sapropterin has been researched along with Nervous System Disorders in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hill, R | 1 |
| Ichinose, H; Nomura, T; Sumi-Ichinose, C | 1 |
| Shintaku, H | 1 |
| Allen, GF; Clayton, PT; Footitt, EJ; Heales, SJ; Mills, PB; Oppenheim, M | 1 |
| Leeming, RJ | 1 |
| Candito, M; Chambon, P; Chatel, M; Nagatsu, T | 1 |
| Heales, SJ; Hyland, K | 1 |
| Hirayama, K; Kapatos, G; Lentz, SI; Stegenga, S; Zhu, M | 1 |
| Suzuki, T | 1 |
| Dhondt, JL; Netter, JC; Petrus, M; Rance, F | 1 |
| al Aqeel, A; al Nasser, M; Blau, N; Brismar, J; Gascon, G; Hughes, H; Nester, M; Ozand, PT; Reynolds, CT; Subramanyan, SB | 1 |
| Duch, DS; Nichol, CA; Smith, GK | 1 |
| Watts, RW | 1 |
| Blonder, J; Cohen, BE; Normand, M; Peled, I; Quint, J; Szeinberg, A | 1 |
6 review(s) available for sapropterin and Nervous System Disorders
| Article | Year |
|---|---|
[Biopterin and child neurologic disease].
Topics: Biopterins; Child; Dystonia; Humans; Nervous System Diseases; Phenylketonurias | 2009 |
The role of tetrahydrobiopterin in neurological disease: a review.
Topics: Aluminum; Biopterins; Brain; Dementia; Humans; Lead Poisoning; Nervous System Diseases; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Pteridines | 1981 |
Differential metabolism of tetrahydrobiopterin in monoamine neurons: a hypothesis based upon clinical and basic research.
Topics: Animals; Biogenic Monoamines; Biopterins; Brain; Depressive Disorder; Humans; Hypothalamus; Mesencephalon; Nervous System Diseases; Neurons | 1993 |
[Inborn errors of catecholamine metabolism].
Topics: Amino Acid Metabolism, Inborn Errors; Aromatic-L-Amino-Acid Decarboxylases; Biopterins; Catecholamines; Diagnosis, Differential; Dopamine beta-Hydroxylase; Humans; Monoamine Oxidase; Nervous System Diseases; Prognosis | 2000 |
Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin.
Topics: Alcohol Oxidoreductases; Animals; Biopterins; Body Fluids; Coenzymes; GTP Cyclohydrolase; Humans; Immune System Diseases; Mental Disorders; Metalloproteins; Molybdenum; Molybdenum Cofactors; Neoplasms; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines; Pterins; Tetrahydrofolate Dehydrogenase; Tissue Distribution; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 1985 |
Defects of tetrahydrobiopterin synthesis and their possible relationship to a disorder of purine metabolism (the Lesch-Nyhan syndrome).
Topics: Biopterins; Brain; Dopamine; GTP Cyclohydrolase; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Nervous System Diseases; Neurotransmitter Agents; Pteridines; Pterins; Purines | 1985 |
1 trial(s) available for sapropterin and Nervous System Disorders
| Article | Year |
|---|---|
Tetrahydrobiopterin and quinonoid dihydrobiopterin concentrations in CSF from patients with dihydropteridine reductase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Biopterins; Child; Child, Preschool; Humans; Infant; Nervous System Diseases; Oxidoreductases | 1993 |
7 other study(ies) available for sapropterin and Nervous System Disorders
| Article | Year |
|---|---|
Combating side effects of sulfonamides.
Topics: Anti-Bacterial Agents; Bacterial Infections; Biopterins; Dopamine; Humans; Nervous System Diseases; Nitric Oxide Synthase; Sulfonamides | 2013 |
Metabolism of tetrahydrobiopterin: its relevance in monoaminergic neurons and neurological disorders.
Topics: Animals; Biogenic Monoamines; Biopterins; Dystonic Disorders; GTP Cyclohydrolase; Mice; Mice, Knockout; Mixed Function Oxygenases; Nervous System Diseases; Neurons; Parkinson Disease | 2008 |
Pyridoxal 5'-phosphate in cerebrospinal fluid; factors affecting concentration.
Topics: Adolescent; Adult; Biopterins; Child; Child, Preschool; Cysteine; Epilepsy; False Positive Reactions; Female; Free Radicals; Humans; Infant; Infant, Newborn; Levodopa; Male; Metabolism, Inborn Errors; Middle Aged; Nervous System Diseases; Oxygen; Pyridoxal Phosphate; Reference Values; Reproducibility of Results; Sulfites; Tetrahydrofolates | 2011 |
High-performance liquid chromatographic measurement of cerebrospinal fluid tetrahydrobiopterin, neopterin, homovanillic acid and 5-hydroxindoleacetic acid in neurological diseases.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Aged, 80 and over; Biopterins; Chromatography, High Pressure Liquid; Dopamine; Drug Stability; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Neopterin; Nervous System Diseases; Reproducibility of Results; Serotonin | 1994 |
[Early neurotoxicity of high-dose of methotrexate and tetrahydrobiopterin deficiency].
Topics: Biopterins; Child; Humans; Male; Methotrexate; Nervous System Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1991 |
Biopterin-dependent hyperphenylalaninemia due to deficiency of 6-pyruvoyl tetrahydropterin synthase.
Topics: Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Biopterins; Female; Humans; Infant; Male; Nervous System Diseases; Phenylalanine; Phosphorus-Oxygen Lyases; Saudi Arabia | 1991 |
Malignant phenylketonuria due to defective synthesis of dihydrobiopterin.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Drug Combinations; Female; Humans; Infant, Newborn; Levodopa; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines; Tyrosine | 1985 |