sarin has been researched along with Absence Seizure in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (11.11) | 18.7374 |
| 1990's | 3 (8.33) | 18.2507 |
| 2000's | 12 (33.33) | 29.6817 |
| 2010's | 17 (47.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bealer, SL; Dudek, FE; Ekstrand, JJ; Lehmkuhle, MJ; McDonough, JH; Miller-Smith, SM; Scholl, EA | 1 |
| Chapman, S; Egoz, I; Gez, R; Grauer, E; Lazar, S | 1 |
| Ardinger, C; Dunn, E; Haines, K; Lee-Stubbs, R; Matson, L; McCarren, H; McDonough, J; Miller-Smith, S; Whitten, K | 1 |
| Dabisch, PA; Doctor, BP; Hastings, NB; Hulet, SW; Jakubowski, EM; Mioduszewski, RJ; Saxena, A; Sun, W | 2 |
| Płusa, T; Sokołowski, R | 1 |
| McDonough, JH; O'Donnell, JC; Shih, TM; Skovira, JW | 1 |
| McDonough, JH; Shih, TM; Skovira, JW | 2 |
| McDonough, JH; O'Donnell, JC; Shih, TM | 2 |
| Garrett, TL; Grubbs, RD; Lucot, JB; Rapp, CM; Schlager, JJ | 1 |
| Guarisco, JA; Kan, RK; McDonough, JH; Myers, TM; Shih, TM | 1 |
| Chanda, S; Che, MM; Doctor, BP; Nambiar, MP; Perkins, MW; Rezk, PE; Sabnekar, P; Sciuto, AM; Song, J | 1 |
| Dillman, JF; Lumley, LA; Meyerhoff, JL; Robison, CL; Spradling, KD | 2 |
| Bloch-Shilderman, E; Brandeis, R; Egoz, I; Grauer, E; Katalan, S; Lazar, S; Rabinovitz, I; Raveh, L | 1 |
| Chambers, HW; Chambers, JE; Meek, EC; Pringle, RB | 1 |
| Alkalai, D; Amitai, G; Brandeis, R; Cohen, G; Eshel, G; Gilat, E; Goldman, M; Lahat, E; Levy, A; Rabinovitz, I | 1 |
| Breton, P; Buée, J; Calvet, JH; Christin, D; Delamanche, S; Taysse, L | 1 |
| Bueters, TJ; Harrison, PK; Ijzerman, AP; Tattersall, JE; van Helden, HP | 1 |
| Bajgar, J; Bartosova-Sevelova, L | 1 |
| Brandeis, R; Cohen, G; Gilat, E; Kadar, T; Kapon, Y; Levy, A; Rabinovitz, I; Sahar, R | 1 |
| Chapman, S; Gilat, E; Kadar, T | 1 |
| Hulet, SW; McDonough, JH; Shih, TM | 1 |
| Kellar, KJ | 1 |
| Grauer, E; Levy, A | 1 |
| Alkalay, D; Cohen, G; Kadar, T; Raveh, L; Sahar, R; Shapira, S | 1 |
| Belkin, M; Solberg, Y | 1 |
| McDonough, JH; Shih, TM | 1 |
| Bajgar, J; Herink, J; Kassa, J; Koupilová, M; Krocová, Z; Pecka, M; Tichý, M | 1 |
| Burchfiel, JL; Duffy, FH; Van Sim, M | 1 |
| Bajgar, J | 1 |
| Graham, JS; Jaax, NK; McLeod, CG; Singer, AW | 1 |
| Dulaney, MD; Fernando, JC; Ho, IK; Hoskins, B; Lim, DK; Liu, DD; Watanabe, HK | 1 |
| Fernando, JC; Ho, IK; Hoskins, B; Lim, DK | 1 |
2 review(s) available for sarin and Absence Seizure
| Article | Year |
|---|---|
[Today's threat of use of organophosphorus compounds].
Topics: Chemical Warfare Agents; Cholinesterase Inhibitors; Environmental Exposure; Humans; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Seizures; Soman | 2015 |
The role of excitotoxicity in organophosphorous nerve agents central poisoning.
Topics: Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Convulsants; Excitatory Amino Acid Antagonists; Humans; Neurons; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Receptors, N-Methyl-D-Aspartate; Sarin; Seizures; Soman; Synaptic Transmission | 1997 |
34 other study(ies) available for sarin and Absence Seizure
| Article | Year |
|---|---|
Age-dependent behaviors, seizure severity and neuronal damage in response to nerve agents or the organophosphate DFP in immature and adult rats.
