sarcosine has been researched along with Alzheimer Disease in 15 studies
cocobetaine: N-alkyl-betaine; cause of shampoo dermatitis
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent evidence indicates that U1-70K and other U1 small nuclear ribonucleoproteins are Sarkosyl-insoluble and associate with Tau neurofibrillary tangles selectively in Alzheimer disease (AD)." | 3.80 | Aggregation properties of the small nuclear ribonucleoprotein U1-70K in Alzheimer disease. ( Bishof, I; Diner, I; Duong, DM; Gearing, M; Hales, CM; Lah, JJ; Laur, O; Levey, AI; Rabenold, L; Seyfried, NT; Thambisetty, M; Troncoso, J; Yi, H, 2014) |
| "The severity of tau pathology in Alzheimer's disease brain correlates closely with disease progression." | 1.40 | Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease. ( Bohrmann, B; Collin, L; Göpfert, U; Grüninger, F; Oroszlan-Szovik, K; Ozmen, L, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 10 (66.67) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Tanas, A | 1 |
| Tozlu, ÖÖ | 1 |
| Gezmiş, T | 1 |
| Hacimüftüoğlu, A | 1 |
| Abd El-Aty, AM | 1 |
| Ceylan, O | 1 |
| Mardinoğlu, A | 1 |
| Türkez, H | 1 |
| Pan, RY | 1 |
| Zhang, J | 1 |
| Wang, J | 1 |
| Wang, Y | 2 |
| Li, Z | 1 |
| Liao, Y | 2 |
| Zhang, C | 1 |
| Liu, Z | 1 |
| Song, L | 1 |
| Yu, J | 1 |
| Yuan, Z | 1 |
| Diner, I | 2 |
| Nguyen, T | 1 |
| Seyfried, NT | 2 |
| Thygesen, C | 1 |
| Metaxas, A | 1 |
| Larsen, MR | 1 |
| Finsen, B | 1 |
| Nam, WH | 1 |
| Choi, YP | 1 |
| Pundir, CS | 1 |
| Deswal, R | 1 |
| Kumar, P | 1 |
| Ando, K | 1 |
| Kabova, A | 1 |
| Stygelbout, V | 1 |
| Leroy, K | 1 |
| Heraud, C | 1 |
| Frédérick, C | 1 |
| Suain, V | 1 |
| Yilmaz, Z | 1 |
| Authelet, M | 1 |
| Dedecker, R | 1 |
| Potier, MC | 1 |
| Duyckaerts, C | 1 |
| Brion, JP | 1 |
| Chu, J | 1 |
| Lauretti, E | 1 |
| Craige, CP | 1 |
| Praticò, D | 1 |
| Wang, G | 1 |
| Zhou, Y | 1 |
| Huang, FJ | 1 |
| Tang, HD | 1 |
| Xu, XH | 1 |
| Liu, JJ | 1 |
| Deng, YL | 1 |
| Ren, RJ | 1 |
| Xu, W | 1 |
| Ma, JF | 1 |
| Zhang, YN | 1 |
| Zhao, AH | 1 |
| Chen, SD | 1 |
| Jia, W | 1 |
| Collin, L | 1 |
| Bohrmann, B | 1 |
| Göpfert, U | 1 |
| Oroszlan-Szovik, K | 1 |
| Ozmen, L | 1 |
| Grüninger, F | 1 |
| Hales, CM | 1 |
| Bishof, I | 1 |
| Rabenold, L | 1 |
| Duong, DM | 1 |
| Yi, H | 1 |
| Laur, O | 1 |
| Gearing, M | 1 |
| Troncoso, J | 1 |
| Thambisetty, M | 1 |
| Lah, JJ | 1 |
| Levey, AI | 1 |
| Ke, YD | 1 |
| Delerue, F | 1 |
| Gladbach, A | 1 |
| Götz, J | 1 |
| Ittner, LM | 1 |
| Long, F | 1 |
| Cho, W | 1 |
| Ishii, Y | 1 |
| Sahara, N | 1 |
| Vega, IE | 1 |
| Ishizawa, T | 1 |
| Lewis, J | 1 |
| McGowan, E | 1 |
| Hutton, M | 1 |
| Dickson, D | 1 |
| Yen, SH | 1 |
| Hasegawa, M | 1 |
| Watanabe, A | 1 |
| Takio, K | 1 |
| Suzuki, M | 1 |
| Arai, T | 1 |
| Titani, K | 1 |
| Ihara, Y | 1 |
1 review available for sarcosine and Alzheimer Disease
| Article | Year |
|---|---|
Quantitative analysis of sarcosine with special emphasis on biosensors: a review.
Topics: Alzheimer Disease; Amino Acid Metabolism, Inborn Errors; Biomarkers; Biosensing Techniques; Colorect | 2019 |
14 other studies available for sarcosine and Alzheimer Disease
| Article | Year |
|---|---|
Topics: Aluminum; Aluminum Chloride; Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Antio | 2022 |
Intermittent fasting protects against Alzheimer's disease in mice by altering metabolism through remodeling of the gut microbiota.
Topics: Alzheimer Disease; Animals; Gastrointestinal Microbiome; Intermittent Fasting; Mice; Mice, Transgeni | 2022 |
Enrichment of Detergent-insoluble Protein Aggregates from Human Postmortem Brain.
Topics: Alzheimer Disease; Brain; Brain Chemistry; Detergents; Humans; Protein Aggregates; Proteomics; Prote | 2017 |
Age-Dependent Changes in the Sarkosyl-Insoluble Proteome of APPSWE/PS1ΔE9 Transgenic Mice Implicate Dysfunctional Mitochondria in the Pathogenesis of Alzheimer's Disease.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Disease Models, Animal; Ge | 2018 |
In vitro generation of tau aggregates conformationally distinct from parent tau seeds of Alzheimer's brain.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Green Fluorescent Proteins; HEK293 Cells; | 2019 |
Vaccination with Sarkosyl insoluble PHF-tau decrease neurofibrillary tangles formation in aged tau transgenic mouse model: a pilot study.
Topics: Aged, 80 and over; Alzheimer Disease; Animals; Brain; Disease Models, Animal; Female; Humans; Mice; | 2014 |
Pharmacological modulation of GSAP reduces amyloid-β levels and tau phosphorylation in a mouse model of Alzheimer's disease with plaques and tangles.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzamides; Cell | 2014 |
Plasma metabolite profiles of Alzheimer's disease and mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arachidonic Acid; Biomarkers; Chromatography, Liquid; Co | 2014 |
Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antibodies; Antibodies, Monoclonal; Blot | 2014 |
Aggregation properties of the small nuclear ribonucleoprotein U1-70K in Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Autopsy; Blotting, Western; Brain; Female; HEK293 Cells; | 2014 |
Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Blood Glucose; Comorbidity; Diabetes Mellitus, Experimental; Disease Mod | 2009 |
Expression and purification of 15N- and 13C-isotope labeled 40-residue human Alzheimer's β-amyloid peptide for NMR-based structural analysis.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Carbon Isotopes; Escherichia coli; Ge | 2011 |
Phosphorylated p38MAPK specific antibodies cross-react with sarkosyl-insoluble hyperphosphorylated tau proteins.
Topics: Age Factors; Alzheimer Disease; Animals; Antibodies; Antibody Specificity; Blotting, Western; Brain; | 2004 |
Characterization of two distinct monoclonal antibodies to paired helical filaments: further evidence for fetal-type phosphorylation of the tau in paired helical filaments.
Topics: Alzheimer Disease; Amino Acid Sequence; Animals; Animals, Newborn; Antibodies, Monoclonal; Brain; Ce | 1993 |