sapropterin has been researched along with Vitiligo in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Borzova, VA; Buglak, AA; Telegina, TA; Vechtomova, YL | 1 |
| Beazley, W; Chavan, B; Ichinose, H; Rokos, H; Schallreuter, KU; Wood, JM | 1 |
| Gibbons, NC; Hasse, S; Marles, LK; Rokos, H; Schallreuter, KU | 1 |
| Calvo, A; Charubala, R; Maitland, DJ; Martinez, A; Pey, AL; Pfleiderer, W; Schallreuter, KU; Teigen, K; Wood, JM | 1 |
| Gibbons, NC; Peters, EM; Rokos, H; Schallreuter, KU; Spencer, JD; Wood, JM | 1 |
| Gütlich, M; Hitzemann, K; Lemke, KR; Pittelkow, MR; Rödl, W; Schallreuter, KU; Swanson, NN; Wood, JM; Ziegler, I | 1 |
| Gütlich, M; Lemke, KR; Lindsey, NJ; Pittelkow, MR; Schallreuter, KU; Wood, JM; Ziegler, I | 1 |
| Herrmann, FH; Hibberts, NA; Metelmann, HR; Moore, J; Panske, A; Sawatzki, J; Schallreuter, KU; Zschiesche, M | 1 |
| Blau, N; Schallreuter, KU | 1 |
| Schallreuter, KU | 1 |
| Beazley, WD; Behrens-Williams, SC; Blau, N; Dummer, R; Marles, LK; Moore, J; Peters, EM; Schallreuter, KU; Thöny, B; Wood, JM | 1 |
| Beazley, WD; Rokos, H; Schallreuter, KU | 1 |
1 review(s) available for sapropterin and Vitiligo
| Article | Year |
|---|---|
A review of recent advances on the regulation of pigmentation in the human epidermis.
Topics: Albinism, Oculocutaneous; alpha-MSH; Biopterins; Dihydroxyphenylalanine; Enzyme Activation; Epidermis; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Intramolecular Oxidoreductases; Keratinocytes; Melanocytes; Melanosomes; Membrane Glycoproteins; Membrane Proteins; Monophenol Monooxygenase; Oxidative Stress; Oxidoreductases; Phenylalanine; Phenylalanine Hydroxylase; Pro-Opiomelanocortin; Proteins; Racial Groups; Recombinant Fusion Proteins; Skin Pigmentation; Transfection; Tyrosine; Tyrosine 3-Monooxygenase; Vitiligo | 1999 |
1 trial(s) available for sapropterin and Vitiligo
| Article | Year |
|---|---|
Oxidative stress in vitiligo: photo-oxidation of pterins produces H(2)O(2) and pterin-6-carboxylic acid.
Topics: Biopterins; Catalase; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Epidermis; Humans; Hydrogen Peroxide; Oxidation-Reduction; Oxidative Stress; Oxygen; Photochemistry; Pteridines; Pterins; Ultraviolet Rays; Vitiligo | 2002 |
10 other study(ies) available for sapropterin and Vitiligo
| Article | Year |
|---|---|
Tetrahydrobiopterin as a Trigger for Vitiligo: Phototransformation during UV Irradiation.
Topics: Humans; Hypopigmentation; Polymers; Serum Albumin, Human; Ultraviolet Rays; Ultraviolet Therapy; Vitiligo | 2023 |
H(2)O(2) increases de novo synthesis of (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin via GTP cyclohydrolase I and its feedback regulatory protein in vitiligo.
Topics: Biopsy; Biopterins; Case-Control Studies; Catalase; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Epidermis; Feedback, Physiological; GTP Cyclohydrolase; Humans; Hydrogen Peroxide; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Oxidation-Reduction; Vitiligo | 2009 |
Perturbed 6-tetrahydrobiopterin recycling via decreased dihydropteridine reductase in vitiligo: more evidence for H2O2 stress.
Topics: Adolescent; Adult; Aged; Binding Sites; Biopterins; Computer Simulation; Dihydropteridine Reductase; Female; Gene Expression Regulation, Enzymologic; Humans; Hydrogen Peroxide; Male; Methionine; Middle Aged; Models, Biological; Oxidants; Oxidation-Reduction; Oxidative Stress; Protein Structure, Tertiary; RNA, Messenger; Vitiligo | 2004 |
Specific interaction of the diastereomers 7(R)- and 7(S)-tetrahydrobiopterin with phenylalanine hydroxylase: implications for understanding primapterinuria and vitiligo.
Topics: Binding Sites; Binding, Competitive; Biopterins; Computer Simulation; Humans; Kinetics; Magnetic Resonance Spectroscopy; Phenylalanine Hydroxylase; Protein Binding; Pterins; Spectrometry, Fluorescence; Stereoisomerism; Tyrosine 3-Monooxygenase; Vitiligo | 2006 |
Oxidative stress via hydrogen peroxide affects proopiomelanocortin peptides directly in the epidermis of patients with vitiligo.
Topics: Adrenocorticotropic Hormone; alpha-MSH; beta-Endorphin; Biopterins; Catalase; Cells, Cultured; Computer Simulation; Epidermis; Fourier Analysis; Humans; Hydrogen Peroxide; Melanins; Models, Biological; Oxidation-Reduction; Oxidative Stress; Peptide Fragments; Pro-Opiomelanocortin; Skin Pigmentation; Spectrum Analysis, Raman; Vitiligo | 2007 |
Regulation of melanin biosynthesis in the human epidermis by tetrahydrobiopterin.
Topics: Biopterins; Cell Differentiation; Cells, Cultured; Epidermis; GTP Cyclohydrolase; Humans; Keratinocytes; Melanins; Melanocytes; Phenylalanine Hydroxylase; Tyrosine; Vitiligo | 1994 |
Defective tetrahydrobiopterin and catecholamine biosynthesis in the depigmentation disorder vitiligo.
Topics: Base Sequence; Biopterins; Catecholamines; GTP Cyclohydrolase; Humans; Hydro-Lyases; Keratinocytes; Melanins; Melanocytes; Molecular Sequence Data; Monophenol Monooxygenase; Phenylalanine Hydroxylase; Phenylethanolamine N-Methyltransferase; Pterins; Skin; Vitiligo | 1994 |
In vivo evidence for compromised phenylalanine metabolism in vitiligo.
Topics: Adolescent; Adult; Biopterins; Cells, Cultured; Female; Gene Expression; GTP Cyclohydrolase; Humans; Hydro-Lyases; Kinetics; Male; Middle Aged; Phenylalanine; Phenylalanine Hydroxylase; RNA, Messenger; Skin; Spectrum Analysis, Raman; Tyrosine; Vitiligo | 1998 |
GTP-cyclohydrolase and vitiligo.
Topics: Antioxidants; Biopterins; Dystonia; GTP Cyclohydrolase; Humans; Mutation; Vitiligo | 1997 |
Epidermal H(2)O(2) accumulation alters tetrahydrobiopterin (6BH4) recycling in vitiligo: identification of a general mechanism in regulation of all 6BH4-dependent processes?
Topics: Biopterins; Catalase; Enzyme Activation; Epidermis; Humans; Hydro-Lyases; Hydrogen Peroxide; Isomerism; Mutation; Vitiligo | 2001 |