sapropterin has been researched along with Pain in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bjerrum, OJ; Dupont, E; Hellmund, V; Jensen, TS; Jespersgaard, C; Lykkesfeldt, J; Møller, AT; Møller, LB; Nachman, G; Nasser, A; Thorborg, SS | 1 |
| Bjerrum, OJ; Dalbøge, LS; Dupont, E; Heegaard, AM; Jensen, TS; Larsen, M; Møller, AT; Møller, LB; Nasser, A | 1 |
| Allen, D; Belfer, I; Channon, KM; Cunnington, C; Darbari, DS; Desai, K; Diaw, L; Dizon, M; Freeman, L; Goldman, D; Hartley, SW; Kato, GJ; Milton, J; Nolan, V; Steinberg, MH; Taylor, JG; Wang, Z; Youngblood, V | 1 |
| Ali, S; Bjerrum, OJ; Møller, LB; Nasser, A; Wilsbech, S | 1 |
| Gordh, T; Miclescu, A | 1 |
| Blagg, J; Hopkins, AL; Naylor, AM; Pojasek, KR | 1 |
| Abele, A; Adolph, J; Allchorne, A; Atlas, SJ; Belfer, I; Binshtok, AM; Carlezon, WA; Costigan, M; Diatchenko, L; Ehnert, C; Fillingim, RB; Geisslinger, G; Goldman, D; Griffin, RS; Lötsch, J; Maixner, W; Marian, C; Max, MB; Nejim, J; Parsegian, A; Sama, S; Schmidt, H; Scholz, J; Tegeder, I; Woolf, CJ; Wu, T | 1 |
| Inturrisi, CE; Pasternak, GW | 1 |
2 review(s) available for sapropterin and Pain
| Article | Year |
|---|---|
Nitric oxide and pain: 'Something old, something new'.
Topics: Animals; Biopterins; Cyclic AMP; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Humans; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nociceptors; omega-N-Methylarginine; Pain; Prostaglandin-Endoperoxide Synthases; Reactive Nitrogen Species; Reactive Oxygen Species; Signal Transduction | 2009 |
The tetrahydrobiopterin pathway and pain.
Topics: Alcohol Oxidoreductases; Animals; Biopterins; Drug Discovery; GTP Cyclohydrolase; Humans; Pain; Peripheral Nervous System Diseases; Signal Transduction | 2010 |
6 other study(ies) available for sapropterin and Pain
| Article | Year |
|---|---|
Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Animals; Biopterins; Capsaicin; Cells, Cultured; Cohort Studies; Cytokines; Dystonic Disorders; Female; Fibroblasts; Genotype; GTP Cyclohydrolase; Humans; Male; Middle Aged; Mutation; Neoptera; Pain; Pain Threshold; Sex Factors; Young Adult | 2018 |
Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain.
Topics: Animals; Behavior, Animal; Biopterins; Biosynthetic Pathways; Capsaicin; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Disease Models, Animal; Dystonic Disorders; Formaldehyde; Freund's Adjuvant; GTP Cyclohydrolase; Hot Temperature; Inflammation; Inheritance Patterns; Mice; Mice, Inbred C57BL; Motor Activity; Nociception; Pain; Phenylketonurias; Physical Stimulation; Rats; Stress, Mechanical | 2013 |
A GCH1 haplotype confers sex-specific susceptibility to pain crises and altered endothelial function in adults with sickle cell anemia.
Topics: Adult; Alleles; Anemia, Sickle Cell; Biopterins; Case-Control Studies; Endothelium; Female; Gene Expression Regulation; Gene Frequency; Genetic Association Studies; Genetic Markers; Genetic Predisposition to Disease; GTP Cyclohydrolase; Haplotypes; Humans; Male; Middle Aged; Odds Ratio; Pain; Pain Management; Phenotype; Plethysmography; Sex Factors; Transcriptome; Vascular Diseases; Young Adult | 2014 |
Intraplantar injection of tetrahydrobiopterin induces nociception in mice.
Topics: Animals; Biopterins; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Female; Hindlimb; Mice; Nitric Oxide; Nitric Oxide Synthase; Nociception; Pain; TRPV Cation Channels | 2015 |
GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence.
Topics: Adult; Alcohol Oxidoreductases; Animals; Biopterins; Enzyme Inhibitors; GTP Cyclohydrolase; Haplotypes; Humans; Pain; Pain Management; Pain Threshold; Prospective Studies; Rats | 2006 |
Feeling pain? Who's your daddy....
Topics: Animals; Biopterins; GTP Cyclohydrolase; Humans; Neuronal Plasticity; Pain; Rats; Receptors, Serotonin, 5-HT3 | 2006 |