Topics: Animals; Behavior, Animal; Brain; Female; Isoflurophate; Male; Nerve Agents; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Seizures | 2018 |
Time dependent dual effect of anti-inflammatory treatments on sarin-induced brain inflammation: Suggested role of prostaglandins.
Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Atropine; Brain Diseases; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dinoprostone; Encephalitis; Male; Midazolam; Nerve Agents; Neuroprotective Agents; Prostaglandins; Rats; Rats, Sprague-Dawley; Sarin; Seizures; Trimedoxime | 2019 |
Evaluation of first-line anticonvulsants to treat nerve agent-induced seizures and prevent neuropathology in adult and pediatric rats.
Topics: Aging; Animals; Animals, Newborn; Anticonvulsants; Diazepam; Dose-Response Relationship, Drug; Electrocorticography; Female; Male; Midazolam; Nerve Agents; Nervous System Diseases; Neuroprotective Agents; Organothiophosphorus Compounds; Pregnancy; Rats; Rats, Sprague-Dawley; Sarin; Seizures; Status Epilepticus | 2019 |
Prophylaxis with human serum butyrylcholinesterase protects Göttingen minipigs exposed to a lethal high-dose of sarin vapor.
Topics: Acetylcholinesterase; Animals; Blood Chemical Analysis; Butyrylcholinesterase; Chemical Warfare Agents; Electrocardiography; Electroencephalography; Gases; Humans; Male; Miosis; Respiratory Insufficiency; Sarin; Seizures; Swine; Swine, Miniature | 2015 |
Treatment with tertiary oximes prevents seizures and improves survival following sarin intoxication.
Topics: Acetylcholinesterase; Animals; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diacetyl; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Guinea Pigs; Injections, Intramuscular; Male; Muscarinic Antagonists; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Sarin; Seizures; Treatment Outcome; Up-Regulation | 2010 |
Protection against sarin-induced seizures in rats by direct brain microinjection of scopolamine, midazolam or MK-801.
Topics: Amygdala; Animals; Anticonvulsants; Brain; Cholinergic Antagonists; Cholinesterase Inhibitors; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acid Antagonists; GABA Modulators; Injections, Intraventricular; Male; Midazolam; Olfactory Pathways; Rats; Rats, Sprague-Dawley; Sarin; Scopolamine; Seizures; Treatment Outcome | 2010 |
Effects of 4-pyridine aldoxime on nerve agent-inhibited acetylcholinesterase activity in guinea pigs.
Topics: Acetylcholinesterase; Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Longevity; Male; Neurotoxicity Syndromes; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Salivation; Sarin; Seizures; Tears | 2009 |
Changes in extracellular striatal acetylcholine and brain seizure activity following acute exposure to nerve agents in freely moving guinea pigs.
Topics: Acetylcholine; Animals; Brain; Chemical Warfare Agents; Choline; Cholinesterase Inhibitors; Corpus Striatum; Electroencephalography; Guinea Pigs; Male; Organothiophosphorus Compounds; Sarin; Seizures; Soman | 2010 |
A murine model for sarin exposure using the carboxylesterase inhibitor CBDP.
Topics: Acetylcholinesterase; Animals; Carboxylesterase; Chemical Warfare Agents; Cholinesterases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Glial Fibrillary Acidic Protein; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neuroglia; Neurotoxicity Syndromes; Organophosphorus Compounds; Sarin; Seizures; Time Factors | 2010 |
The oxime pro-2-PAM provides minimal protection against the CNS effects of the nerve agents sarin, cyclosarin, and VX in guinea pigs.
Topics: Animals; Cholinesterase Reactivators; Guinea Pigs; Male; Organophosphorus Compounds; Organothiophosphorus Compounds; Pralidoxime Compounds; Prodrugs; Sarin; Seizures | 2011 |
Aerosolized scopolamine protects against microinstillation inhalation toxicity to sarin in guinea pigs.
Topics: Aerosols; Animals; Antidotes; Behavior, Animal; Chemical Warfare Agents; Cholinergic Antagonists; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Guinea Pigs; Heart Rate; Inhalation Exposure; Male; Oxygen; Protective Agents; Respiratory Mucosa; Sarin; Scopolamine; Seizures; Survival Analysis; Tremor; Weight Loss | 2011 |
In vivo microdialysis and electroencephalographic activity in freely moving guinea pigs exposed to organophosphorus nerve agents sarin and VX: analysis of acetylcholine and glutamate.
