Page last updated: 2024-10-20

sarcosine and Cancer of Prostate

sarcosine has been researched along with Cancer of Prostate in 73 studies

cocobetaine: N-alkyl-betaine; cause of shampoo dermatitis

Research Excerpts

ExcerptRelevanceReference
"Plasma sarcosine was measured using gas chromatography-mass spectrometry (GC-MS) in adults classified as noncancerous controls (with benign prostate hyperplasia [BPH], n = 36), with prostatic intraepithelial neoplasia (PIN, n = 16), or with PCa (n = 27)."7.96Plasma Sarcosine Measured by Gas Chromatography-Mass Spectrometry Distinguishes Prostatic Intraepithelial Neoplasia and Prostate Cancer from Benign Prostate Hyperplasia. ( Appolonova, SA; Brito, A; Enikeev, DV; Fodor, M; Lartsova, EV; Lerner, YV; Lyundup, AV; Markin, PA; Mikhajlov, VY; Moskaleva, N; Potoldykova, NV; Shpot, YV, 2020)
"Plasma sarcosine was measured using gas chromatography-mass spectrometry (GC-MS) in adults classified as noncancerous controls (with benign prostate hyperplasia [BPH], n = 36), with prostatic intraepithelial neoplasia (PIN, n = 16), or with PCa (n = 27)."3.96Plasma Sarcosine Measured by Gas Chromatography-Mass Spectrometry Distinguishes Prostatic Intraepithelial Neoplasia and Prostate Cancer from Benign Prostate Hyperplasia. ( Appolonova, SA; Brito, A; Enikeev, DV; Fodor, M; Lartsova, EV; Lerner, YV; Lyundup, AV; Markin, PA; Mikhajlov, VY; Moskaleva, N; Potoldykova, NV; Shpot, YV, 2020)
"Prostate cancer is the leading cause of cancer in men, and its incidence increases with age."2.82Dual contribution of the mTOR pathway and of the metabolism of amino acids in prostate cancer. ( Juárez-López, D; Schcolnik-Cabrera, A, 2022)
"Biomarkers can improve prostate cancer diagnosis and treatment."2.53Biomarkers in localized prostate cancer. ( Autorino, R; Bottero, D; Buonerba, C; Coman, I; Cosimato, V; De Cobelli, O; De Placido, S; Deliu, VM; Di Lorenzo, G; Ditonno, P; Ferro, M; Lucarelli, G; Perdonà, S; Terracciano, D, 2016)
"Prostate cancer is usually a disease of elderly men, however, over 40 years of age the tumor can appear at any times."2.50[New challenges and earlier approved methods in the laboratory diagnosis of prostate cancer]. ( Kovács, GL, 2014)
"Early diagnosis of cancer of the prostate is very important, because the sooner the cancer is detected, the better it is treated."2.49Sarcosine as a potential prostate cancer biomarker--a review. ( Adam, V; Babula, P; Cernei, N; Eckschlager, T; Gumulec, J; Heger, Z; Kizek, R; Masarik, M; Stiborova, M; Zitka, O, 2013)
"Prostate cancer is the most prevalent cancer in the Western male population and the second leading cause of cancer death in men, affecting over 10 million individuals."2.46Novel biomarkers and therapeutic targets for prostate cancer. ( Naz, RK; Williams, RM, 2010)
"Riboflavin was employed to mimic the active center of the enzyme sarcosine oxidase for constructing the biomimetic sensor."1.51An electrochemical sarcosine sensor based on biomimetic recognition. ( Chen, J; Fu, B; Li, K; Liu, T, 2019)
"Sarcosine is a widely discussed oncometabolite of prostate cells."1.48Sarcosine influences apoptosis and growth of prostate cells via cell-type specific regulation of distinct sets of genes. ( Adam, V; Buchtelova, H; Eckschlager, T; Heger, Z; Horackova, E; Michalek, P; Rodrigo, MAM; Stiborova, M; Strmiska, V, 2018)
"Post-treatment sarcosine levels were elevated in 266 (52%) patients and highly elevated (≥200 nmol/L) in 71 (13%) patients."1.48Post-treatment urinary sarcosine as a predictor of recurrent relapses in patients with prostate cancer. ( Adam, V; Cernei, N; Gumulec, J; Heger, Z; Lackova, Z; Pacik, D; Plevova, M; Raudenska, M; Sorokac-Kubolkova, A; Strmiska, V; Zitka, O, 2018)
"Prostate cancer is one of the most widespread types of tumor diseases in men."1.42On-line determination of sarcosine in biological fluids utilizing dummy molecularly imprinted polymers in microextraction by packed sorbent. ( Abdel-Rehim, A; Abdel-Rehim, M; Moein, MM, 2015)
"On this effort, prostate cancer antigen 3 (PCA3), prostate health index (phi) and sarcosine have been presented as promising tools."1.42Improving the prediction of pathologic outcomes in patients undergoing radical prostatectomy: the value of prostate cancer antigen 3 (PCA3), prostate health index (phi) and sarcosine. ( Bottero, D; Bruzzese, D; Cosimato, V; De Cobelli, O; Ferro, M; Giorgio, E; Lucarelli, G; Marino, A; Mazzarella, C; Perdonà, S; Perruolo, G; Tagliamonte, V; Terracciano, D, 2015)
"Monitoring Prostate Cancer (PCa) biomarkers is an efficient way to diagnosis this disease early, since it improves the therapeutic success rate and suppresses PCa patient mortality: for this reason a powerful analytical technique such as electrochemiluminescence (ECL) is already used for this application, but its widespread usability is still hampered by the high cost of commercial ECL equipment."1.42An electrochemiluminescence-supramolecular approach to sarcosine detection for early diagnosis of prostate cancer. ( Bertani, F; Biavardi, E; Dalcanale, E; Fracasso, G; Marcaccio, M; Paolucci, F; Prodi, L; Ramarli, D; Rampazzo, E; Valenti, G; Villani, E, 2015)
"Sarcosine has been investigated as a prostate cancer biomarker with mixed results concerning its predictive power."1.42A case control study of sarcosine as an early prostate cancer detection biomarker. ( Ankerst, DP; Hoefler, J; Leach, RJ; Liss, M; Thompson, IM; Zapata, D, 2015)
"Sarcosine, a potential biomarker of prostate cancer, has drawn great attention in recent years."1.40Sensitive determination of the potential biomarker sarcosine for prostate cancer by LC-MS with N,N'-dicyclohexylcarbodiimide derivatization. ( Chen, J; Chen, Z; Zhang, J; Zhang, W, 2014)
"As the prostate cancer (PCa) progresses, sarcosine levels increase both in tumor cells and urine samples, suggesting that this metabolite measurements can help in the creation of non-invasive diagnostic methods for this disease."1.40Sarcosine oxidase composite screen-printed electrode for sarcosine determination in biological samples. ( Costa-Rodrigues, J; Fernandes, MH; Noronha, JP; Pereira, CM; Rebelo, TS; Sales, MG; Silva, F, 2014)
