Page last updated: 2024-08-21

sapropterin and Neurodegenerative Diseases

sapropterin has been researched along with Neurodegenerative Diseases in 4 studies

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (75.00)	29.6817
2010's	1 (25.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ha, SH; Han, J; Kim, HK	1
Choi, HJ; Hwang, O; Kim, SW; Lee, SY	1
Kotsonis, P; Matter, H	1
Choi, JJ; Choi, JW; Kim, HC; Kim, HS; Kim, WK; Ko, KH; Lee, JC; Lee, SJ; Ryu, JR; Shin, CY	1

Reviews

2 review(s) available for sapropterin and Neurodegenerative Diseases

Article	Year
Potential therapeutic applications of tetrahydrobiopterin: from inherited hyperphenylalaninemia to mitochondrial diseases. Annals of the New York Academy of Sciences, 2010, Volume: 1201 Topics: Animals; Antioxidants; Binding Sites; Biopterins; Humans; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Diseases; Models, Biological; Mutation; Neurodegenerative Diseases; Phenylketonurias; Reactive Oxygen Species	2010
Biology and chemistry of the inhibition of nitric oxide synthases by pteridine-derivatives as therapeutic agents. Medicinal research reviews, 2004, Volume: 24, Issue:5 Topics: Animals; Arginine; Binding Sites; Biopterins; Brain Ischemia; Enzyme Inhibitors; Humans; Inflammation; Isoenzymes; Neurodegenerative Diseases; Nitric Oxide Synthase; Protein Conformation; Pteridines; Quantitative Structure-Activity Relationship; Sepsis; Structure-Activity Relationship	2004

Article

Year

Potential therapeutic applications of tetrahydrobiopterin: from inherited hyperphenylalaninemia to mitochondrial diseases.

Annals of the New York Academy of Sciences, 2010, Volume: 1201

Topics: Animals; Antioxidants; Binding Sites; Biopterins; Humans; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Diseases; Models, Biological; Mutation; Neurodegenerative Diseases; Phenylketonurias; Reactive Oxygen Species

2010

Biology and chemistry of the inhibition of nitric oxide synthases by pteridine-derivatives as therapeutic agents.

Medicinal research reviews, 2004, Volume: 24, Issue:5

Topics: Animals; Arginine; Binding Sites; Biopterins; Brain Ischemia; Enzyme Inhibitors; Humans; Inflammation; Isoenzymes; Neurodegenerative Diseases; Nitric Oxide Synthase; Protein Conformation; Pteridines; Quantitative Structure-Activity Relationship; Sepsis; Structure-Activity Relationship

2004

Other Studies

2 other study(ies) available for sapropterin and Neurodegenerative Diseases

Article	Year
Dopamine-dependent cytotoxicity of tetrahydrobiopterin: a possible mechanism for selective neurodegeneration in Parkinson's disease. Journal of neurochemistry, 2003, Volume: 86, Issue:1 Topics: Animals; Antioxidants; Biopterins; Cell Death; Cell Line; Central Nervous System; Dopamine; Humans; Iron Chelating Agents; Lipid Peroxidation; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; NAD(P)H Dehydrogenase (Quinone); Neuroblastoma; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Proteins; Quinones; Toxicity Tests; Tyrosine 3-Monooxygenase	2003
Glucose deprivation decreases nitric oxide production via NADPH depletion in immunostimulated rat primary astrocytes. Glia, 2002, Mar-01, Volume: 37, Issue:3 Topics: Adjuvants, Immunologic; Animals; Animals, Newborn; Astrocytes; Biopterins; Cell Death; Cells, Cultured; Central Nervous System; Deoxyglucose; Down-Regulation; Glucose; Glutathione; Interferon-gamma; Lactic Acid; Lipopolysaccharides; NADP; Neurodegenerative Diseases; Nitric Oxide; Nitric Oxide Synthase; Pyruvic Acid; Rats; Rats, Sprague-Dawley	2002

Article

Year

Dopamine-dependent cytotoxicity of tetrahydrobiopterin: a possible mechanism for selective neurodegeneration in Parkinson's disease.

Journal of neurochemistry, 2003, Volume: 86, Issue:1

Topics: Animals; Antioxidants; Biopterins; Cell Death; Cell Line; Central Nervous System; Dopamine; Humans; Iron Chelating Agents; Lipid Peroxidation; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; NAD(P)H Dehydrogenase (Quinone); Neuroblastoma; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Proteins; Quinones; Toxicity Tests; Tyrosine 3-Monooxygenase

2003

Glucose deprivation decreases nitric oxide production via NADPH depletion in immunostimulated rat primary astrocytes.

Glia, 2002, Mar-01, Volume: 37, Issue:3

Topics: Adjuvants, Immunologic; Animals; Animals, Newborn; Astrocytes; Biopterins; Cell Death; Cells, Cultured; Central Nervous System; Deoxyglucose; Down-Regulation; Glucose; Glutathione; Interferon-gamma; Lactic Acid; Lipopolysaccharides; NADP; Neurodegenerative Diseases; Nitric Oxide; Nitric Oxide Synthase; Pyruvic Acid; Rats; Rats, Sprague-Dawley

2002