Page last updated: 2024-10-20

sarcosine and Acute Disease

sarcosine has been researched along with Acute Disease in 3 studies

cocobetaine: N-alkyl-betaine; cause of shampoo dermatitis

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"Agents that enhance N-methyl-D-aspartate (NMDA) function through the glycine modulatory site (D-serine, glycine, or D-cycloserine) or through glycine transporter 1 (sarcosine) improve the symptoms of patients with stable chronic schizophrenia."9.11Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study. ( Chang, YC; Chiu, CC; Lane, HY; Liu, YC; Tsai, GE, 2005)
"Mice with thermal and mechanical hypersensitivity after partial ligation of the sciatic nerve (Seltzer model) or mice with mechanical hypersensitivity after streptozotocin injection received intrathecal injection of glycine, sarcosine, and N-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine."7.74Glycine transporter inhibitors as a potential therapeutic strategy for chronic pain with memory impairment. ( Kodama, D; Ono, H; Takasu, K; Tanabe, M; Yamaguchi, S, 2008)
"Agents that enhance N-methyl-D-aspartate (NMDA) function through the glycine modulatory site (D-serine, glycine, or D-cycloserine) or through glycine transporter 1 (sarcosine) improve the symptoms of patients with stable chronic schizophrenia."5.11Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study. ( Chang, YC; Chiu, CC; Lane, HY; Liu, YC; Tsai, GE, 2005)
"Mice with thermal and mechanical hypersensitivity after partial ligation of the sciatic nerve (Seltzer model) or mice with mechanical hypersensitivity after streptozotocin injection received intrathecal injection of glycine, sarcosine, and N-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine."3.74Glycine transporter inhibitors as a potential therapeutic strategy for chronic pain with memory impairment. ( Kodama, D; Ono, H; Takasu, K; Tanabe, M; Yamaguchi, S, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Andrade, RB1
Gemelli, T1
Rojas, DB1
Dutra-Filho, CS1
Wannmacher, CM1
Lane, HY1
Chang, YC1
Liu, YC1
Chiu, CC1
Tsai, GE1
Tanabe, M1
Takasu, K1
Yamaguchi, S1
Kodama, D1
Ono, H1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
NMDA Enhancers in the Treatment of Schizophrenia[NCT00328276]Phase 220 participants Interventional2004-12-31Completed
NMDA Enhancers in the Treatment of Schizophrenia: Sarcosine vs. D-Serine[NCT00491569]Phase 260 participants (Actual)Interventional2005-01-31Completed
The Effects of Glycine Transport Inhibition on Brain Glycine Concentration[NCT00538070]68 participants (Actual)Interventional2007-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for sarcosine and Acute Disease

ArticleYear
Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study.
    Archives of general psychiatry, 2005, Volume: 62, Issue:11

    Topics: Acute Disease; Adult; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female;

2005
Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study.
    Archives of general psychiatry, 2005, Volume: 62, Issue:11

    Topics: Acute Disease; Adult; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female;

2005
Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study.
    Archives of general psychiatry, 2005, Volume: 62, Issue:11

    Topics: Acute Disease; Adult; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female;

2005
Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study.
    Archives of general psychiatry, 2005, Volume: 62, Issue:11

    Topics: Acute Disease; Adult; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female;

2005
Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study.
    Archives of general psychiatry, 2005, Volume: 62, Issue:11

    Topics: Acute Disease; Adult; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female;

2005
Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study.
    Archives of general psychiatry, 2005, Volume: 62, Issue:11

    Topics: Acute Disease; Adult; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female;

2005
Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study.
    Archives of general psychiatry, 2005, Volume: 62, Issue:11

    Topics: Acute Disease; Adult; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female;

2005
Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study.
    Archives of general psychiatry, 2005, Volume: 62, Issue:11

    Topics: Acute Disease; Adult; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female;

2005
Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study.
    Archives of general psychiatry, 2005, Volume: 62, Issue:11

    Topics: Acute Disease; Adult; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female;

2005

Other Studies

2 other studies available for sarcosine and Acute Disease

ArticleYear
Chemically induced acute model of sarcosinemia in wistar rats.
    Metabolic brain disease, 2016, Volume: 31, Issue:2

    Topics: Acute Disease; Amino Acid Metabolism, Inborn Errors; Animals; Animals, Newborn; Brain; Disease Model

2016
Glycine transporter inhibitors as a potential therapeutic strategy for chronic pain with memory impairment.
    Anesthesiology, 2008, Volume: 108, Issue:5

    Topics: Acute Disease; Analgesics; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glycine;

2008