Page last updated: 2024-08-21

sapropterin and Cardiac Remodeling, Ventricular

sapropterin has been researched along with Cardiac Remodeling, Ventricular in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's5 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujita, M; Iwasaka, T; Otani, H; Shimazu, T; Shiojima, I; Yoshioka, K1
Bedja, D; Carnicer, R; Casadei, B; Channon, KM; Duglan, D; Hahn, VS; Hashimoto, T; Kass, DA; Recalde, A; Sivakumaran, V; Zhu, G1
Hirata, K; Kawashima, S; Masano, T; Sasaki, N; Satomi-Kobayashi, S; Shinohara, M; Takaya, T; Takeda, M; Tawa, H; Toh, R; Yamashita, T; Yokoyama, M1
Boontje, NM; de Crom, R; de Waard, MC; Dekkers, DH; Duncker, DJ; Kuster, DW; Lamers, JM; van der Velden, J; van Haperen, R1
Arkenbout, EK; Barker, N; Barouch, LA; Bedja, D; Champion, HC; Channon, KM; Chen, J; Cingolani, O; Gabrielson, KL; Hale, AB; Halushka, MK; Kaminski, PM; Kass, DA; Leyton-Mange, JS; Moens, AL; Niu, X; Wolin, MS; Wuyts, FL; Xia, Y; Yang, R1
Gielis, JF; Lin, JY; Moens, AL; Schmidt, HH; Van Schil, PE; Wingler, K1
Chen, AF; Groban, L; Jessup, JA; Kim-Shapiro, DB; Presley, TD; Wang, H; Zhang, L1
Alp, NJ; Channon, KM; Kass, DA; Ketner, EA; Moens, AL; O'Neill, CA; Schmidt, TS; Takimoto, E; Wolin, MS1

Reviews

1 review(s) available for sapropterin and Cardiac Remodeling, Ventricular

ArticleYear
Pathogenetic role of eNOS uncoupling in cardiopulmonary disorders.
    Free radical biology & medicine, 2011, Apr-01, Volume: 50, Issue:7

    Topics: Arginine; Atherosclerosis; Biopterins; Blood Pressure; Cardiac Surgical Procedures; Cell Adhesion; Endothelium, Vascular; Folic Acid; Humans; Hypertension, Pulmonary; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxygen; Reactive Oxygen Species; Vasodilation; Ventricular Remodeling

2011

Other Studies

7 other study(ies) available for sapropterin and Cardiac Remodeling, Ventricular

ArticleYear
Sepiapterin prevents left ventricular hypertrophy and dilatory remodeling induced by pressure overload in rats.
    American journal of physiology. Heart and circulatory physiology, 2015, Nov-15, Volume: 309, Issue:10

    Topics: Animals; Aorta; Biopterins; Capillaries; Cell Size; Constriction; Dilatation, Pathologic; Enzyme Inhibitors; Glycine; Heart; Hypertrophy, Left Ventricular; Male; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Oxidative Stress; Pressure; Pterins; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Ultrasonography; Ventricular Dysfunction, Left; Ventricular Remodeling

2015
Tetrahydrobiopterin Protects Against Hypertrophic Heart Disease Independent of Myocardial Nitric Oxide Synthase Coupling.
    Journal of the American Heart Association, 2016, Mar-21, Volume: 5, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Biopterins; Cardiovascular Agents; Cytokines; Cytoprotection; Disease Models, Animal; GTP Cyclohydrolase; Humans; Hypertrophy, Left Ventricular; Inflammation Mediators; Macrophages; Mice, Transgenic; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Signal Transduction; Superoxides; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2016
Beneficial effects of exogenous tetrahydrobiopterin on left ventricular remodeling after myocardial infarction in rats: the possible role of oxidative stress caused by uncoupled endothelial nitric oxide synthase.
    Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:9

    Topics: Animals; Biopterins; Male; Myocardial Infarction; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxides; Ventricular Remodeling

2008
Detrimental effect of combined exercise training and eNOS overexpression on cardiac function after myocardial infarction.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Acetylcysteine; Actin Cytoskeleton; Animals; Antioxidants; Arginine; Biopterins; Disease Models, Animal; Exercise Therapy; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Myocardial Infarction; Myocardium; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Physical Exertion; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Superoxides; Time Factors; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Pressure; Ventricular Remodeling

2009
Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the beta3-adrenoreceptor.
    Journal of molecular and cellular cardiology, 2009, Volume: 47, Issue:5

    Topics: Age Factors; Animals; Biopterins; Blotting, Western; Cardiomyopathies; Echocardiography; Hypertrophy, Left Ventricular; Male; Mice; Mice, Mutant Strains; Nitric Oxide Synthase; Oxidative Stress; Receptors, Adrenergic, beta-3; Superoxides; Vasoconstriction; Ventricular Remodeling

2009
Tetrahydrobiopterin restores diastolic function and attenuates superoxide production in ovariectomized mRen2.Lewis rats.
    Endocrinology, 2011, Volume: 152, Issue:6

    Topics: Animals; Biopterins; Diastole; Disease Models, Animal; Female; Heart; Heart Diseases; Humans; Myocardium; Nitric Oxide Synthase Type I; Ovariectomy; Postmenopause; Rats; Rats, Inbred Lew; Superoxides; Ventricular Remodeling

2011
Bi-modal dose-dependent cardiac response to tetrahydrobiopterin in pressure-overload induced hypertrophy and heart failure.
    Journal of molecular and cellular cardiology, 2011, Volume: 51, Issue:4

    Topics: Analysis of Variance; Animals; Biopterins; Cardiotonic Agents; Dose-Response Relationship, Drug; Heart Failure; Humans; Hypertrophy, Left Ventricular; Ligation; Mice; Mice, Inbred C57BL; Myocardium; Random Allocation; Superoxides; Ventricular Function, Left; Ventricular Remodeling

2011