Page last updated: 2024-08-21

sapropterin and Shock, Septic

sapropterin has been researched along with Shock, Septic in 13 studies

Research

Studies (13)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (53.85)	18.2507
2000's	3 (23.08)	29.6817
2010's	3 (23.08)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Channon, KM; Crabtree, M; Heikal, L; Kelly, PD; Leiper, JM; Nandi, M; Sand, CA; Spina, D; Starr, A	1
De Backer, D; de Souza Barros, D; He, X; Lorent, S; Salgado, DR; Su, F; Taccone, FS; Velissaris, D; Vincent, JL	1
Dubin, A	1
Bahrami, S; Fitzal, F; Redl, H; Strohmaier, W; Werner, ER	1
Ren, J; Wu, S	1
Brand, MP; Bune, AJ; Cammack, R; Cook, HT; Heales, SJ; Shergill, JK	1
Boucher, JL; Denis-Henriot, D; Gaudiot, N; Giudicelli, Y; Jaubert, AM; Marcus, ML; Ribiere, C; Sabourault, D	1
Hattori, Y; Kasai, K; Murakami, Y; Nakanishi, N; Shimoda, S	1
Akimoto, K; Hattori, Y; Kasai, K; Nakanishi, N	1
Bhagat, K; Charles, IG; Hingorani, AD; Palacios, M; Vallance, P	1
Gross, SS; Hattori, Y; Kasai, K; Nakanishi, N	1
Galley, HF; Grant, IS; Le Cras, AE; Webster, NR; Yassen, K	1
Wachter, H; Weis, G; Werner, ER; Werner-Felmayer, G	1

Reviews

1 review(s) available for sapropterin and Shock, Septic

Article	Year
A burning issue: do sepsis and systemic inflammatory response syndrome (SIRS) directly contribute to cardiac dysfunction? Frontiers in bioscience : a journal and virtual library, 2006, Jan-01, Volume: 11 Topics: Animals; Biopterins; Cytokines; Diabetes Mellitus; Endothelin-1; Heart Diseases; Humans; Inflammation; Insulin Resistance; Myocardium; Nitric Oxide; Sepsis; Shock, Septic; Systemic Inflammatory Response Syndrome; Toll-Like Receptors	2006

Article

Year

A burning issue: do sepsis and systemic inflammatory response syndrome (SIRS) directly contribute to cardiac dysfunction?

Frontiers in bioscience : a journal and virtual library, 2006, Jan-01, Volume: 11

Topics: Animals; Biopterins; Cytokines; Diabetes Mellitus; Endothelin-1; Heart Diseases; Humans; Inflammation; Insulin Resistance; Myocardium; Nitric Oxide; Sepsis; Shock, Septic; Systemic Inflammatory Response Syndrome; Toll-Like Receptors