"Metabolomic profiling of prostate cancer (PCa) progression identified markedly elevated levels of sarcosine (N-methyl glycine) in metastatic PCa and modest but significant elevation of the metabolite in PCa urine."1.39The role of sarcosine metabolism in prostate cancer progression. ( Asangani, IA; Ateeq, B; Athanikar, JN; Chinnaiyan, AM; Khan, AP; Mehra, R; Michailidis, G; Palapattu, G; Rajendiran, TM; Siddiqui, J; Sreekumar, A; Wei, JT; Yocum, AK, 2013)
"Moreover, patients with low grade prostate cancer had higher median SPON2 levels (p=0."1.39Spondin-2, a secreted extracellular matrix protein, is a novel diagnostic biomarker for prostate cancer. ( Battaglia, M; Bettocchi, C; Di Clemente, D; Ditonno, P; Galleggiante, V; Lucarelli, G; Palazzo, S; Rutigliano, M; Selvaggi, FP; Trabucco, S; Vavallo, A, 2013)
"Sarcosine was quantified using high-throughput liquid chromatography-mass spectrometry."1.39Prospective evaluation of serum sarcosine and risk of prostate cancer in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. ( Albanes, D; Andriole, G; Berndt, SI; Chu, LW; Fox, SD; Hoover, RN; Hsing, AW; Huang, WY; Issaq, HJ; Koutros, S; Meyer, TE; Veenstra, TD; Yu, K, 2013)
"Sarcosine has been identified as a differential metabolite that is greatly increased during progression from normal tissue to prostate cancer and metastatic disease."1.39Serum sarcosine is a risk factor for progression and survival in patients with metastatic castration-resistant prostate cancer. ( Battaglia, M; Bettocchi, C; Ditonno, P; Fanelli, M; Galleggiante, V; Germinario, CA; Larocca, AM; Lucarelli, G; Maiorano, E; Rutigliano, M; Selvaggi, FP; Spilotros, M; Vavallo, A, 2013)
"Sarcosine oxidase was shown to eliminate only sarcosine in the presence of D,L-alanine, and was consequently used as the selective enzyme."1.39Partial enzymatic elimination and quantification of sarcosine from alanine using liquid chromatography-tandem mass spectrometry. ( Burton, C; Gamagedara, S; Ma, Y, 2013)
"• The prostate cancer cell lines PC-3, LNCaP and DU145 were cultured in media containing 4, 20 or 100 nm of folic acid and assayed for growth over 9 days by counting viable cells at 3-day intervals, or for invasion by passage through a Matrigel-coated transwell membrane."1.38Elevated physiological levels of folic acid can increase in vitro growth and invasiveness of prostate cancer cells. ( Bakkar, A; Bismar, TA; Brockton, NT; Liu, S; Petersen, LF; Weljie, AM; Wen, J, 2012)
"Sarcosine is reported to be a differential metabolite that is greatly increased during prostate cancer (PCa) progression."1.38Serum sarcosine increases the accuracy of prostate cancer detection in patients with total serum PSA less than 4.0 ng/ml. ( Battaglia, M; Bettocchi, C; Ditonno, P; Fanelli, M; Germinario, CA; Larocca, AM; Lucarelli, G; Rutigliano, M; Selvaggi, FP; Vavallo, A, 2012)
"Current prostate cancer (PCa) diagnosis based on prostate-specific antigen (PSA) has been gradually losing its credibility over the last decade due to contradictory results in published literature and clinical practice."1.38Monitoring potential prostate cancer biomarkers in urine by capillary electrophoresis-tandem mass spectrometry. ( Chen, DD; Hewavitharana, AK; Hui, Y; Soliman, LC, 2012)
"Diagnosis of prostate cancer by prostate specific antigen (PSA) is error-prone and cannot distinguish benign prostatic hyperplasia (BPH) from malignant disease, nor identify aggressive and indolent types."1.38Plasma sarcosine does not distinguish early and advanced stages of prostate cancer. ( Bohm, L; Bouic, PJ; Fernandez, P; Harvey, J; Serafin, AM; Van der Watt, G, 2012)
"Sarcosine in prostate cancer tissue samples was recently reported to be increased during prostate cancer progression to metastasis and suggested to be a key metabolite of cancer cell invasion and aggressiveness."1.37Sarcosine in prostate cancer tissue is not a differential metabolite for prostate cancer aggressiveness and biochemical progression. ( Bethan, B; Jentzmik, F; Jung, K; Kamlage, B; Kristiansen, G; Lein, M; Miller, K; Stephan, C, 2011)
"Sarcosine is an amino acid derivative of N-methylglycine and is involved in the amino acid metabolism and methylation processes that are enriched during prostate cancer progression."1.37Sarcosine as a marker in prostate cancer progression: a rapid and simple method for its quantification in human urine by solid-phase microextraction-gas chromatography-triple quadrupole mass spectrometry. ( Cavaliere, B; Macchione, B; Monteleone, M; Naccarato, A; Sindona, G; Tagarelli, A, 2011)
"Thus, sarcosine may induce prostate cancer progression by increased HER2/neu expression."1.37Sarcosine induces increase in HER2/neu expression in androgen-dependent prostate cancer cells. ( Bouchelouche, K; Bouchelouche, P; Capala, J; Dahl, M; Kramer-Marek, G; Nordling, J, 2011)
"Sarcosine was suggested in a letter to Nature in 2009 as a biomarker for prostate cancer."1.37Is sarcosine a biomarker for prostate cancer? ( Issaq, HJ; Veenstra, TD, 2011)
"Sarcosine in urine was recently suggested to be a promising tool in prostate cancer (PCa) diagnostics."1.36Sarcosine in urine after digital rectal examination fails as a marker in prostate cancer detection and identification of aggressive tumours. ( Erbersdobler, A; Jentzmik, F; Jung, K; Kristiansen, G; Lein, M; Miller, K; Schrader, M; Stephan, C, 2010)
"Among the metabolites in PCa bone metastases especially cholesterol was noted."1.36Metabolomic characterization of human prostate cancer bone metastases reveals increased levels of cholesterol. ( Antti, H; Bergh, A; Crnalic, S; Hörnberg, E; Johansson, AI; Moritz, T; Stattin, P; Surowiec, I; Thysell, E; Widmark, A; Wikström, P, 2010)
"Sarcosine levels were also increased in invasive prostate cancer cell lines relative to benign prostate epithelial cells."1.35Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. ( Ahsan, A; Alexander, DC; Beecher, C; Berger, A; Byun, J; Cao, Q; Cao, X; Chinnaiyan, AM; Ghosh, D; Han, B; Kalyana-Sundaram, S; Khan, AP; Laxman, B; Li, Y; Lonigro, RJ; Mehra, R; Nyati, MK; Omenn, GS; Pennathur, S; Poisson, LM; Rajendiran, TM; Shuster, JR; Sreekumar, A; Varambally, S; Wei, JT; Yu, J, 2009)

