sarin has been researched along with Disease Models, Animal in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 5 (35.71) | 2.80 |
| Authors | Studies |
|---|---|
| Ardinger, CE; Berger, KE; Dunn, EN; Haines, KM; Jackson Piercy, CE; Lee-Stubbs, RB; Matson, LM; McCarren, HS; McDonough, JH; Miller-Smith, SM; Whitten, KA | 1 |
| Capacio, BR; Koplovitz, I; Oyler, BL; Shih, TM | 1 |
| Acon-Chen, C; Loughery, TN; Shih, TM; Whitten, KA | 1 |
| Baranes, S; Chapman, S; David, T; Dekel Jaoui, H; Efrati, R; Egoz, I; Gez, R; Gore, A; Grauer, E; Lazar, S; Neufeld-Cohen, A; Yampolsky, M | 1 |
| Andrýs, R; Karasová, JŽ; Kassa, J; Klusoňová, A; Lísa, M | 1 |
| Bird, M; Green, AC; Kassa, J; Tattersall, JEH; Timperley, CM; Williams, RL | 1 |
| McDonough, JH; Shih, TM; Skovira, JW | 1 |
| Garrett, TL; Grubbs, RD; Lucot, JB; Rapp, CM; Schlager, JJ | 1 |
| Barr, EB; Conn, CA; Dokladny, K; Henderson, RF; Kluger, MJ; Kozak, A; Kozak, W; Ménache, MG; Rudolph, K; Wachulec, M | 1 |
| Barr, EB; Blackwell, WB; Clark, CR; Conn, CA; Dokladny, K; Henderson, RF; Kalra, R; Kluger, MJ; Kozak, A; Kozak, W; Langley, RJ; March, TH; Mash, DC; Ménache, MG; Razani-Boroujerdi, S; Rudolph, K; Singh, SP; Sopori, ML; Tesfaigzi, Y; Wachulec, M | 1 |
| Abraham, S; Cohen, G; Dachir, S; Gilat, E; Herskovitz, M; Kapon, J; Levy, A; Raveh, L; Teitelbaum, Z | 1 |
| Dubovický, M; Grubbs, RD; Lucot, JB; Mach, M; Nagaoka, M; Price, WA | 1 |
| Grauer, E; Levy, A | 1 |
| McDonough, JH; Shih, TM | 1 |
14 other study(ies) available for sarin and Disease Models, Animal
| Article | Year |
|---|---|
Evaluation of fosphenytoin, levetiracetam, and propofol as treatments for nerve agent-induced seizures in pediatric and adult rats.
Topics: Age Factors; Animals; Anticonvulsants; Brain; Disease Models, Animal; Female; Levetiracetam; Male; Organothiophosphorus Compounds; Phenytoin; Propofol; Rats, Sprague-Dawley; Sarin; Sex Factors; Status Epilepticus | 2020 |
The tertiary oxime monoisonitrosoacetone penetrates the brain, reactivates inhibited acetylcholinesterase, and reduces mortality and morbidity following lethal sarin intoxication in guinea pigs.
Topics: Acetylcholinesterase; Animals; Antidotes; Brain; Cholinesterase Reactivators; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Guinea Pigs; Male; Microdialysis; Organophosphate Poisoning; Oximes; Permeability; Pralidoxime Compounds; Sarin; Tissue Distribution | 2021 |
Intramuscularly administered A1 adenosine receptor agonists as delayed treatment for organophosphorus nerve agent-induced Status Epilepticus.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Anticonvulsants; Brain; Deoxyadenosines; Disease Models, Animal; Drug Administration Schedule; Injections, Intramuscular; Male; Neuroprotective Agents; Norbornanes; Rats, Sprague-Dawley; Sarin; Soman; Status Epilepticus; Time Factors | 2021 |
Neuroprotection by delayed triple therapy following sarin nerve agent insult in the rat.
Topics: Animals; Anticonvulsants; Behavior, Animal; Brain; Carrier Proteins; Dinoprostone; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Injections, Intramuscular; Injections, Intraperitoneal; Ketamine; Male; Midazolam; Open Field Test; Rats, Sprague-Dawley; Receptors, GABA-A; Recognition, Psychology; Sarin; Status Epilepticus; Time Factors; Valproic Acid | 2021 |
Effect of Oxime Encapsulation on Acetylcholinesterase Reactivation: Pharmacokinetic Study of the Asoxime-Cucurbit[7]uril Complex in Mice Using Hydrophilic Interaction Liquid Chromatography-Mass Spectrometry.
