Compounds > sapropterin
Page last updated: 2024-08-21

sapropterin and Ischemia

sapropterin has been researched along with Ischemia in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's8 (80.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Akaihata, H; Hata, J; Honda-Takinami, R; Kataoka, M; Kojima, Y; Matsuoka, K; Ogawa, S; Sato, Y; Tanji, R1
De Backer, D; Orbegozo, D; Rahmania, L; Su, F; Taccone, FS; Vincent, JL1
De Backer, D; Rahmania, L; Vincent, JL1
Kinoshita, H; Otake, K; Yamasaki, T1
Ambrosio, G; Boslett, J; De Pascali, F; Druhan, LJ; El-Mahdy, M; Hemann, C; Reyes, LA; Varadharaj, S; Zweier, JL1
Hoffman, A; Messina, LM; Nowicki, PT; Tie, G; Yan, J; Yang, Y1
Messina, LM; Tie, G; Yan, J2
Brandacher, G; Cardini, B; Gostner, J; Hermann, M; Jenny, M; Maglione, M; Margreiter, R; Oberhuber, R; Obrist, P; Pratschke, J; Watschinger, K; Werner, ER1
Hattori, Y; Hayakawa, H; Hirata, Y; Kakoki, M; Kikuchi, K; Nagano, T; Nagata, D; Nakanishi, N; Nishimatsu, H; Omata, M; Suzuki, E; Tojo, A1

Other Studies

10 other study(ies) available for sapropterin and Ischemia

ArticleYear
Tetrahydrobiopterin prevents chronic ischemia-related lower urinary tract dysfunction through the maintenance of nitric oxide bioavailability.
    Scientific reports, 2020, 11-16, Volume: 10, Issue:1

    Topics: Animals; Biological Availability; Biopterins; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Ischemia; Male; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Tetrahydrofolate Dehydrogenase; Urinary Bladder

2020
Administration of Tetrahydrobiopterin (BH4) Protects the Renal Microcirculation From Ischemia and Reperfusion Injury.
    Anesthesia and analgesia, 2017, Volume: 125, Issue:4

    Topics: Animals; Biopterins; Female; Ischemia; Kidney; Microcirculation; Protective Agents; Random Allocation; Renal Circulation; Reperfusion Injury; Sheep

2017
In Response.
    Anesthesia and analgesia, 2018, Volume: 126, Issue:3

    Topics: Animals; Biopterins; Ischemia; Sheep

2018
The Unknown Mechanism of Exogenous Tetrahydrobiopterin in the Renal Protection of Sheep Ischemia and Reperfusion.
    Anesthesia and analgesia, 2018, Volume: 126, Issue:3

    Topics: Animals; Biopterins; Ischemia; Kidney; Microcirculation; Reperfusion Injury; Sheep

2018
Depletion of NADP(H) due to CD38 activation triggers endothelial dysfunction in the postischemic heart.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Sep-15, Volume: 112, Issue:37

    Topics: ADP-ribosyl Cyclase 1; Animals; Biopterins; Coronary Artery Disease; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Heart; Hypoxia; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADP; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Small Interfering

2015
Oral tetrahydrobiopterin improves the beneficial effect of adenoviral-mediated eNOS gene transfer after induction of hindlimb ischemia.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2010, Volume: 18, Issue:8

    Topics: Adenoviridae; Animals; Biopterins; Blotting, Western; Glutathione; Immunohistochemistry; Ischemia; Lower Extremity; Male; Muscle, Skeletal; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley

2010
Tetrahydrobiopterin, L-arginine and vitamin C actsynergistically to decrease oxidative stress, increase nitricoxide and improve blood flow after induction of hindlimbischemia in the rat.
    Molecular medicine (Cambridge, Mass.), 2012, May-09, Volume: 18

    Topics: Administration, Oral; Animals; Antioxidants; Arginine; Ascorbic Acid; Biopterins; Calcium; Drug Synergism; Enzyme Activation; Hindlimb; Ischemia; Male; Muscle, Skeletal; Necrosis; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Regional Blood Flow

2012
Prevention of lethal murine pancreas ischemia reperfusion injury is specific for tetrahydrobiopterin.
    Transplant international : official journal of the European Society for Organ Transplantation, 2012, Volume: 25, Issue:10

    Topics: Animals; Antioxidants; Ascorbic Acid; Biopterins; Cold Ischemia; Immunohistochemistry; Ischemia; Liver; Male; Mice; Mice, Inbred C57BL; Microcirculation; Microscopy, Confocal; Nitric Oxide; Organ Preservation; Pancreas; Pancreas Transplantation; Reperfusion Injury; Tetrahydrofolates; Time Factors

2012
Tetrahydrobiopterin, L-arginine and vitamin C act synergistically to decrease oxidant stress and increase nitric oxide that increases blood flow recovery after hindlimb ischemia in the rat.
    Molecular medicine (Cambridge, Mass.), 2012, Oct-24, Volume: 18

    Topics: Administration, Oral; Animals; Arginine; Ascorbic Acid; Biopterins; Calcium; Drug Synergism; Hindlimb; Ischemia; Male; Models, Biological; Muscles; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Recovery of Function; Regional Blood Flow

2012
Effects of tetrahydrobiopterin on endothelial dysfunction in rats with ischemic acute renal failure.
    Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:2

    Topics: Acute Kidney Injury; Animals; Biopterins; Endothelium, Vascular; Ischemia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Renal Circulation; Reperfusion Injury

2000