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (8.22)29.6817
2010's60 (82.19)24.3611
2020's7 (9.59)2.80

Authors

AuthorsStudies
Ünlüer, ÖB1
Altunkök, N1
Özkütük, EB1
Ersöz, A1
Lin, X1
Tian, M1
Cao, C1
Shu, T1
Wen, Y1
Su, L1
Zhang, X2
Schcolnik-Cabrera, A1
Juárez-López, D1
Delkov, D1
Yoanıdu, L1
Tomov, D1
Stoyanova, R1
Dechev, I1
Uzunova, Y1
Yamani, HZ1
Safwat, N1
Mahmoud, AM1
Ayad, MF1
Abdel-Ghany, MF1
Gomaa, MM1
Farokhi, S1
Roushani, M1
Saedi, Z1
Markin, PA1
Brito, A1
Moskaleva, N1
Fodor, M1
Lartsova, EV1
Shpot, YV1
Lerner, YV1
Mikhajlov, VY1
Potoldykova, NV1
Enikeev, DV1
Lyundup, AV1
Appolonova, SA1
Rodrigo, MAM1
Strmiska, V4
Horackova, E1
Buchtelova, H1
Michalek, P3
Stiborova, M6
Eckschlager, T8
Adam, V12
Heger, Z11
Wang, YZ1
Ji, SY1
Xu, HY1
Zhao, W1
Xu, JJ1
Chen, HY1
Pacik, D4
Plevova, M3
Urbanova, L1
Lackova, Z3
Necas, A1
Narwal, V2
Kumar, P3
Joon, P1
Pundir, CS3
Wang, M1
Zou, L1
Liang, J1
Wang, X1
Zhang, D1
Fang, Y1
Zhang, J2
Xiao, F1
Liu, M1
Gumulec, J6
Raudenska, M2
Sorokac-Kubolkova, A1
Cernei, N7
Zitka, O7
Jaiwal, R1
Guran, R2
Krizkova, S2
Vanickova, L1
Klejdus, B1
Tvrdikova, E1
Keil, C1
Haase, H1
Liu, T2
Fu, B1
Chen, J4
Li, K1
Deswal, R1
Skalickova, S1
Sztalmachova, M1
Rodrigo, MA1
Sochor, J1
Masarik, M8
Hubalek, J1
Trnkova, L1
Kruseova, J1
Kizek, R6
Khan, AP3
Rajendiran, TM3
Ateeq, B1
Asangani, IA1
Athanikar, JN1
Yocum, AK1
Mehra, R3
Siddiqui, J1
Palapattu, G1
Wei, JT3
Michailidis, G1
Sreekumar, A3
Chinnaiyan, AM3
Lucarelli, G5
Rutigliano, M3
Bettocchi, C3
Palazzo, S1
Vavallo, A3
Galleggiante, V2
Trabucco, S1
Di Clemente, D1
Selvaggi, FP3
Battaglia, M3
Ditonno, P4
Koutros, S1
Meyer, TE1
Fox, SD1
Issaq, HJ2
Veenstra, TD2
Huang, WY1
Yu, K1
Albanes, D1
Chu, LW1
Andriole, G1
Hoover, RN1
Hsing, AW1
Berndt, SI1
Spilotros, M1
Fanelli, M2
Larocca, AM2
Germinario, CA2
Maiorano, E1
de Vogel, S1
Ulvik, A1
Meyer, K1
Ueland, PM1
Nygård, O1
Vollset, SE1
Tell, GS1
Gregory, JF1
Tretli, S1
Bjørge, T1
McDunn, JE1
Li, Z2
Adam, KP1
Neri, BP1
Wolfert, RL1
Milburn, MV1
Lotan, Y1
Wheeler, TM1
Green, T1
Chen, X1
Ryan, S1
Asch, AS1
Ruiz-Echevarría, MJ1
Babula, P1
Zhang, W1
Chen, Z1
Hrabec, R1
Lan, J1
Xu, W1
Wan, Q1
Lin, J1
Rebelo, TS1
Pereira, CM1
Sales, MG1
Noronha, JP1
Costa-Rodrigues, J1
Silva, F1
Fernandes, MH1
Kovács, GL1
Moein, MM1
Abdel-Rehim, A1
Abdel-Rehim, M1
Ferro, M2
Bruzzese, D1
Perdonà, S2
Mazzarella, C1
Perruolo, G1
Marino, A1
Cosimato, V2
Giorgio, E1
Tagliamonte, V1
Bottero, D2
De Cobelli, O2