Topics: Acetylcholinesterase; Animals; Area Under Curve; Blood-Brain Barrier; Bridged-Ring Compounds; Cholinesterase Inhibitors; Cholinesterase Reactivators; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Carriers; Enzyme Assays; Humans; Hydrophobic and Hydrophilic Interactions; Imidazoles; Mass Spectrometry; Mice; Organophosphate Poisoning; Oximes; Pyridinium Compounds; Sarin | 2021 |
Some benefit from non-oximes MB408, MB442 and MB444 in combination with the oximes HI-6 or obidoxime and atropine in antidoting sarin or cyclosarin poisoned mice.
Topics: Animals; Atropine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Lethal Dose 50; Male; Mice; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Sarin; Time Factors | 2018 |
Protection against sarin-induced seizures in rats by direct brain microinjection of scopolamine, midazolam or MK-801.
Topics: Amygdala; Animals; Anticonvulsants; Brain; Cholinergic Antagonists; Cholinesterase Inhibitors; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acid Antagonists; GABA Modulators; Injections, Intraventricular; Male; Midazolam; Olfactory Pathways; Rats; Rats, Sprague-Dawley; Sarin; Scopolamine; Seizures; Treatment Outcome | 2010 |
A murine model for sarin exposure using the carboxylesterase inhibitor CBDP.
Topics: Acetylcholinesterase; Animals; Carboxylesterase; Chemical Warfare Agents; Cholinesterases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Glial Fibrillary Acidic Protein; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neuroglia; Neurotoxicity Syndromes; Organophosphorus Compounds; Sarin; Seizures; Time Factors | 2010 |
Effects of sarin on temperature and activity of rats as a model for gulf war syndrome neuroregulatory functions.
Topics: Animals; Body Temperature; Chemical Warfare Agents; Cholinesterase Inhibitors; Disease Models, Animal; Male; Motor Activity; Persian Gulf Syndrome; Rats; Rats, Inbred F344; Sarin | 2002 |
Response of F344 rats to inhalation of subclinical levels of sarin: exploring potential causes of Gulf War illness.
Topics: Animals; Autoradiography; Brain; Chemical Warfare Agents; Cognition Disorders; Disease Models, Animal; Immune System; Inhalation Exposure; Memory Disorders; Persian Gulf Syndrome; Rats; Rats, Inbred F344; Receptors, Cholinergic; Sarin | 2001 |
Extrapolating from animal studies to the efficacy in humans of a pretreatment combination against organophosphate poisoning.
Topics: Animals; Chemical Warfare Agents; Cholinergic Antagonists; Cyclopentanes; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Infusions, Parenteral; Lethal Dose 50; Male; Metabolic Clearance Rate; Organophosphate Poisoning; Organophosphates; Papio anubis; Poisoning; Pyridostigmine Bromide; Sarin; Species Specificity; Treatment Outcome | 2007 |
Delayed behavioral and endocrine effects of sarin and stress exposure in mice.
Topics: Acoustic Stimulation; Adrenal Glands; Animals; Behavior, Animal; Catecholamines; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterases; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Lethal Dose 50; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neural Inhibition; Persian Gulf Syndrome; Reflex, Startle; Sarin; Stress, Psychological; Time Factors | 2008 |
Oxotremorine-induced hypothermia as a method for evaluating long-term neuronal changes following poisoning by cholinesterase inhibitors in rats.
Topics: Aldicarb; Animals; Body Temperature; Carbamates; Central Nervous System; Cholinesterase Inhibitors; Disease Models, Animal; Hypothermia; Lethal Dose 50; Male; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Organophosphorus Compounds; Organothiophosphorus Compounds; Oxotremorine; Peripheral Nervous System; Rats; Rats, Sprague-Dawley; Recovery of Function; Reproducibility of Results; Sarin; Seizures; Time Factors; Toxicity Tests | 2007 |
Efficacy of biperiden and atropine as anticonvulsant treatment for organophosphorus nerve agent intoxication.
Topics: Animals; Anticonvulsants; Atropine; Biperiden; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Seizures; Soman | 2000 |