sarcophytol-a and Cataract

sarcophytol-a has been researched along with Cataract* in 1 studies

Other Studies

1 other study(ies) available for sarcophytol-a and Cataract

Article	Year
Lens opacification and H2O2 elevation induced by a tumor promoter. Lens and eye toxicity research, 1992, Volume: 9, Issue:1 Incubation of whole bovine lens with 10(-7) M 12-O-tetradecanoylphorbol-13-acetate (TPA) led to the lens opacity within 24 h. The hydrogen peroxide (H2O2) concentration in the whole lens was elevated 4 fold after treatment with either 10(-7) M TPA or 2.5 mM glucose/20 microM glucose oxidase. The lens opacification and H2O2 elevation were TPA dose-dependent. Preincubation of the lens with anti-tumor promoting agents EGCG (epigallocatechin gallate) or Sarp A (sarcophytol A) stopped the TPA-mediated opacification process and suppressed H2O2 elevation. Topics: Animals; Antineoplastic Agents; Cataract; Catechin; Cattle; Diterpenes; Glucose; Glucose Oxidase; Hydrogen Peroxide; Lens, Crystalline; Tetradecanoylphorbol Acetate	1992

Article

Year

Lens opacification and H2O2 elevation induced by a tumor promoter.

Lens and eye toxicity research, 1992, Volume: 9, Issue:1

Incubation of whole bovine lens with 10(-7) M 12-O-tetradecanoylphorbol-13-acetate (TPA) led to the lens opacity within 24 h. The hydrogen peroxide (H2O2) concentration in the whole lens was elevated 4 fold after treatment with either 10(-7) M TPA or 2.5 mM glucose/20 microM glucose oxidase. The lens opacification and H2O2 elevation were TPA dose-dependent. Preincubation of the lens with anti-tumor promoting agents EGCG (epigallocatechin gallate) or Sarp A (sarcophytol A) stopped the TPA-mediated opacification process and suppressed H2O2 elevation.

Topics: Animals; Antineoplastic Agents; Cataract; Catechin; Cattle; Diterpenes; Glucose; Glucose Oxidase; Hydrogen Peroxide; Lens, Crystalline; Tetradecanoylphorbol Acetate

1992