sapropterin has been researched along with Diabetic Angiopathies in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, H; El-Daly, M; Hirota, SA; Hollenberg, MD; Pulakazhi Venu, VK; Saifeddine, M; Triggle, CR | 1 |
| Arrick, DM; Mayhan, WG | 1 |
| Ding, H; Triggle, CR | 1 |
| Nygren, A; Nyström, T; Sjöholm, A | 1 |
| Hayashi, T; Iguchi, A | 1 |
| Bauersachs, J; Brandt, M; Closs, E; Daiber, A; Ertl, G; Förstermann, U; Münzel, T; Oelze, M; Thum, T; Wenzel, P; Xu, J; Zou, MH | 1 |
| Bauersachs, J; Thum, T | 1 |
2 review(s) available for sapropterin and Diabetic Angiopathies
| Article | Year |
|---|---|
Endothelial dysfunction in diabetes: multiple targets for treatment.
Topics: Animals; Biological Factors; Biopterins; Blood Glucose; Calcium; Cell Communication; Connexins; Diabetes Mellitus; Diabetic Angiopathies; Dyslipidemias; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Humans; Hypercalcemia; Hyperglycemia; Hypertension; Nitric Oxide Synthase Type III; Oxidative Stress; Transient Receptor Potential Channels | 2010 |
[Diabetic macroangiopathy and NO].
Topics: Animals; Biopterins; Diabetic Angiopathies; Endothelium, Vascular; Estrogens; Female; Free Radicals; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Reactive Oxygen Species; Risk Factors; Sex Characteristics | 2004 |
1 trial(s) available for sapropterin and Diabetic Angiopathies
| Article | Year |
|---|---|
Tetrahydrobiopterin increases insulin sensitivity in patients with type 2 diabetes and coronary heart disease.
Topics: Biopterins; Blood Glucose; Coenzymes; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Male; Matched-Pair Analysis; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Reference Values; Vasodilation | 2004 |
4 other study(ies) available for sapropterin and Diabetic Angiopathies
| Article | Year |
|---|---|
Minimizing Hyperglycemia-Induced Vascular Endothelial Dysfunction by Inhibiting Endothelial Sodium-Glucose Cotransporter 2 and Attenuating Oxidative Stress: Implications for Treating Individuals With Type 2 Diabetes.
Topics: Biomarkers; Biopterins; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Humans; Hyperglycemia; Incidence; Isothiocyanates; Oxidative Stress; Prognosis; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Sulfoxides | 2019 |
Tetrahydrobiopterin rescues impaired responses of cerebral resistance arterioles during type 1 diabetes.
Topics: Animals; Arterioles; Biopterins; Cerebral Cortex; Cerebrovascular Circulation; Cerebrovascular Disorders; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Dose-Response Relationship, Drug; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Pia Mater; Rats, Sprague-Dawley; Superoxides; Vascular Resistance; Vasodilation; Vasodilator Agents | 2017 |
Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus.
Topics: Animals; Atorvastatin; Biopterins; Body Weight; Cell Adhesion Molecules; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; GTP Cyclohydrolase; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intramolecular Oxidoreductases; Male; Microfilament Proteins; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphoproteins; Pyrroles; Rats; Rats, Wistar; Stem Cells; Tetrahydrofolate Dehydrogenase; Vasodilation | 2008 |
Letter by Thum et al regarding article, "Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: restoration by the peroxisome proliferator-activated receptor-gamma agonist
Topics: Biopterins; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelial Cells; Humans; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; PPAR gamma; Rosiglitazone; Stem Cells; Thiazolidinediones; Vasodilator Agents | 2008 |