu, J; Zhang, R; Zhang, Y; Zhu, S; Zong, X1
Chen, X; Cui, Y; Deng, S; Li, L; Shi, J; Shi, M; Shi, T; Song, L; Wang, C; Xu, J; Zhang, R; Zhang, Y1
Alam, SI; Bhattacharya, BK; Chaubey, K; Nagar, DP; Pant, SC; Singh, L; Srivastava, N; Waghmare, CK1
Caisberger, F; Kassa, J; Kuca, K; Misik, J; Pejchal, J; Valis, M1
Alam, SI; Bhattacharya, BK; Chaubey, K; Singh, L; Srivastava, N; Waghmare, CK1
Chapleau, M; Cool, DR; Garrett, TL; Joshi, K; Lucot, JB; Rapp, CM; Schlager, JJ1
Horova, A; Kassa, J; Matouskova, L; Musilek, K; Sepsova, V1
McDonough, JH; Shih, TM; Skovira, JW1
Garrett, TL; Grubbs, RD; Lucot, JB; Rapp, CM; Schlager, JJ1
Karasova, JZ; Kassa, J; Misik, J1
Brewer, KL; Meggs, WJ; Pekman, L; Troendle, MM1
Newmark, J1
Abou-Donia, MB1
Asukai, N; Etoh, N; Kikuchi, Y; Kumagai, N; Maekawa, K; Matsumoto, Y; Miyaki, K; Nishiwaki, Y; Ogawa, Y; Omae, K; Yoshimura, K1
Hulet, SW; McDonough, JH; Shih, TM1
Yokoyama, K1
Allon, N; Chapman, S; Grauer, E; Kadar, T; Rabinovitz, I; Raveh, L; Weissman, BA1
Cabal, J; Kassa, J1

Reviews

3 review(s) available for sarin and Encephalopathy, Toxic

ArticleYear
Therapy for nerve agent poisoning.
    Archives of neurology, 2004, Volume: 61, Issue:5

    Topics: Antidotes; Atropine; Chemical Warfare Agents; Humans; Neurotoxicity Syndromes; Neurotoxins; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Soman

2004
Organophosphorus ester-induced chronic neurotoxicity.
    Archives of environmental health, 2003, Volume: 58, Issue:8

    Topics: Acetylcholinesterase; Acute Disease; Apoptosis; Brain; Chronic Disease; Esters; Humans; Necrosis; Neurodegenerative Diseases; Neurons; Neurotoxicity Syndromes; Organophosphate Poisoning; Organophosphorus Compounds; Oxidative Stress; Prognosis; Risk Factors; Sarin

2003
Our recent experiences with sarin poisoning cases in Japan and pesticide users with references to some selected chemicals.
    Neurotoxicology, 2007, Volume: 28, Issue:2

    Topics: Agricultural Workers' Diseases; Animals; Behavior; Biotransformation; Chemical Terrorism; Chemical Warfare Agents; Cognition; DNA Damage; Humans; Japan; Malaysia; Micronuclei, Chromosome-Defective; Nervous System; Neural Conduction; Neurotoxicity Syndromes; Occupational Exposure; Organophosphorus Compounds; Oxidative Stress; Pesticides; Postural Balance; Sarin; Thiocarbamates; Time Factors

2007

Other Studies

15 other study(ies) available for sarin and Encephalopathy, Toxic

ArticleYear
Subacute sarin exposure disrupted the homeostasis of purine and pyrimidine metabolism in guinea pig striatum studied by integrated metabolomic, lipidomic and proteomic analysis.
    Toxicology letters, 2022, Aug-15, Volume: 367

    Topics: Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Guinea Pigs; Homeostasis; Lethal Dose 50; Lipidomics; Lipids; Neurotoxicity Syndromes; Proteomics; Purines; Pyrimidines; Sarin

2022
Repeated low-dose exposures to sarin disrupted the homeostasis of phospholipid and sphingolipid metabolism in guinea pig hippocampus.
    Toxicology letters, 2021, Mar-01, Volume: 338

    Topics: Acetylcholinesterase; Animals; Behavior, Animal; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Cognition; Dose-Response Relationship, Drug; Guinea Pigs; Hippocampus; Homeostasis; Lipidomics; Male; Neurotoxicity Syndromes; Phospholipids; Sarin; Spatial Learning; Sphingolipids

2021
From the Cover: Proteome Profile of Different Rat Brain Regions After Sarin Intoxication.
    Toxicological sciences : an official journal of the Society of Toxicology, 2017, Nov-01, Volume: 160, Issue:1

    Topics: Acetylcholinesterase; Animals; Blotting, Western; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Electrophoresis, Gel, Two-Dimensional; GPI-Linked Proteins; Lethal Dose 50; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurotoxicity Syndromes; Protein Interaction Maps; Proteome; Proteomics; Rats, Wistar; Reproducibility of Results; Sarin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Time Factors

2017
The benefit of combinations of oximes for the ability of antidotal treatment to counteract sarin-induced brain damage in rats.
    BMC pharmacology & toxicology, 2018, 06-28, Volume: 19, Issue:1

    Topics: Animals; Antidotes; Drug Therapy, Combination; Neurotoxicity Syndromes; Oximes; Rats, Wistar; Sarin

