sapropterin has been researched along with Cardiomegaly in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bendall, JK; Channon, KM; Crabtree, MJ; Douglas, G; McNeill, E | 1 |
| Delgado, C; Ruiz-Hurtado, G | 1 |
| Hiroi, T; Ishibashi, M; Ishii, M; Kiuchi, Y; Kumagai, S; Kurihara, T; Shimizu, S; Wajima, T | 1 |
| Madeddu, P | 1 |
| Hashikabe, Y; Hattori, Y; Kase, H; Nakanishi, N; Uchida, K | 1 |
| Alp, NJ; Bedja, D; Biswal, S; Chakir, K; Champion, HC; Channon, KM; Cormaci, G; Gabrielson, K; Halushka, MK; Kass, DA; Ketner, EA; Majmudar, M; Mitchell, JB; Moens, AL; Paolocci, N; Takimoto, E; Tocchetti, CG; Wolin, MS | 1 |
2 review(s) available for sapropterin and Cardiomegaly
| Article | Year |
|---|---|
Tetrahydrobiopterin in cardiovascular health and disease.
Topics: Atherosclerosis; Biopterins; Cardiomegaly; Cardiovascular Diseases; Cardiovascular System; Humans; Inflammation; Nitric Oxide Synthase Type III; Oxidation-Reduction | 2014 |
Nitric oxide pathway in hypertrophied heart: new therapeutic uses of nitric oxide donors.
Topics: Arginine; Biopterins; Cardiomegaly; Cyclic GMP; Humans; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase | 2010 |
4 other study(ies) available for sapropterin and Cardiomegaly
| Article | Year |
|---|---|
Decreased cardiac mitochondrial tetrahydrobiopterin in a rat model of pressure overload.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Arterial Pressure; Biopterins; Cardiomegaly; Disease Models, Animal; Fibrosis; Hypertension; Male; Mitochondria, Heart; Myocardium; Myocytes, Cardiac; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger | 2013 |
Correction of endothelial dysfunction by tetrahydrobiopterin: new hope for the treatment of arterial hypertension?
Topics: Angiotensin II; Animals; Antioxidants; Biopterins; Cardiomegaly; Endothelium, Vascular; Hypertension; Immunohistochemistry; Male; Myocardium; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxides; Tyrosine; Up-Regulation | 2005 |
Supplementation with tetrahydrobiopterin prevents the cardiovascular effects of angiotensin II-induced oxidative and nitrosative stress.
Topics: Acetophenones; Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Biopterins; Cardiomegaly; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Immunohistochemistry; Male; NADPH Oxidases; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxides; Time Factors; Tyrosine; Up-Regulation | 2005 |
Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy.
Topics: Animals; Biopterins; Cardiomegaly; Cyclic N-Oxides; Disease Models, Animal; Fibrosis; Gene Expression Profiling; GTP Cyclohydrolase; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Nitric Oxide Synthase Type III; Spin Labels | 2008 |