sapropterin has been researched along with Cardiovascular Stroke in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ebner, A; Heidrich, FM; Jercke, MC; Pfluecke, C; Poitz, DM; Quick, S; Ritzkat, A; Simonis, G; Speiser, U; Strasser, RH; Wäßnig, NK; Wiedemann, S | 1 |
| Abad, E; Garcia-Dorado, D; Hernando, V; Inserte, J; Poncelas-Nozal, M; Vilardosa, Ú | 1 |
| Sun, J; Talukder, MA; Varadharaj, S; Xie, L; Zweier, JL | 1 |
| Baumgardt, SL; Bosnjak, ZJ; Fang, J; Ge, ZD; Kersten, JR; Leucker, TM; Paterson, M; Warltier, DC; Zhang, DX | 1 |
| Hirata, K; Kawashima, S; Masano, T; Sasaki, N; Satomi-Kobayashi, S; Shinohara, M; Takaya, T; Takeda, M; Tawa, H; Toh, R; Yamashita, T; Yokoyama, M | 1 |
| Boontje, NM; de Crom, R; de Waard, MC; Dekkers, DH; Duncker, DJ; Kuster, DW; Lamers, JM; van der Velden, J; van Haperen, R | 1 |
| Ge, ZD; Hirata, N; Ionova, IA; Kersten, JR; Pieper, GM; Pratt, PF; Pravdic, D; Vásquez-Vivar, J; Vladic, N; Warltier, DC | 1 |
| Fujita, M; Iwasaka, T; Okazaki, T; Otani, H; Shimazu, T; Yoshioka, K | 1 |
| Brzezinska, AK; Du, JH; Ge, ZD; Kersten, JR; Leucker, T; Pratt, PF; Shi, Y; Vladic, N; Warltier, DC | 1 |
| Hiroi, T; Ishii, M; Kiuchi, Y; Shimizu, S; Wajima, T | 1 |
| Akasaka, T; Kaji, S; Kajiya, F; Mochizuki, S; Ogasawara, Y; Tanemoto, K; Yada, T; Yoshida, K | 1 |
11 other study(ies) available for sapropterin and Cardiovascular Stroke
| Article | Year |
|---|---|
The endothelial nitric oxide synthase cofactor tetrahydrobiopterin shields the remote myocardium from apoptosis after experimental myocardial infarction in vivo.
Topics: Animals; Apoptosis; Biopterins; Cardiotonic Agents; Coronary Vessels; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type III; Rats, Wistar | 2017 |
Activation of cGMP/protein kinase G pathway in postconditioned myocardium depends on reduced oxidative stress and preserved endothelial nitric oxide synthase coupling.
Topics: Animals; Biopterins; Cell Death; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Ischemic Postconditioning; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxides; Time Factors; Tyrosine | 2013 |
Liposomal tetrahydrobiopterin preserves eNOS coupling in the post-ischemic heart conferring in vivo cardioprotection.
Topics: Animals; Biopterins; Cardiotonic Agents; Heart; Humans; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Reactive Oxygen Species | 2015 |
Chronic Co-Administration of Sepiapterin and L-Citrulline Ameliorates Diabetic Cardiomyopathy and Myocardial Ischemia/Reperfusion Injury in Obese Type 2 Diabetic Mice.
Topics: Age Factors; Animals; Biopterins; Cardiotonic Agents; Cells, Cultured; Citrulline; Coronary Circulation; Coronary Vessels; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Endothelial Cells; Isolated Heart Preparation; Mice, Inbred C57BL; Mice, Obese; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; Phosphorylation; Protein Multimerization; Pterins; Time Factors; Vasodilation; Ventricular Function, Left | 2016 |
Beneficial effects of exogenous tetrahydrobiopterin on left ventricular remodeling after myocardial infarction in rats: the possible role of oxidative stress caused by uncoupled endothelial nitric oxide synthase.
Topics: Animals; Biopterins; Male; Myocardial Infarction; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxides; Ventricular Remodeling | 2008 |
Detrimental effect of combined exercise training and eNOS overexpression on cardiac function after myocardial infarction.
Topics: Acetylcysteine; Actin Cytoskeleton; Animals; Antioxidants; Arginine; Biopterins; Disease Models, Animal; Exercise Therapy; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Myocardial Infarction; Myocardium; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Physical Exertion; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Superoxides; Time Factors; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Pressure; Ventricular Remodeling | 2009 |
Cardiac-specific overexpression of GTP cyclohydrolase 1 restores ischaemic preconditioning during hyperglycaemia.
Topics: Analysis of Variance; Animals; Biopterins; Calcium; Disease Models, Animal; Enzyme Inhibitors; GTP Cyclohydrolase; Humans; Hyperglycemia; Ischemic Preconditioning, Myocardial; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Signal Transduction; Time Factors; Ultrasonography; Ventricular Function, Left | 2011 |
Sepiapterin enhances angiogenesis and functional recovery in mice after myocardial infarction.
Topics: Administration, Oral; Angiogenesis Inducing Agents; Animals; Biopterins; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; GTP Cyclohydrolase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pterins; Recovery of Function; Stroke Volume; Time Factors; Tyrosine; Ultrasonography; Ventricular Function, Left | 2011 |
Decreased tetrahydrobiopterin and disrupted association of Hsp90 with eNOS by hyperglycemia impair myocardial ischemic preconditioning.
Topics: Animals; Benzoquinones; Biopterins; Blood Glucose; Blotting, Western; Cells, Cultured; Coronary Occlusion; Disease Models, Animal; Endothelial Cells; HSP90 Heat-Shock Proteins; Hyperglycemia; Immunoprecipitation; Ischemic Preconditioning, Myocardial; Lactams, Macrocyclic; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Protein Multimerization; Pterins; Rabbits; Time Factors | 2011 |
Reduction of myocardial infarct size by tetrahydrobiopterin: possible involvement of mitochondrial KATP channels activation through nitric oxide production.
Topics: Animals; Anti-Arrhythmia Agents; Arginine; Biopterins; Cyclic GMP; Decanoic Acids; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxy Acids; Male; Malondialdehyde; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Potassium Channels; Rats; Rats, Sprague-Dawley | 2006 |
Changes of asymmetric dimethylarginine, nitric oxide, tetrahydrobiopterin, and oxidative stress in patients with acute myocardial infarction by medical treatments.
Topics: Adult; Aged; Arginine; Biopterins; Case-Control Studies; Drug Therapy; Endothelium, Vascular; Female; Humans; Lipoproteins, LDL; Male; Middle Aged; Myocardial Infarction; Nitric Oxide; Oxidative Stress; Superoxides | 2007 |