Terracciano, D2
Kopel, P2
Hodek, P1
Valenti, G1
Rampazzo, E1
Biavardi, E1
Villani, E1
Fracasso, G1
Marcaccio, M1
Bertani, F1
Ramarli, D1
Dalcanale, E1
Paolucci, F1
Prodi, L1
Ankerst, DP1
Liss, M1
Zapata, D1
Hoefler, J1
Thompson, IM1
Leach, RJ1
Buonerba, C1
Deliu, VM1
Autorino, R1
Coman, I1
De Placido, S1
Di Lorenzo, G1
Polanska, H3
Ondrak, A1
Skoda, J1
Zitka, Z1
Kumar, D1
Gupta, A1
Mandhani, A1
Sankhwar, SN1
Merlos Rodrigo, MA2
Kulich, P1
Vit, V1
Abate-Shen, C1
Shen, MM1
Poisson, LM2
Cao, Q2
Yu, J2
Laxman, B2
Lonigro, RJ2
Li, Y2
Nyati, MK2
Ahsan, A2
Kalyana-Sundaram, S2
Han, B2
Cao, X2
Byun, J2
Omenn, GS2
Ghosh, D1
Pennathur, S2
Alexander, DC2
Berger, A2
Shuster, JR2
Varambally, S2
Beecher, C2
Couzin, J1
Kuehn, BM1
Darbon, JM1
Jamaspishvili, T1
Kral, M1
Khomeriki, I1
Student, V1
Kolar, Z1
Bouchal, J1
Williams, RM1
Naz, RK1
Cao, DL2
Yao, XD2
Jentzmik, F2
Stephan, C2
Miller, K2
Schrader, M1
Erbersdobler, A1
Kristiansen, G2
Lein, M2
Jung, K2
Baum, CE1
Price, DK1
Figg, WD1
Schalken, JA1
Struys, EA1
Heijboer, AC1
van Moorselaar, J1
Jakobs, C1
Blankenstein, MA1
Ghoshd, D1
Hewavitharana, AK2
Colleselli, D1
Stenzl, A1
Schwentner, C1
Thysell, E1
Surowiec, I1
Hörnberg, E1
Crnalic, S1
Widmark, A1
Johansson, AI1
Stattin, P1
Bergh, A1
Moritz, T1
Antti, H1
Wikström, P1
Wagner, C1
Luka, Z1
Kamlage, B1
Bethan, B1
Huang, CW1
Cai, H1
Shahinian, T1
Conti, PS1
Ye, DW1
Zhu, Y1
Zhang, HL1
Wang, YX1
Cavaliere, B1
Macchione, B1
Monteleone, M1
Naccarato, A1
Sindona, G1
Tagarelli, A1
Wu, H1
Ma, C1
Xue, R1
Deng, C1
Zeng, H1
Shen, X1
Dahl, M1
Bouchelouche, P1
Kramer-Marek, G1
Capala, J1
Nordling, J1
Bouchelouche, K1
Petersen, LF1
Brockton, NT1
Bakkar, A1
Liu, S1
Wen, J1
Weljie, AM1
Bismar, TA1
Moazzami, AA1
Zhang, JX1
Kamal-Eldin, A1
Aman, P1
Hallmans, G1
Johansson, JE1
Andersson, SO1
Soliman, LC1
Hui, Y1
Chen, DD1
Bohm, L1
Serafin, AM1
Fernandez, P1
Van der Watt, G1
Bouic, PJ1
Harvey, J1
Burton, C1
Gamagedara, S1
Ma, Y1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Uncovering the 'ORIGINS' of Diabetes[NCT02226640]80 participants (Actual)Observational2010-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for sarcosine and Cancer of Prostate

ArticleYear
Dual contribution of the mTOR pathway and of the metabolism of amino acids in prostate cancer.
    Cellular oncology (Dordrecht), 2022, Volume: 45, Issue:5

    Topics: Amino Acids; Arginine; Carbohydrates; Glutamine; Humans; Leucine; Lipids; Male; Proline; Prostatic N

