sapropterin has been researched along with Diabetic Glomerulosclerosis in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Channon, KM; Kashihara, N; Kidokoro, K; Sasaki, T; Satoh, M; Yada, T | 1 |
| Guo, H; Nie, Y; Wang, J; Yang, Q; Yin, X; Zhang, F; Zhou, X | 1 |
| Arakawa, S; Fujimoto, S; Haruna, Y; Horike, H; Kashihara, N; Namikoshi, T; Sasaki, T; Satoh, M; Yada, T | 1 |
| Arellano-Mendoza, MG; Castorena-Torres, F; Coronel, I; del Valle-Mondragon, L; Escalante, B; Rios, A; Romo, E; Vargas-Robles, H | 1 |
| Chuang, LY; Guh, JY; Huang, JS; Lee, YH; Liao, YC; Shi, MD | 1 |
| Imanishi, M; Kitabayashi, C; Konishi, Y; Maeda, I; Masada, M; Morikawa, T; Nishiyama, A; Okada, N; Shirahashi, N; Wilcox, CS | 1 |
| Arakawa, S; Fujimoto, S; Haruna, Y; Horike, H; Kashihara, N; Komai, N; Makino, H; Sasaki, T; Satoh, M; Tsujioka, K | 1 |
| Hosoi, M; Imanishi, M; Konishi, Y; Masada, M; Miura, K; Morikawa, T; Okada, N; Okumura, M; Shintaku, H; Yoshida, Y | 1 |
| Prabhakar, SS | 1 |
1 trial(s) available for sapropterin and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Angiotensin II receptor blockade reduces salt sensitivity of blood pressure through restoration of renal nitric oxide synthesis in patients with diabetic nephropathy.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Albuminuria; Angiotensin Receptor Antagonists; Biopterins; Blood Pressure; Deoxyguanosine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Hemodynamics; Humans; Kidney; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Receptors, Angiotensin; Sodium Chloride, Dietary; Tetrazoles; Valine; Valsartan | 2013 |
8 other study(ies) available for sapropterin and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Maintenance of endothelial guanosine triphosphate cyclohydrolase I ameliorates diabetic nephropathy.
Topics: Albuminuria; Animals; Biopterins; Cell Line; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Endothelium, Vascular; GTP Cyclohydrolase; Humans; Metformin; Mice; Nitric Oxide Synthase Type III; Reactive Oxygen Species | 2013 |
Tetrahydrobiopterin contributes to the proliferation of mesangial cells and accumulation of extracellular matrix in early-stage diabetic nephropathy.
Topics: Animals; Biopterins; Cell Proliferation; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Extracellular Matrix; Kidney Cortex; Kidney Function Tests; Laminin; Male; Mesangial Cells; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Sugar Acids | 2017 |
Angiotensin II type 1 receptor blocker ameliorates uncoupled endothelial nitric oxide synthase in rats with experimental diabetic nephropathy.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Base Sequence; Biopterins; Diabetes Mellitus, Experimental; Diabetic Nephropathies; DNA Primers; GTP Cyclohydrolase; Kidney Glomerulus; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger | 2008 |
L-arginine and antioxidant diet supplementation partially restores nitric oxide-dependent regulation of phenylephrine renal vasoconstriction in diabetics rats.
Topics: Animals; Antioxidants; Arginine; Ascorbic Acid; Biopterins; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Enzyme Inhibitors; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides; Vasoconstriction; Vasoconstrictor Agents; Vitamin E | 2010 |
Advanced glycation end products-mediated hypertrophy is negatively regulated by tetrahydrobiopterin in renal tubular cells.
Topics: Actins; Biopterins; Cell Enlargement; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Diabetic Nephropathies; Gene Expression Regulation; Glycation End Products, Advanced; GTP Cyclohydrolase; Humans; Janus Kinase 2; Kidney Tubules; Nitric Oxide; Nitric Oxide Synthase Type II; Pterins; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Sugar Acids | 2012 |
NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy.
Topics: Animals; Antioxidants; Biopterins; Diabetic Nephropathies; Gene Expression Regulation, Enzymologic; Kidney Glomerulus; Male; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxides; Tyrosine | 2005 |
Decrease in tetrahydrobiopterin as a possible cause of nephropathy in type II diabetic rats.
Topics: Animals; Biopterins; Blood Glucose; Blood Pressure; Body Weight; Calcium Channel Blockers; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dihydropyridines; Kidney; Male; Nitric Oxide; Proteinuria; Rats; Rats, Inbred OLETF; Rats, Long-Evans | 2006 |
Tetrahydrobiopterin reverses the inhibition of nitric oxide by high glucose in cultured murine mesangial cells.
Topics: Animals; Arginine; Ascorbic Acid; Biopterins; Cell Division; Cells, Cultured; Diabetic Nephropathies; Enzyme Induction; Glomerular Mesangium; Glucose; Mice; Models, Chemical; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II | 2001 |