sapropterin has been researched along with Coronary Artery Disease in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Mohanty, S; Rai, S; Ramakrishnan, L; Roy, A; Sen, A; Singh, A; Thakkar, H; Vincent, V | 1 |
| Kalaivani, M; Mohanty, S; Naik, N; Ramakrishnan, L; Roy, A; Sen, A; Singh, A | 1 |
| Engineer, A; Feng, Q; Kim, MY; Lim, YJ; Lu, X; Norozi, K | 1 |
| Anderson, EJ; Dawkins, JT; Hickner, RC; La Favor, JD; Wingard, CJ | 1 |
| Ambrosio, G; Boslett, J; De Pascali, F; Druhan, LJ; El-Mahdy, M; Hemann, C; Reyes, LA; Varadharaj, S; Zweier, JL | 1 |
| Alp, NJ; Antoniades, C; Channon, KM; Costigan, M; Cunnington, C; Diesch, J; Guzik, TJ; Leeson, P; Lötsch, J; Shirodaria, C; Stefanadis, C; Tegeder, I; Tousoulis, D; Van Assche, T; Woolf, CJ | 1 |
| Böhm, F; Channon, KM; Malmström, RE; Pernow, J; Settergren, M | 1 |
| Antoniades, C; Antonopoulos, AS; Bakogiannis, C; Bendall, J; Casadei, B; Channon, KM; Demosthenous, M; Guzik, TJ; Hale, A; Leeson, P; Marinou, K; Paschalis, A; Psarros, C; Stefanadis, C; Tousoulis, D; Triantafyllou, C; Zhang, MH | 1 |
| Antoniades, C; Cerrato, R; Channon, KM; Choudhury, RP; Crabtree, MJ; Cunnington, C; Francis, JM; Kylintireas, I; Lee, JM; Lee, R; Lindsay, AC; Margaritis, M; Neubauer, S; Pillai, R; Ratnatunga, C; Sayeed, R; Shirodaria, C; Van Assche, T | 1 |
| Antoniades, C; Cai, S; Channon, KM; de Bono, J; Lee, J; Leeson, P; Neubauer, S; Pillai, R; Ratnatunga, C; Refsum, H; Shirodaria, C; Warrick, N | 1 |
| Lüscher, TF; Noll, G; Spieker, LE | 1 |
1 review(s) available for sapropterin and Coronary Artery Disease
| Article | Year |
|---|---|
Current strategies and perspectives for correcting endothelial dysfunction in atherosclerosis.
Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Arginine; Aspirin; Biopterins; Calcium Channel Blockers; Coronary Artery Disease; Endothelins; Endothelium, Vascular; Folic Acid; Hormone Replacement Therapy; Humans; Nitrates; Nitric Oxide; Nitric Oxide Synthase | 2001 |
4 trial(s) available for sapropterin and Coronary Artery Disease
| Article | Year |
|---|---|
L-arginine and tetrahydrobiopterin protects against ischemia/reperfusion-induced endothelial dysfunction in patients with type 2 diabetes mellitus and coronary artery disease.
Topics: Aged; Arginine; Biopterins; Blood Flow Velocity; Cardiovascular Agents; Coronary Artery Disease; Cross-Over Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelium, Vascular; Female; Forearm; Humans; Infusions, Intra-Arterial; Male; Regional Blood Flow; Reperfusion Injury; Treatment Outcome; Vasodilation; Vasodilator Agents | 2009 |
Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin-mediated endothelial nitric oxide synthase coupling.
Topics: Aged; Atorvastatin; Biological Availability; Biopterins; Coronary Artery Bypass; Coronary Artery Disease; Coronary Vessels; Double-Blind Method; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxidative Coupling; Oxygen; Pyrroles; Superoxides | 2011 |
Systemic and vascular oxidation limits the efficacy of oral tetrahydrobiopterin treatment in patients with coronary artery disease.
Topics: Administration, Oral; Aged; Biopterins; Coronary Artery Disease; Double-Blind Method; Endothelium, Vascular; Female; Humans; Male; Oxidation-Reduction; Treatment Outcome | 2012 |
5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling.
Topics: Acetylcholine; Antioxidants; Atherosclerosis; Biological Availability; Biopterins; Bradykinin; Coronary Artery Bypass; Coronary Artery Disease; Double-Blind Method; Endothelium, Vascular; Homocysteine; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Protein Binding; Superoxides; Tetrahydrofolates | 2006 |
6 other study(ies) available for sapropterin and Coronary Artery Disease
| Article | Year |
|---|---|
Endothelial colony forming cells' tetrahydrobiopterin level in coronary artery disease patients and its association with circulating endothelial progenitor cells.
Topics: Biopterins; Coronary Artery Disease; Endothelial Progenitor Cells; Humans | 2022 |
Role of endothelial colony forming cells (ECFCs) Tetrahydrobiopterin (BH4) in determining ECFCs functionality in coronary artery disease (CAD) patients.
Topics: Biopterins; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Survival; Coronary Artery Disease; Endothelial Cells; Neovascularization, Physiologic; Oxidative Stress; Stem Cells; Wound Healing | 2022 |
Sapropterin reduces coronary artery malformation in offspring of pregestational diabetes mice.
Topics: Administration, Oral; Animals; Antioxidants; Biopterins; Coronary Artery Disease; Coronary Vessels; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Female; Hypoglycemic Agents; Mice; Mice, Inbred C57BL; Pregnancy; Streptozocin | 2020 |
Exercise prevents Western diet-associated erectile dysfunction and coronary artery endothelial dysfunction: response to acute apocynin and sepiapterin treatment.
Topics: Acetophenones; Animals; Biopterins; Coronary Artery Disease; Coronary Vessels; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Erectile Dysfunction; Exercise Therapy; Male; NADPH Oxidases; Obesity; Oxidative Stress; Penile Erection; Pterins; Rats; Rats, Sprague-Dawley; Sedentary Behavior; Time Factors; Vasodilation; Vasodilator Agents | 2013 |
Depletion of NADP(H) due to CD38 activation triggers endothelial dysfunction in the postischemic heart.
Topics: ADP-ribosyl Cyclase 1; Animals; Biopterins; Coronary Artery Disease; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Heart; Hypoxia; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADP; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Small Interfering | 2015 |
GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function.
Topics: Aged; Biopterins; Coronary Artery Disease; Endothelium, Vascular; Female; Genetic Variation; GTP Cyclohydrolase; Haplotypes; Humans; Male; Mammary Arteries; Multivariate Analysis; Nitric Oxide; Nitric Oxide Synthase Type III; Saphenous Vein; Superoxides | 2008 |