2022
Quantitative analysis of sarcosine with special emphasis on biosensors: a review.
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2019, Volume: 24, Issue:5

    Topics: Alzheimer Disease; Amino Acid Metabolism, Inborn Errors; Biomarkers; Biosensing Techniques; Colorect

2019
Sarcosine as a potential prostate cancer biomarker--a review.
    International journal of molecular sciences, 2013, Jul-04, Volume: 14, Issue:7

    Topics: Biomarkers, Tumor; Chromatography, High Pressure Liquid; Databases, Factual; Glycine N-Methyltransfe

2013
[New challenges and earlier approved methods in the laboratory diagnosis of prostate cancer].
    Magyar onkologia, 2014, Volume: 58, Issue:4

    Topics: Antigens, Neoplasm; Biomarkers, Tumor; Biopsy; Digital Rectal Examination; Early Detection of Cancer

2014
Biomarkers in localized prostate cancer.
    Future oncology (London, England), 2016, Volume: 12, Issue:3

    Topics: DNA Methylation; Early Detection of Cancer; Humans; Male; MicroRNAs; Oncogene Proteins, Fusion; Pros

2016
Urine markers in monitoring for prostate cancer.
    Prostate cancer and prostatic diseases, 2010, Volume: 13, Issue:1

    Topics: Annexin A3; Antigens, Neoplasm; Biomarkers, Tumor; Comparative Genomic Hybridization; Gene Fusion; G

2010
Novel biomarkers and therapeutic targets for prostate cancer.
    Frontiers in bioscience (Scholar edition), 2010, 01-01, Volume: 2, Issue:2

    Topics: Anoctamins; Antigens, Neoplasm; Biomarkers, Tumor; Citric Acid; Endoplasmic Reticulum; Golgi Apparat

2010
Advances in biomarkers for the early diagnosis of prostate cancer.
    Chinese journal of cancer, 2010, Volume: 29, Issue:2

    Topics: Antigens, Neoplasm; Biomarkers, Tumor; Early Diagnosis; Endoribonucleases; Glutathione S-Transferase

2010

Trials

1 trial available for sarcosine and Cancer of Prostate

ArticleYear
Nuclear magnetic resonance-based metabolomics enable detection of the effects of a whole grain rye and rye bran diet on the metabolic profile of plasma in prostate cancer patients.
    The Journal of nutrition, 2011, Volume: 141, Issue:12

    Topics: 3-Hydroxybutyric Acid; Aged; Aged, 80 and over; Betaine; Cross-Over Studies; Diet; Homocysteine; Hum

2011

Other Studies

64 other studies available for sarcosine and Cancer of Prostate

ArticleYear
Graphenoxide Cross-Linker Based Potentiometric Biosensor Design for Sarcosine Determination.
    Protein and peptide letters, 2021, Volume: 28, Issue:11

    Topics: Biosensing Techniques; Graphite; Humans; Male; Prostatic Neoplasms; Sarcosine

2021
Using bimetallic Au/Cu nanoplatelets for construction of facile and label-free inner filter effect-based photoluminescence sensing platform for sarcosine detection.
    Analytica chimica acta, 2022, Feb-01, Volume: 1192

    Topics: Biomarkers, Tumor; Biosensing Techniques; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Male; P

2022
Oncometabolites in urine - a new opportunity for detection and prognosis of the clinical progress of verified prostate cancer-a pilot study.
    Turkish journal of medical sciences, 2022, Volume: 52, Issue:3

    Topics: Adult; Aged; beta-Alanine; Cross-Sectional Studies; Ethanolamines; Humans; Isoleucine; Kynurenine; M

2022
Point-of-care diagnostics for rapid determination of prostate cancer biomarker sarcosine: application of disposable potentiometric sensor based on oxide-conductive polymer nanocomposite.
    Analytical and bioanalytical chemistry, 2023, Volume: 415, Issue:22

    Topics: Biomarkers, Tumor; Humans; Male; Nanocomposites; Oxides; Point-of-Care Testing; Polymers; Prostate;

2023
Fabrication of an electrochemical aptasensor for the determination of sarcosine based on synthesized CuCo
    Analytical methods : advancing methods and applications, 2023, 09-28, Volume: 15, Issue:37

    Topics: Aptamers, Nucleotide; Biosensing Techniques; Electrochemical Techniques; Humans; Male; Prostatic Neo

2023
Plasma Sarcosine Measured by Gas Chromatography-Mass Spectrometry Distinguishes Prostatic Intraepithelial Neoplasia and Prostate Cancer from Benign Prostate Hyperplasia.
    Laboratory medicine, 2020, Nov-02, Volume: 51, Issue:6

    Topics: Aged; Aged, 80 and over; Biomarkers; Biomarkers, Tumor; Biopsy; Gas Chromatography-Mass Spectrometry

2020
Sarcosine influences apoptosis and growth of prostate cells via cell-type specific regulation of distinct sets of genes.
    The Prostate, 2018, Volume: 78, Issue:2

    Topics: Apoptosis; Biomarkers, Tumor; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasm Metasta

2018
Bidirectional Electrochemiluminescence Color Switch: An Application in Detecting Multimarkers of Prostate Cancer.
    Analytical chemistry, 2018, 03-06, Volume: 90, Issue:5

    Topics: 2,2'-Dipyridyl; Animals; Aptamers, Nucleotide; Biomarkers, Tumor; Biosensing Techniques; Colorimetry

2018
Identification of Sarcosine as a Target Molecule for the Canine Olfactory Detection of Prostate Carcinoma.
    Scientific reports, 2018, 03-21, Volume: 8, Issue:1