Topics: Acetylcholine; Animals; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Electroencephalography; Glutamic Acid; Guinea Pigs; Male; Microdialysis; Multivariate Analysis; Organothiophosphorus Compounds; Sarin; Seizures; Severity of Illness Index | 2011 |
Transcriptional analysis of rat piriform cortex following exposure to the organophosphonate anticholinesterase sarin and induction of seizures.
Topics: Animals; Anticonvulsants; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Humans; Male; Microarray Analysis; Muscarinic Antagonists; Pralidoxime Compounds; Principal Component Analysis; Rats; Rats, Sprague-Dawley; Sarin; Seizures; Signal Transduction; Transcription, Genetic | 2011 |
Transcriptional responses of the nerve agent-sensitive brain regions amygdala, hippocampus, piriform cortex, septum, and thalamus following exposure to the organophosphonate anticholinesterase sarin.
Topics: Amygdala; Animals; Anticonvulsants; Atropine; Cerebral Cortex; Chemical Warfare Agents; Cholinesterase Inhibitors; Diazepam; Gene Expression Profiling; Gene Regulatory Networks; Hippocampus; Interleukin-1beta; Interleukin-6; Male; Microarray Analysis; Muscarinic Antagonists; Oximes; Principal Component Analysis; Pyridines; Rats; Rats, Sprague-Dawley; Sarin; Seizures; Septum of Brain; Thalamus; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2011 |
Pretreatment with human serum butyrylcholinesterase alone prevents cardiac abnormalities, seizures, and death in Göttingen minipigs exposed to sarin vapor.
Topics: Acetylcholinesterase; Animals; Arrhythmias, Cardiac; Butyrylcholinesterase; Chemical Warfare Agents; Dose-Response Relationship, Drug; Humans; Male; Respiratory Insufficiency; Sarin; Seizures; Swine; Swine, Miniature | 2011 |
Magnesium sulfate treatment against sarin poisoning: dissociation between overt convulsions and recorded cortical seizure activity.
Topics: Animals; Anticonvulsants; Antidotes; Brain Injuries; Cerebral Cortex; Chemical Warfare Agents; Cyclopentanes; Epilepsy, Tonic-Clonic; Magnesium Sulfate; Male; Midazolam; Rats; Rats, Sprague-Dawley; Sarin; Seizures; Telemetry | 2013 |
Testing of novel brain-penetrating oxime reactivators of acetylcholinesterase inhibited by nerve agent surrogates.
Topics: Acetylcholinesterase; Animals; Blood-Brain Barrier; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Evaluation, Preclinical; GPI-Linked Proteins; Male; Organophosphates; Organothiophosphorus Compounds; Oximes; Rats; Rats, Sprague-Dawley; Sarin; Seizures | 2013 |
Nasal midazolam as a novel anticonvulsive treatment against organophosphate-induced seizure activity in the guinea pig.
Topics: Administration, Intranasal; Animals; Anticonvulsants; Cholinesterase Inhibitors; Electrophysiology; GABA Agonists; Guinea Pigs; Injections, Intramuscular; Midazolam; Organophosphorus Compounds; Sarin; Seizures; Time Factors | 2003 |
Comparative efficacy of diazepam and avizafone against sarin-induced neuropathology and respiratory failure in guinea pigs: influence of atropine dose.
Topics: Animals; Anticonvulsants; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Diazepam; Dipeptides; Drug Interactions; Electroencephalography; Guinea Pigs; Histocytochemistry; Muscarinic Antagonists; Nervous System Diseases; Pralidoxime Compounds; Prodrugs; Pyridostigmine Bromide; Respiratory Insufficiency; Sarin; Seizures | 2003 |
Partial adenosine A(1) receptor agonists inhibit sarin-induced epileptiform activity in the hippocampal slice.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Deoxyadenosines; Guinea Pigs; Hippocampus; Male; Microelectrodes; Neurons; Receptor, Adenosine A1; Sarin; Seizures; Soman; Structure-Activity Relationship; Xanthines | 2003 |
Changes of acetylcholinesterase activity after long-term exposure to sarin vapors in rats.
Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; Inhalation Exposure; Rats; Rats, Wistar; Sarin; Seizures; Sialorrhea | 2005 |
Anticonvulsant treatment of sarin-induced seizures with nasal midazolam: an electrographic, behavioral, and histological study in freely moving rats.
