sapropterin has been researched along with Depressive Disorder in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McHugh, PC | 1 |
| Kitagami, T; Miura, H; Ohta, T; Ozaki, N; Qiao, H | 1 |
| Angst, J; Curtius, HC; Levine, RA; Lovenberg, W; Niederwieser, A; Woggon, B | 1 |
| Ballenger, JC; Gold, PW; Kellner, CH; Post, RM; Rakita, RM; Rubinow, DA | 1 |
| Angst, J; Curtius, HC; Niederwieser, A; Woggon, B | 1 |
| Davidson, JR; Duch, DS; Garbutt, JC; Nichol, CA; Woolf, JH | 1 |
| Curtius, HC; Levine, R; Müldner, H; Niederwieser, A | 1 |
| Abou-Saleh, MT; Anderson, DN; Blair, JA; Wilkinson, AM | 1 |
| Hashimoto, R; Mizutani, M; Nagatsu, T; Nakazawa, K; Ohta, T | 1 |
| Hirayama, K; Kapatos, G; Lentz, SI; Stegenga, S; Zhu, M | 1 |
| Goto, S; Hashimoto, R; Kitagami, T; Miura, H; Mizutani, M; Ohta, T; Omura, I | 1 |
| Meltzer, HY | 1 |
| Hashimoto, R; Kaneda, N; Kasahara, Y; Nagatsu, T; Ohta, T; Ozaki, N | 1 |
| Irwin, M; Knapp, S | 1 |
2 review(s) available for sapropterin and Depressive Disorder
| Article | Year |
|---|---|
Differential metabolism of tetrahydrobiopterin in monoamine neurons: a hypothesis based upon clinical and basic research.
Topics: Animals; Biogenic Monoamines; Biopterins; Brain; Depressive Disorder; Humans; Hypothalamus; Mesencephalon; Nervous System Diseases; Neurons | 1993 |
Beyond serotonin.
Topics: Adenylate Kinase; Antidepressive Agents; Biopterins; Depressive Disorder; gamma-Aminobutyric Acid; Humans; Phototherapy; Protein Kinases; Receptors, Serotonin; Serotonin | 1991 |
1 trial(s) available for sapropterin and Depressive Disorder
| Article | Year |
|---|---|
Unsuccessful treatment of depression with tetrahydrobiopterin.
Topics: Biopterins; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Electroconvulsive Therapy; Female; Humans; Pteridines | 1984 |
11 other study(ies) available for sapropterin and Depressive Disorder
| Article | Year |
|---|---|
The tetrahydrobiopterin pathway: a novel target for the treatment of depression.
Topics: Antidepressive Agents; Biopterins; Depressive Disorder; Humans; Metabolic Networks and Pathways; Norepinephrine; Pteridines; Serotonin | 2011 |
Fluvoxamine, a selective serotonin reuptake inhibitor, suppresses tetrahydrobiopterin levels and dopamine as well as serotonin turnover in the mesoprefrontal system of mice.
Topics: Animals; Biopterins; Depressive Disorder; Dopamine; Fluvoxamine; Housing, Animal; Injections, Subcutaneous; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Prefrontal Cortex; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Social Isolation | 2005 |
Successful treatment of depression with tetrahydrobiopterin.
Topics: Biogenic Amines; Biopterins; Depressive Disorder; Female; Humans; Middle Aged; Pteridines | 1983 |
Tetrahydrobiopterin levels in cerebrospinal fluid of affectively ill patients.
Topics: Adult; Aged; Biopterins; Depressive Disorder; Humans; Middle Aged; Pteridines | 1983 |
Urinary excretion of biopterin and neopterin in psychiatric disorders.
Topics: Adult; Biopterins; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Middle Aged; Neopterin; Pteridines; Schizophrenia | 1984 |
Therapeutic efficacy of tetrahydrobiopterin in Parkinson's disease.
Topics: Aged; Antidepressive Agents; Antiparkinson Agents; Biopterins; Brain; Depressive Disorder; Drug Evaluation; Female; Humans; Male; Middle Aged; Parkinson Disease; Phenylalanine Hydroxylase; Phenylketonurias; Pteridines | 1984 |
Recovery from depression after electroconvulsive therapy is accompanied by evidence of increased tetrahydrobiopterin-dependent hydroxylation.
Topics: Aged; Biopterins; Depressive Disorder; Electroconvulsive Therapy; Energy Intake; Humans; Hydroxylation; Middle Aged; Phenylalanine | 1994 |
Changes in plasma tetrahydrobiopterin levels of depressives in depressive and remission phases: reconfirmed by measurement with an internal standard.
Topics: Adult; Biopterins; Chromatography, High Pressure Liquid; Depressive Disorder; Humans; Psychiatric Status Rating Scales; Reference Standards | 1994 |
Plasma biopterin levels and depressive state in pregnancy and the early puerperal period.
Topics: Adult; Biomarkers; Biopterins; Depression, Postpartum; Depressive Disorder; Female; Humans; Pregnancy; Pregnancy Complications | 2002 |
The plasma tetrahydrobiopterin levels in patients with affective disorders.
Topics: Adult; Biopterins; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Middle Aged; Personality Inventory | 1990 |
Plasma levels of tetrahydrobiopterin and folate in major depression.
Topics: Adult; Biopterins; Depressive Disorder; Folic Acid; Humans; Male; Middle Aged; Radioimmunoassay; Vitamin B 12 | 1989 |