Compounds > sapropterin
Page last updated: 2024-08-21

sapropterin and Autoimmune Diabetes

sapropterin has been researched along with Autoimmune Diabetes in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Channon, KM; Chen, AF; Chen, DD; Chen, LY; Tie, L; Xie, HH1
Arrick, DM; Mayhan, WG1
Chen, AF; Yang, XQ1
Casarini, DE; Colucci, JA; Fernandes, FB; Marco, GS; Schor, N; Vio, CP1
Bauersachs, J; Brandt, M; Closs, E; Daiber, A; Ertl, G; Förstermann, U; Münzel, T; Oelze, M; Thum, T; Wenzel, P; Xu, J; Zou, MH1

Other Studies

5 other study(ies) available for sapropterin and Autoimmune Diabetes

ArticleYear
GTP cyclohydrolase I prevents diabetic-impaired endothelial progenitor cells and wound healing by suppressing oxidative stress/thrombospondin-1.
    American journal of physiology. Endocrinology and metabolism, 2014, May-15, Volume: 306, Issue:10

    Topics: Animals; Biopterins; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Down-Regulation; Endothelial Cells; GTP Cyclohydrolase; Hematopoietic Stem Cells; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Thrombospondin 1; Wound Healing

2014
Tetrahydrobiopterin rescues impaired responses of cerebral resistance arterioles during type 1 diabetes.
    Diabetes & vascular disease research, 2017, Volume: 14, Issue:1

    Topics: Animals; Arterioles; Biopterins; Cerebral Cortex; Cerebrovascular Circulation; Cerebrovascular Disorders; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Dose-Response Relationship, Drug; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Pia Mater; Rats, Sprague-Dawley; Superoxides; Vascular Resistance; Vasodilation; Vasodilator Agents

2017
High-cholesterol diet augments endothelial dysfunction via elevated oxidative stress and reduced tetrahydrobiopterin in Ins2(Akita) mice, an autosomal dominant mutant type 1 diabetic model.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:8

    Topics: Acetophenones; Animals; Biopterins; Cholesterol, Dietary; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endothelium, Vascular; Enzyme Inhibitors; Genes, Dominant; Insulin; Lipid Peroxides; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; NADPH Oxidases; Oxidative Stress; Protein Precursors; Superoxides; Vasodilation

2009
Diabetes induces changes of catecholamines in primary mesangial cells.
    The international journal of biochemistry & cell biology, 2008, Volume: 40, Issue:4

    Topics: Animals; Biopterins; Catecholamines; Cells, Cultured; Diabetes Mellitus, Type 1; Dopamine; Female; Kidney; Mesangial Cells; Mice; Mice, Inbred NOD; Monoamine Oxidase; Norepinephrine; Tyrosine 3-Monooxygenase

2008
Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus.
    Atherosclerosis, 2008, Volume: 198, Issue:1

    Topics: Animals; Atorvastatin; Biopterins; Body Weight; Cell Adhesion Molecules; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; GTP Cyclohydrolase; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intramolecular Oxidoreductases; Male; Microfilament Proteins; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphoproteins; Pyrroles; Rats; Rats, Wistar; Stem Cells; Tetrahydrofolate Dehydrogenase; Vasodilation

2008