Topics: Administration, Intranasal; Animals; Anticonvulsants; Behavior, Animal; Body Weight; Brain; Cholinesterase Inhibitors; Electrodes, Implanted; Electroencephalography; Hypnotics and Sedatives; Male; Maze Learning; Midazolam; Muscarinic Antagonists; Rats; Rats, Sprague-Dawley; Sarin; Scopolamine; Seizures; Transfer, Psychology | 2005 |
Seizure duration following sarin exposure affects neuro-inflammatory markers in the rat brain.
Topics: Animals; Anticonvulsants; Brain Chemistry; Chemical Warfare Agents; Cholinesterase Inhibitors; Cytokines; Dinoprostone; Electroencephalography; Electrophysiology; Hippocampus; Inflammation; Interleukin-1; Interleukin-6; Male; Midazolam; Rats; Rats, Sprague-Dawley; Sarin; Seizures; Tumor Necrosis Factor-alpha | 2006 |
The effects of repeated low-dose sarin exposure.
Topics: Acetylcholinesterase; Animals; Behavior, Animal; Body Weight; Chemical Warfare Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electroencephalography; Erythrocytes; Gait; Guinea Pigs; Injections, Subcutaneous; Lethal Dose 50; Longevity; Male; Nervous System; Neurotoxicity Syndromes; Sarin; Seizures; Sleep Stages | 2006 |
Overcoming inhibitions.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Benzodiazepines; Blood-Brain Barrier; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Drug Therapy, Combination; Galantamine; Guinea Pigs; Insecticides; Neurons; Neurotransmitter Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Paraoxon; Pralidoxime Compounds; Pyridostigmine Bromide; Receptors, Cholinergic; Receptors, Muscarinic; Sarin; Seizures; Soman; Time Factors | 2006 |
Oxotremorine-induced hypothermia as a method for evaluating long-term neuronal changes following poisoning by cholinesterase inhibitors in rats.
Topics: Aldicarb; Animals; Body Temperature; Carbamates; Central Nervous System; Cholinesterase Inhibitors; Disease Models, Animal; Hypothermia; Lethal Dose 50; Male; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Organophosphorus Compounds; Organothiophosphorus Compounds; Oxotremorine; Peripheral Nervous System; Rats; Rats, Sprague-Dawley; Recovery of Function; Reproducibility of Results; Sarin; Seizures; Time Factors; Toxicity Tests | 2007 |
Sarin-induced neuropathology in rats.
Topics: Animals; Brain; Brain Diseases; Male; Rats; Rats, Sprague-Dawley; Sarin; Seizures; Soman | 1995 |
Efficacy of biperiden and atropine as anticonvulsant treatment for organophosphorus nerve agent intoxication.
Topics: Animals; Anticonvulsants; Atropine; Biperiden; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Seizures; Soman | 2000 |
Toxic effects of sarin in rats at three months following single or repeated low-level inhalation exposure.
Topics: Administration, Inhalation; Animals; Behavior, Animal; Biomarkers; Central Nervous System Diseases; Cholinesterase Inhibitors; Clinical Chemistry Tests; Hematologic Tests; Immune System; Inhalation Exposure; Lymphocyte Activation; Lymphocytes; Macrophages, Peritoneal; Male; Rats; Rats, Wistar; Sarin; Seizures; Toxicity Tests | 2001 |
Persistent effects of sarin and dieldrin upon the primate electroencephalogram.
Topics: Animals; Dieldrin; Electrodes, Implanted; Electroencephalography; Female; Haplorhini; Macaca mulatta; Male; Organophosphorus Compounds; Sarin; Seizures; Time Factors; Wakefulness | 1976 |
Biological monitoring of exposure to nerve agents.
Topics: Acetylcholinesterase; Animals; Brain; Diaphragm; Dogs; Organophosphorus Compounds; Organothiophosphorus Compounds; Rats; Salivation; Sarin; Seizures; Soman | 1992 |
Cardiomyopathy in Soman and Sarin intoxicated rats.
Topics: Animals; Brain; Heart; Male; Myocardium; Necrosis; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Sarin; Seizures; Soman | 1987 |
Relationship between the neurotoxicities of Soman, Sarin and Tabun, and acetylcholinesterase inhibition.
Topics: Animals; Cholinesterase Inhibitors; Corpus Striatum; Injections, Subcutaneous; Male; Mastication; Organophosphates; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Sarin; Seizures; Soman; Tremor | 1986 |
Variability of neurotoxicity of and lack of tolerance to the anticholinesterases soman and sarin in the rat.
Topics: Animals; Body Temperature; Cholinesterase Inhibitors; Drug Tolerance; Male; Nervous System; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Sarin; Seizures; Soman; Tremor | 1985 |