Compounds > sapropterin
Page last updated: 2024-08-21

sapropterin and Left Ventricular Hypertrophy

sapropterin has been researched along with Left Ventricular Hypertrophy in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bai, F; Chang, P; Li, X; Lin, X; Wang, Q; Xu, H; Yang, M; Yu, J; Zhang, X; Zhang, Z; Zhao, F; Zhao, X1
Fujita, M; Iwasaka, T; Otani, H; Shimazu, T; Shiojima, I; Yoshioka, K1
Bedja, D; Carnicer, R; Casadei, B; Channon, KM; Duglan, D; Hahn, VS; Hashimoto, T; Kass, DA; Recalde, A; Sivakumaran, V; Zhu, G1
Arkenbout, EK; Barker, N; Barouch, LA; Bedja, D; Champion, HC; Channon, KM; Chen, J; Cingolani, O; Gabrielson, KL; Hale, AB; Halushka, MK; Kaminski, PM; Kass, DA; Leyton-Mange, JS; Moens, AL; Niu, X; Wolin, MS; Wuyts, FL; Xia, Y; Yang, R1
Alp, NJ; Channon, KM; Kass, DA; Ketner, EA; Moens, AL; O'Neill, CA; Schmidt, TS; Takimoto, E; Wolin, MS1
Dunster, C; Grieve, DJ; Kelly, FJ; Li, JM; MacCarthy, PA; Shah, AM1

Other Studies

6 other study(ies) available for sapropterin and Left Ventricular Hypertrophy

ArticleYear
Tetrahydrobiopterin reverse left ventricular hypertrophy and diastolic dysfunction through the PI3K/p-Akt pathway in spontaneously hypertensive rats.
    Biochemical and biophysical research communications, 2015, Aug-07, Volume: 463, Issue:4

    Topics: Animals; Biopterins; Blood Pressure; Body Weight; Diastole; Hypertension; Hypertrophy, Left Ventricular; Male; Organ Size; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Valine; Valsartan

2015
Sepiapterin prevents left ventricular hypertrophy and dilatory remodeling induced by pressure overload in rats.
    American journal of physiology. Heart and circulatory physiology, 2015, Nov-15, Volume: 309, Issue:10

    Topics: Animals; Aorta; Biopterins; Capillaries; Cell Size; Constriction; Dilatation, Pathologic; Enzyme Inhibitors; Glycine; Heart; Hypertrophy, Left Ventricular; Male; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Oxidative Stress; Pressure; Pterins; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Ultrasonography; Ventricular Dysfunction, Left; Ventricular Remodeling

2015
Tetrahydrobiopterin Protects Against Hypertrophic Heart Disease Independent of Myocardial Nitric Oxide Synthase Coupling.
    Journal of the American Heart Association, 2016, Mar-21, Volume: 5, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Biopterins; Cardiovascular Agents; Cytokines; Cytoprotection; Disease Models, Animal; GTP Cyclohydrolase; Humans; Hypertrophy, Left Ventricular; Inflammation Mediators; Macrophages; Mice, Transgenic; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Signal Transduction; Superoxides; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2016
Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the beta3-adrenoreceptor.
    Journal of molecular and cellular cardiology, 2009, Volume: 47, Issue:5

    Topics: Age Factors; Animals; Biopterins; Blotting, Western; Cardiomyopathies; Echocardiography; Hypertrophy, Left Ventricular; Male; Mice; Mice, Mutant Strains; Nitric Oxide Synthase; Oxidative Stress; Receptors, Adrenergic, beta-3; Superoxides; Vasoconstriction; Ventricular Remodeling

2009
Bi-modal dose-dependent cardiac response to tetrahydrobiopterin in pressure-overload induced hypertrophy and heart failure.
    Journal of molecular and cellular cardiology, 2011, Volume: 51, Issue:4

    Topics: Analysis of Variance; Animals; Biopterins; Cardiotonic Agents; Dose-Response Relationship, Drug; Heart Failure; Humans; Hypertrophy, Left Ventricular; Ligation; Mice; Mice, Inbred C57BL; Myocardium; Random Allocation; Superoxides; Ventricular Function, Left; Ventricular Remodeling

2011
Impaired endothelial regulation of ventricular relaxation in cardiac hypertrophy: role of reactive oxygen species and NADPH oxidase.
    Circulation, 2001, Dec-11, Volume: 104, Issue:24

    Topics: Animals; Antioxidants; Arginine; Ascorbic Acid; Biopterins; Deferoxamine; Drug Synergism; Endothelium, Vascular; Free Radical Scavengers; Glutathione; Guinea Pigs; Heart Ventricles; Hypertrophy, Left Ventricular; In Vitro Techniques; Male; Malondialdehyde; Metalloporphyrins; Myocardial Contraction; NADPH Oxidases; Oxidation-Reduction; Reactive Oxygen Species; Substance P

2001