sapropterin has been researched along with Machado-Joseph Disease in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Antoku, Y; Iwashita, H; Matsuishi, T; Sakai, T | 1 |
| Sakai, T | 3 |
2 trial(s) available for sapropterin and Machado-Joseph Disease
| Article | Year |
|---|---|
Tetrahydrobiopterin double-blind, crossover trial in Machado-Joseph disease.
Topics: Adult; Antioxidants; Biopterins; Cross-Over Studies; Double-Blind Method; Humans; Machado-Joseph Disease; Male; Middle Aged | 1996 |
[A possibility of therapeutic trial with tetrahydrobiopterin, which was suggested by the administration of sulfamethoxazole-trimethoprim].
Topics: Anti-Infective Agents; Biopterins; Double-Blind Method; Humans; Machado-Joseph Disease; Trimethoprim, Sulfamethoxazole Drug Combination | 1996 |
2 other study(ies) available for sapropterin and Machado-Joseph Disease
| Article | Year |
|---|---|
Trimethoprim-sulfamethoxazole and biopterin treatment in Machado-Joseph disease.
Topics: Antioxidants; Biopterins; Humans; Machado-Joseph Disease; Neurologic Examination; Trimethoprim, Sulfamethoxazole Drug Combination | 1998 |
Effects of tetrahydrobiopterin on ataxia in Machado-Joseph disease may be based upon the theory of 'cerebellar long-term depression'.
Topics: Biopterins; Brain; Cross-Over Studies; Cytoplasmic Granules; Double-Blind Method; Guanylate Cyclase; Humans; Machado-Joseph Disease; Nitric Oxide Synthase; Placebos; Purkinje Cells | 2001 |