    Topics: Animals; Dogs; Feasibility Studies; Humans; Male; Prostatic Neoplasms; Sarcosine; Sensitivity and Sp

2018
Fabrication of an amperometric sarcosine biosensor based on sarcosine oxidase/chitosan/CuNPs/c-MWCNT/Au electrode for detection of prostate cancer.
    Enzyme and microbial technology, 2018, Volume: 113

    Topics: Biosensing Techniques; Chitosan; Copper; Dielectric Spectroscopy; Electrodes; Female; Gold; Humans;

2018
The Urinary Sarcosine/Creatinine Ratio is a Potential Diagnostic and Prognostic Marker in Prostate Cancer.
    Medical science monitor : international medical journal of experimental and clinical research, 2018, May-09, Volume: 24

    Topics: Area Under Curve; Biomarkers, Tumor; Creatinine; Humans; Male; Middle Aged; Neoplasm Grading; Neopla

2018
Post-treatment urinary sarcosine as a predictor of recurrent relapses in patients with prostate cancer.
    Cancer medicine, 2018, Volume: 7, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Biomarkers; Humans; Male; Neoplasm Recurrence, Local; Posto

2018
Construction and application of amperometric sarcosine biosensor based on SOxNPs/AuE for determination of prostate cancer.
    Biosensors & bioelectronics, 2018, Dec-30, Volume: 122

    Topics: Bacillus; Biosensing Techniques; Electrodes; Enzymes, Immobilized; Gold; Humans; Limit of Detection;

2018
Sarcosine is a prostate epigenetic modifier that elicits aberrant methylation patterns through the SAMe-Dnmts axis.
    Molecular oncology, 2019, Volume: 13, Issue:5

    Topics: Cell Line; CpG Islands; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Male; P

2019
An electrochemical sarcosine sensor based on biomimetic recognition.
    Mikrochimica acta, 2019, 02-01, Volume: 186, Issue:3

    Topics: Biomarkers, Tumor; Biomimetic Materials; Biosensing Techniques; Chitosan; Electrochemical Techniques

2019
Effect of sarcosine on antioxidant parameters and metallothionein content in the PC-3 prostate cancer cell line.
    Oncology reports, 2013, Volume: 29, Issue:6

    Topics: Biomarkers, Tumor; Cell Line, Tumor; Cell Survival; Free Radical Scavengers; Humans; Male; Metalloth

2013
The role of sarcosine metabolism in prostate cancer progression.
    Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:5

    Topics: Aged; Animals; Biomarkers, Tumor; Case-Control Studies; Cell Line, Tumor; Disease Progression; Gene

2013
Spondin-2, a secreted extracellular matrix protein, is a novel diagnostic biomarker for prostate cancer.
    The Journal of urology, 2013, Volume: 190, Issue:6

    Topics: Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Extracellular Matrix Proteins; Humans; Ma

2013
Prospective evaluation of serum sarcosine and risk of prostate cancer in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial.
    Carcinogenesis, 2013, Volume: 34, Issue:10

    Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Case-Control Studies; Early Detection of Cancer; Humans;

2013
Serum sarcosine is a risk factor for progression and survival in patients with metastatic castration-resistant prostate cancer.
    Future oncology (London, England), 2013, Volume: 9, Issue:6

    Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Castration; Disease-Free Survival; Docetaxel; Humans

2013
Sarcosine and other metabolites along the choline oxidation pathway in relation to prostate cancer--a large nested case-control study within the JANUS cohort in Norway.
    International journal of cancer, 2014, Jan-01, Volume: 134, Issue:1

    Topics: Betaine; Biomarkers, Tumor; Case-Control Studies; Choline; Chromatography, Liquid; Cohort Studies; G

2014
Metabolomic signatures of aggressive prostate cancer.
    The Prostate, 2013, Volume: 73, Issue:14

    Topics: Biomarkers, Tumor; Gas Chromatography-Mass Spectrometry; Humans; Male; Metabolomics; Neoplasm Gradin

2013
TMEFF2 and SARDH cooperate to modulate one-carbon metabolism and invasion of prostate cancer cells.
    The Prostate, 2013, Volume: 73, Issue:14

    Topics: Antimetabolites, Antineoplastic; Carbon; Cell Proliferation; Cell Transformation, Neoplastic; Gene K

2013
Sensitive determination of the potential biomarker sarcosine for prostate cancer by LC-MS with N,N'-dicyclohexylcarbodiimide derivatization.
    Journal of separation science, 2014, Volume: 37, Issue:1-2

    Topics: Biomarkers; Chromatography, High Pressure Liquid; Dicyclohexylcarbodiimide; Humans; Isomerism; Male;

2014
Determination of common urine substances as an assay for improving prostate carcinoma diagnostics.
    Oncology reports, 2014, Volume: 31, Issue:4

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Biomarkers, Tumor; Chromatography, Liquid; Disease Progress

2014
Colorimetric determination of sarcosine in urine samples of prostatic carcinoma by mimic enzyme palladium nanoparticles.
    Analytica chimica acta, 2014, May-12, Volume: 825

    Topics: Biomimetic Materials; Calibration; Colorimetry; Horseradish Peroxidase; Humans; Male; Metal Nanopart

2014
Sarcosine oxidase composite screen-printed electrode for sarcosine determination in biological samples.
    Analytica chimica acta, 2014, Nov-19, Volume: 850

    Topics: Biosensing Techniques; Electrodes; Enzymes, Immobilized; Humans; Hydrogen Peroxide; Limit of Detecti

