Page last updated: 2024-08-21

sapropterin and Schizophrenia

sapropterin has been researched along with Schizophrenia in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (27.27)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (18.18)	29.6817
2010's	5 (45.45)	24.3611
2020's	1 (9.09)	2.80

Authors

Authors	Studies
Choo, T; Clelland, CL; Clelland, JD; Kantrowitz, JT; Lieberman, JA	1
Clelland, CL; Clelland, JD; Read, LL; Smeed, J	1
Clelland, CL; Clelland, JD; Cremers, S; Smeed, J	1
Okusaga, OO	1
Fukuda, K	1
Choi, YK; Tarazi, FI	1
Chao, HM; Clelland, JD; Guynn, RW; Read, LL; Reilly, MA; Richardson, MA; Suckow, RF; Taylor Clelland, CL	1
Clelland, CL; Clelland, JD; Read, LL; Reilly, MA; Richardson, MA	1
Aziz, AA; Blair, JA; Leeming, RJ	1
Davidson, JR; Duch, DS; Garbutt, JC; Nichol, CA; Woolf, JH	1
Ballenger, J; Bunney, WE; Garbutt, JC; Levine, RA; Lovenberg, WM; Murphy, DL; Sternberg, DE; van Kammen, DP	1

Reviews

1 review(s) available for sapropterin and Schizophrenia

Article	Year
Alterations in dopamine and glutamate neurotransmission in tetrahydrobiopterin deficient spr-/- mice: relevance to schizophrenia. BMB reports, 2010, Volume: 43, Issue:9 Topics: Alcohol Oxidoreductases; Animals; Biopterins; Dopamine; Glutamic Acid; Humans; Mice; Models, Biological; Schizophrenia; Synaptic Transmission	2010

Trials

1 trial(s) available for sapropterin and Schizophrenia

Article	Year
Adjunctive sapropterin dihydrochloride treatment in schizophrenia: A positive proof-of-concept, rater-blind, randomized, multivitamin-controlled study. Schizophrenia research, 2020, Volume: 218 Topics: Biopterins; Double-Blind Method; Humans; Phenylketonurias; Research Design; Schizophrenia	2020

Other Studies

9 other study(ies) available for sapropterin and Schizophrenia

Article	Year
Regulation of cortical and peripheral GCH1 expression and biopterin levels in schizophrenia-spectrum disorders. Psychiatry research, 2018, Volume: 262 Topics: Adult; Biopterins; Female; Frontal Lobe; GTP Cyclohydrolase; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Psychotic Disorders; Schizophrenia; Young Adult	2018
A tetrahydrobiopterin deficit finding in schizophrenia: A confirmation study. Schizophrenia research, 2019, Volume: 210 Topics: Adult; Biopterins; Comorbidity; Female; GTP Cyclohydrolase; Humans; Male; Phenylketonurias; Schizophrenia	2019
6R-l-erythro-5,6,7,8-tetrahydrobiopterin (BH4): a potential treatment for all symptom domains of schizophrenia. Medical hypotheses, 2014, Volume: 82, Issue:3 Topics: Biopterins; Humans; Models, Theoretical; Schizophrenia	2014
Integrated theory to unify status among schizophrenia and manic depressive illness. Medical hypotheses, 2015, Volume: 85, Issue:4 Topics: 5-Hydroxytryptophan; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Biopterins; Bipolar Disorder; Blood-Brain Barrier; Depression; Depression, Postpartum; Dopamine; Female; Hallucinations; Humans; Kynurenic Acid; Levodopa; Male; Neuroleptic Malignant Syndrome; Neurotransmitter Agents; Paranoid Disorders; Premenstrual Syndrome; Schizophrenia; Seasonal Affective Disorder; Serotonin; Serotonin Syndrome; Tyrosine	2015
Evidence for a tetrahydrobiopterin deficit in schizophrenia. Neuropsychobiology, 2005, Volume: 52, Issue:4 Topics: Adult; Biopterins; Demography; Female; Gene Expression Regulation, Enzymologic; Genetic Variation; Genotype; GTP Cyclohydrolase; Humans; Intracellular Signaling Peptides and Proteins; Male; Nitric Oxide; Phenylalanine; Proteins; Schizophrenia; Sequence Analysis, DNA	2005
Analysis of plasma biopterin levels in psychiatric disorders suggests a common BH4 deficit in schizophrenia and schizoaffective disorder. Neurochemical research, 2007, Volume: 32, Issue:1 Topics: Adult; Biopterins; Bipolar Disorder; Female; Humans; Male; Middle Aged; Psychotic Disorders; Schizophrenia	2007
Tetrahydrobiopterin metabolism in senile dementia of Alzheimer type. Journal of neurology, neurosurgery, and psychiatry, 1983, Volume: 46, Issue:5 Topics: Aged; Alzheimer Disease; Biopterins; Chlorpromazine; Female; Humans; Male; Neurotransmitter Agents; Schizophrenia	1983
Urinary excretion of biopterin and neopterin in psychiatric disorders. Psychiatry research, 1984, Volume: 11, Issue:2 Topics: Adult; Biopterins; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Middle Aged; Neopterin; Pteridines; Schizophrenia	1984
Cerebrospinal fluid hydroxylase cofactor in schizophrenia. Psychiatry research, 1982, Volume: 6, Issue:2 Topics: Adult; Biopterins; Blood Platelets; Female; Humans; Male; Monoamine Oxidase; Pteridines; Schizophrenia; Schizophrenic Psychology	1982