2006

Other Studies

12 other study(ies) available for sapropterin and Shock, Septic

Article	Year
Overexpression of GTP cyclohydrolase 1 feedback regulatory protein is protective in a murine model of septic shock. Shock (Augusta, Ga.), 2014, Volume: 42, Issue:5 Topics: Animals; Biopterins; Carrier Proteins; Disease Models, Animal; Gene Expression Regulation; Hemodynamics; Mice, Inbred C57BL; Mice, Transgenic; Nitric Oxide; Shock, Septic; Splanchnic Circulation	2014
Administration of tetrahydrobiopterin improves the microcirculation and outcome in an ovine model of septic shock. Critical care medicine, 2012, Volume: 40, Issue:10 Topics: Animals; Biopterins; Disease Models, Animal; Female; Hemodynamics; Microcirculation; Mouth Floor; Peritonitis; Pulmonary Gas Exchange; Random Allocation; Sheep; Shock, Septic	2012
Tetrahydrobiopterin (BH4) in septic shock: a key to solving the nitric oxide puzzle and opening the microcirculation? Critical care medicine, 2012, Volume: 40, Issue:10 Topics: Animals; Biopterins; Female; Microcirculation; Shock, Septic	2012
A 4-amino analogue of tetrahydrobiopterin attenuates endotoxin-induced hemodynamic alterations and organ injury in rats. Shock (Augusta, Ga.), 2002, Volume: 18, Issue:2 Topics: Animals; Biopterins; Blood Chemical Analysis; Blood Pressure Determination; Endotoxins; Escherichia coli; Heart Rate; Hemodynamics; Injections, Intraperitoneal; Male; Multiple Organ Failure; Nitric Oxide; Nitric Oxide Synthase; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity; Shock, Septic; Stroke Volume	2002
Inhibition of tetrahydrobiopterin synthesis reduces in vivo nitric oxide production in experimental endotoxic shock. Biochemical and biophysical research communications, 1996, Mar-07, Volume: 220, Issue:1 Topics: Animals; Biopterins; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; GTP Cyclohydrolase; Hypoxanthines; Immunohistochemistry; Kidney; Lipopolysaccharides; Male; Nitric Oxide; Rats; Rats, Inbred Lew; Shock, Septic	1996
White adipose tissue nitric oxide synthase: a potential source for NO production. Biochemical and biophysical research communications, 1996, May-24, Volume: 222, Issue:3 Topics: Adipose Tissue; Animals; Biopterins; Blotting, Western; Dexamethasone; Endotoxins; Enzyme Induction; Glucocorticoids; Isoenzymes; Lipopolysaccharides; Liver; Male; Myocardium; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Shock, Septic; Subcellular Fractions	1996
Tetrahydrobiopterin and GTP cyclohydrolase I in a rat model of endotoxic shock: relation to nitric oxide synthesis. Experimental physiology, 1996, Volume: 81, Issue:4 Topics: Anesthesia, General; Animals; Biopterins; Endotoxins; Enzyme Induction; GTP Cyclohydrolase; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Shock, Septic; Tissue Distribution; Up-Regulation	1996
Glucocorticoid regulation of nitric oxide and tetrahydrobiopterin in a rat model of endotoxic shock. Biochemical and biophysical research communications, 1997, Nov-17, Volume: 240, Issue:2 Topics: Adrenalectomy; Animals; Biopterins; Dexamethasone; Disease Models, Animal; Enzyme Induction; Escherichia coli; Glucocorticoids; GTP Cyclohydrolase; Hypotension; Kinetics; Lipopolysaccharides; Lung; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; RNA, Messenger; Shock, Septic; Transcription, Genetic	1997
Cytokine-induced venodilatation in humans in vivo: eNOS masquerading as iNOS. Cardiovascular research, 1999, Volume: 41, Issue:3 Topics: Adult; Arginine; Biopterins; Bradykinin; Endothelium, Vascular; Enzyme Inhibitors; Female; Gene Expression; Guanidines; Humans; Interleukin-1; Interleukin-6; Intracellular Signaling Peptides and Proteins; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norepinephrine; omega-N-Methylarginine; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Shock, Septic; Tumor Necrosis Factor-alpha; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents	1999
Adrenomedullin augments nitric oxide and tetrahydrobioptein synthesis in cytokine-stimulated vascular smooth muscle cells. Cardiovascular research, 1999, Volume: 44, Issue:1 Topics: Adrenomedullin; Analysis of Variance; Animals; Antioxidants; Biopterins; Cells, Cultured; Enzyme Activation; Gene Expression; GTP Cyclohydrolase; Interleukin-1; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Peptides; Polymerase Chain Reaction; Promoter Regions, Genetic; Rats; Rats, Wistar; RNA, Messenger; Shock, Septic; Vasodilator Agents	1999
Circulating tetrahydrobiopterin concentrations in patients with septic shock. British journal of anaesthesia, 2001, Volume: 86, Issue:4 Topics: APACHE; Biomarkers; Biopterins; Chromatography, High Pressure Liquid; Humans; Nitrates; Renal Insufficiency; Shock, Septic	2001
Tetrahydrobiopterin biosynthesis inhibition for diminishing nitric oxide production in cytokine-mediated septic shock. Journal of the National Cancer Institute, 1992, Nov-04, Volume: 84, Issue:21 Topics: Animals; Biopterins; Cytokines; Endothelium, Vascular; Humans; Mice; Nitric Oxide; Shock, Septic; Stimulation, Chemical; Swine	1992