2018
Differential proteome analysis of rat plasma after diisopropyl fluorophosphate (DFP) intoxication, a surrogate of nerve agent sarin.
    Chemico-biological interactions, 2019, Jan-25, Volume: 298

    Topics: Animals; Blood Proteins; Cholinesterase Inhibitors; Cholinesterases; Homeostasis; Injections, Subcutaneous; Iron; Isoflurophate; Male; Nerve Agents; Neurotoxicity Syndromes; Oxidative Stress; Rats, Wistar; Reproducibility of Results; Sarin

2019
The effects of 8-OH-DPAT on neuroinflammation after sarin exposure in mice.
    Toxicology, 2013, Aug-09, Volume: 310

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apoptosis; Behavior, Animal; Brain; Cholinesterases; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Immunohistochemistry; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxicity Syndromes; Organophosphorus Compounds; Sarin; Serotonin Receptor Agonists; Survival Analysis; Weight Loss

2013
A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice.
    Toxicology mechanisms and methods, 2015, Volume: 25, Issue:3

    Topics: Acetylcholinesterase; Animals; Animals, Outbred Strains; Antidotes; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diaphragm; Dose-Response Relationship, Drug; Drug Therapy, Combination; Male; Mice; Muscarinic Antagonists; Nerve Tissue Proteins; Neurons; Neurotoxicity Syndromes; Obidoxime Chloride; Oximes; Pyridinium Compounds; Rats, Wistar; Sarin

2015
Effects of 4-pyridine aldoxime on nerve agent-inhibited acetylcholinesterase activity in guinea pigs.
    Archives of toxicology, 2009, Volume: 83, Issue:12

    Topics: Acetylcholinesterase; Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Longevity; Male; Neurotoxicity Syndromes; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Salivation; Sarin; Seizures; Tears

2009
A murine model for sarin exposure using the carboxylesterase inhibitor CBDP.
    Neurotoxicology, 2010, Volume: 31, Issue:5

    Topics: Acetylcholinesterase; Animals; Carboxylesterase; Chemical Warfare Agents; Cholinesterases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Glial Fibrillary Acidic Protein; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neuroglia; Neurotoxicity Syndromes; Organophosphorus Compounds; Sarin; Seizures; Time Factors

2010
A comparison of the potency of a novel bispyridinium oxime K203 and currently available oximes (obidoxime, HI-6) to counteract the acute neurotoxicity of sarin in rats.
    Basic & clinical pharmacology & toxicology, 2012, Volume: 111, Issue:5

    Topics: Animals; Antidotes; Atropine; Autonomic Nervous System; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Czech Republic; Drug Therapy, Combination; Lethal Dose 50; Male; Muscarinic Antagonists; Neurons; Neurotoxicity Syndromes; Obidoxime Chloride; Oximes; Psychomotor Performance; Pyridinium Compounds; Rats; Rats, Wistar; Sarin

2012
Naltrexone prevents delayed encephalopathy in rats poisoned with the sarin analogue diisopropylflurophosphate.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:4

    Topics: Animals; Brain Diseases; Central Nervous System Agents; Cholinesterase Inhibitors; Female; Injections, Intraperitoneal; Isoflurophate; Learning; Memory; Naltrexone; Neurotoxicity Syndromes; Rats; Rats, Long-Evans; Sarin

2013
Effects of sarin on the nervous system of subway workers seven years after the Tokyo subway sarin attack.
    Journal of occupational health, 2005, Volume: 47, Issue:4

    Topics: Adult; Cholinesterase Inhibitors; Cross-Sectional Studies; Follow-Up Studies; Humans; Middle Aged; Nervous System; Neurotoxicity Syndromes; Occupational Exposure; Railroads; Sarin; Tokyo

2005
The effects of repeated low-dose sarin exposure.
    Toxicology and applied pharmacology, 2006, Sep-01, Volume: 215, Issue:2

    Topics: Acetylcholinesterase; Animals; Behavior, Animal; Body Weight; Chemical Warfare Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electroencephalography; Erythrocytes; Gait; Guinea Pigs; Injections, Subcutaneous; Lethal Dose 50; Longevity; Male; Nervous System; Neurotoxicity Syndromes; Sarin; Seizures; Sleep Stages

2006
Single whole-body exposure to sarin vapor in rats: long-term neuronal and behavioral deficits.
    Toxicology and applied pharmacology, 2008, Mar-01, Volume: 227, Issue:2

    Topics: Administration, Inhalation; Animals; Brain; Brain Chemistry; Cell Death; Chemical Warfare Agents; Cholinesterase Inhibitors; Cognition; Dinoprostone; Gases; Lethal Dose 50; Male; Maze Learning; Memory, Short-Term; Neurons; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Muscarinic; Sarin

2008
A comparison of the efficacy of a new asymmetric bispyridinium oxime BI-6 with presently used oximes and H oximes against sarin by in vitro and in vivo methods.
    Human & experimental toxicology, 1999, Volume: 18, Issue:9

    Topics: Animals; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diaphragm; Dose-Response Relationship, Drug; Drug Antagonism; Lethal Dose 50; Male; Neurotoxicity Syndromes; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Sarin

1999