2014
On-line determination of sarcosine in biological fluids utilizing dummy molecularly imprinted polymers in microextraction by packed sorbent.
    Journal of separation science, 2015, Volume: 38, Issue:5

    Topics: Adsorption; Automation; Biomarkers; Chromatography, High Pressure Liquid; Humans; Male; Molecular Im

2015
Improving the prediction of pathologic outcomes in patients undergoing radical prostatectomy: the value of prostate cancer antigen 3 (PCA3), prostate health index (phi) and sarcosine.
    Anticancer research, 2015, Volume: 35, Issue:2

    Topics: Antigens, Neoplasm; Humans; Male; Prostatectomy; Prostatic Neoplasms; ROC Curve; Sarcosine

2015
Paramagnetic nanoparticles as a platform for FRET-based sarcosine picomolar detection.
    Scientific reports, 2015, Mar-09, Volume: 5

    Topics: Antibodies, Monoclonal; Biomarkers, Tumor; Cell Line, Tumor; Dextrans; Fluorescence Resonance Energy

2015
An electrochemiluminescence-supramolecular approach to sarcosine detection for early diagnosis of prostate cancer.
    Faraday discussions, 2015, Volume: 185

    Topics: Early Detection of Cancer; Electrochemical Techniques; Humans; Limit of Detection; Luminescence; Mal

2015
A case control study of sarcosine as an early prostate cancer detection biomarker.
    BMC urology, 2015, Oct-01, Volume: 15

    Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Early Detection of Cancer; Humans; Male; Middle Aged; Pr

2015
Relation of exposure to amino acids involved in sarcosine metabolic pathway on behavior of non-tumor and malignant prostatic cell lines.
    The Prostate, 2016, Volume: 76, Issue:7

    Topics: Amino Acids; Cell Line; Cell Line, Tumor; Cell Movement; Glycine N-Methyltransferase; Humans; Male;

2016
Influence of Long-Distance Bicycle Riding on Serum/Urinary Biomarkers of Prostate Cancer.
    International journal of molecular sciences, 2016, Mar-17, Volume: 17, Issue:3

    Topics: Bicycling; Biomarkers, Tumor; C-Reactive Protein; Humans; Lactic Acid; Male; Middle Aged; Prostate-S

2016
NMR spectroscopy of filtered serum of prostate cancer: A new frontier in metabolomics.
    The Prostate, 2016, Volume: 76, Issue:12

    Topics: Aged; Biomarkers, Tumor; Biopsy; Citric Acid; Diagnosis, Differential; Digital Rectal Examination; G

2016
Prostate tumor attenuation in the nu/nu murine model due to anti-sarcosine antibodies in folate-targeted liposomes.
    Scientific reports, 2016, 09-20, Volume: 6

    Topics: Animals; Antibodies, Monoclonal; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationshi

2016
Sarcosine Up-Regulates Expression of Genes Involved in Cell Cycle Progression of Metastatic Models of Prostate Cancer.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Animals; Cell Cycle; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Glyc

2016
Diagnostics: The prostate-cancer metabolome.
    Nature, 2009, Feb-12, Volume: 457, Issue:7231

    Topics: Biomarkers; Humans; Male; Metabolome; Prostatic Neoplasms; Sarcosine

2009
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.
    Nature, 2009, Feb-12, Volume: 457, Issue:7231

    Topics: Androgens; Cell Line; Cell Line, Tumor; Disease Progression; Gene Knockdown Techniques; Glycine N-Me

2009
Biomarkers. Metabolite in urine may point to high-risk prostate cancer.
    Science (New York, N.Y.), 2009, Feb-13, Volume: 323, Issue:5916

    Topics: Biomarkers, Tumor; Humans; Male; Prostatic Neoplasms; Risk Factors; Sarcosine

2009
Promising marker found for deadly prostate cancer.
    JAMA, 2009, Mar-11, Volume: 301, Issue:10

    Topics: Biomarkers, Tumor; Humans; Male; Prostatic Neoplasms; Sarcosine

2009
[Analysis of the metabolome suggests a major potential role of sarcosine in the progression of cancer of the prostate].
    Bulletin du cancer, 2009, Volume: 96, Issue:4

    Topics: Dimethylglycine Dehydrogenase; Disease Progression; Glycine N-Methyltransferase; Humans; Male; Metab

2009
Beyond PSA: will future biomarker tests be better?
    Mayo Clinic health letter (English ed.), 2009, Volume: 27, Issue:8

    Topics: Biomarkers; Humans; Male; Mass Screening; Prostate-Specific Antigen; Prostatic Neoplasms; Sarcosine

2009
Sarcosine in urine after digital rectal examination fails as a marker in prostate cancer detection and identification of aggressive tumours.
    European urology, 2010, Volume: 58, Issue:1

    Topics: Aged; Biomarkers, Tumor; Cohort Studies; Creatinine; Digital Rectal Examination; Female; Humans; Mal

2010
Sarcosine as a potential prostate cancer biomarker and therapeutic target.
    Cancer biology & therapy, 2010, Mar-01, Volume: 9, Issue:5

    Topics: Biomarkers, Tumor; Humans; Male; Prostatic Neoplasms; Sarcosine

2010
Is urinary sarcosine useful to identify patients with significant prostate cancer? The trials and tribulations of biomarker development.
    European urology, 2010, Volume: 58, Issue:1

    Topics: Biomarkers, Tumor; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Sarcosine

2010
Serum sarcosine is not a marker for prostate cancer.
    Annals of clinical biochemistry, 2010, Volume: 47, Issue:Pt 3

    Topics: Biomarkers, Tumor; Humans; Male; Prostatic Neoplasms; Sarcosine

2010
Re: Florian Jentzmik, Carsten Stephan, Kurt Miller, et al. Sarcosine in urine after digital rectal examination fails as a marker in prostate cancer detection and identification of aggressive tumours. Eur Urol 2010;58:12-8.
    European urology, 2010, Volume: 58, Issue:3

    Topics: Biomarkers; Digital Rectal Examination; Humans; Male; Prostatic Neoplasms; Sarcosine

2010
Re: Florian Jentzmik, Carsten Stephan, Kurt Miller, et al. Sarcosine in urine after digital rectal examination fails as a marker in prostate cancer detection and identification of aggressive tumours. Eur Urol 2010;58:12-8.
    European urology, 2010, Volume: 58, Issue:4

    Topics: Biomarkers; Digital Rectal Examination; Humans; Male; Prostatic Neoplasms; Sarcosine

2010
Re: Florian Jentzmik, Carsten Stephan, Kurt Miller, et al. Sarcosine in urine after digital rectal examination fails as a marker in prostate cancer detection and identification of aggressive tumours. Eur Urol 2010;58:12-8.
    European urology, 2010, Volume: 58, Issue:5

    Topics: Biomarkers, Tumor; Humans; Male; Prostatic Neoplasms; Sarcosine

2010
Metabolomic characterization of human prostate cancer bone metastases reveals increased levels of cholesterol.
    PloS one, 2010, Dec-03, Volume: 5, Issue:12

    Topics: Biopsy; Bone and Bones; Bone Neoplasms; Cholesterol; Computational Biology; Gas Chromatography-Mass

2010
Sarcosine, folate metabolism and prostate cancer--is there a link?
    The Journal of urology, 2011, Volume: 185, Issue:2

    Topics: Biomarkers, Tumor; Case-Control Studies; Folic Acid; Humans; Male; Neoplasm Invasiveness; Neoplasm S

2011
Sarcosine in prostate cancer tissue is not a differential metabolite for prostate cancer aggressiveness and biochemical progression.
    The Journal of urology, 2011, Volume: 185, Issue:2

    Topics: Aged; Analysis of Variance; Biomarkers, Tumor; Biopsy, Needle; Cohort Studies; Diagnosis, Differenti

2011
Biological stability evaluation of the α2β1 receptor imaging agents: diamsar and DOTA conjugated DGEA peptide.
    Bioconjugate chemistry, 2011, Feb-16, Volume: 22, Issue:2

    Topics: Animals; Cell Line, Tumor; Copper Radioisotopes; Heterocyclic Compounds; Heterocyclic Compounds, 1-R

2011
Efforts to resolve the contradictions in early diagnosis of prostate cancer: a comparison of different algorithms of sarcosine in urine.
    Prostate cancer and prostatic diseases, 2011, Volume: 14, Issue:2

    Topics: Aged; Aged, 80 and over; Algorithms; Antigens, Neoplasm; Biomarkers, Tumor; Case-Control Studies; Ea

2011
Sarcosine as a marker in prostate cancer progression: a rapid and simple method for its quantification in human urine by solid-phase microextraction-gas chromatography-triple quadrupole mass spectrometry.
    Analytical and bioanalytical chemistry, 2011, Volume: 400, Issue:9

    Topics: Adult; Gas Chromatography-Mass Spectrometry; Humans; Male; Prostatic Neoplasms; Sarcosine; Sensitivi

2011
GC/MS-based metabolomic approach to validate the role of urinary sarcosine and target biomarkers for human prostate cancer by microwave-assisted derivatization.
    Analytical and bioanalytical chemistry, 2011, Volume: 401, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Gas Chromatography-Mass Spectrometry; Humans; Mal

2011
Sarcosine induces increase in HER2/neu expression in androgen-dependent prostate cancer cells.
    Molecular biology reports, 2011, Volume: 38, Issue:7

    Topics: Androgens; Cell Line, Tumor; Cell Membrane; Cell Survival; Gene Expression Regulation, Neoplastic; H

2011
Elevated physiological levels of folic acid can increase in vitro growth and invasiveness of prostate cancer cells.
    BJU international, 2012, Volume: 109, Issue:5

    Topics: Cell Proliferation; Folic Acid; Humans; Male; Neoplasm Invasiveness; Prostatic Neoplasms; Sarcosine;

2012
Is sarcosine a biomarker for prostate cancer?
    Journal of separation science, 2011, Volume: 34, Issue:24

    Topics: Biomarkers, Tumor; Humans; Male; Prostatic Neoplasms; Sarcosine

2011
Serum sarcosine increases the accuracy of prostate cancer detection in patients with total serum PSA less than 4.0 ng/ml.
    The Prostate, 2012, Volume: 72, Issue:15

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Biopsy; Case-Control Studies; Dis

2012
Monitoring potential prostate cancer biomarkers in urine by capillary electrophoresis-tandem mass spectrometry.
    Journal of chromatography. A, 2012, Dec-07, Volume: 1267

    Topics: Adult; Biomarkers; Electrophoresis, Capillary; Humans; Isomerism; Male; Prostatic Neoplasms; Sarcosi

2012
Plasma sarcosine does not distinguish early and advanced stages of prostate cancer.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2012, Jun-28, Volume: 102, Issue:8

    Topics: Alanine; Biomarkers, Tumor; Gas Chromatography-Mass Spectrometry; Humans; Male; Neoplasm Staging; Pr

2012
Partial enzymatic elimination and quantification of sarcosine from alanine using liquid chromatography-tandem mass spectrometry.
    Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:10

    Topics: Alanine; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Humans; Male; Oxidatio

2013