sapropterin has been researched along with Arteriosclerosis in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 17 (94.44) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hirase, T; Hirata, K; Inoue, N; Kawashima, S; Masada, M; Namiki, M; Ozaki, M; Sakurai, H; Yamashita, T; Yasui, H; Yokoyama, M; Yoshida, Y | 1 |
| Tarpey, MM | 1 |
| Duquaine, D; Kalyanaraman, B; Rajagopalan, S; Vásquez-Vivar, J; Whitsett, J | 1 |
| Channon, KM; Guzik, TJ | 1 |
| d'Uscio, LV; Katusic, ZS; Milstien, S; Richardson, D; Smith, L | 1 |
| Alp, NJ; Channon, KM; Choudhury, RP; Khoo, J; McAteer, MA | 1 |
| Kawashima, S; Yokoyama, M | 1 |
| d'Uscio, LV; Katusic, ZS | 1 |
| Kurabayashi, M; Morita, H; Nagai, R; Nakamura, T; Saito, Y | 1 |
| Hirata, Y | 1 |
| Kawashima, S | 1 |
| Cosentino, F; Lüscher, TF | 1 |
| Cooke, JP; Dembinska-Kiec, A; Dulak, J; Florek, I; Guevara, I; Józkowicz, A; Szuba, A; Wójtowicz, A; Zdzienicka, A; Zmudzinska-Grochot, D | 1 |
| Amann, K; Bleeke, T; Kübler, W; Tiefenbacher, CP; Vahl, C; Vogt, A | 1 |
| Jiang, J; Pernow, J; Thorén, P; Tokuno, S; Valen, G | 1 |
| van Hinsbergh, VW | 1 |
| Nomura, T; Ohtsuki, M; Shiraishi, H; Sumi-Ichinose, C | 1 |
| Rabelink, TJ; Stroes, E; Verhaar, MC | 1 |
9 review(s) available for sapropterin and Arteriosclerosis
| Article | Year |
|---|---|
Sepiapterin treatment in atherosclerosis.
Topics: Animals; Arteriosclerosis; Biopterins; Humans; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pteridines; Pterins | 2002 |
Mechanisms of superoxide production in human blood vessels: relationship to endothelial dysfunction, clinical and genetic risk factors.
Topics: Alleles; Arteriosclerosis; Biopterins; Blood Vessels; Endothelium, Vascular; Genetic Predisposition to Disease; Humans; Membrane Transport Proteins; NADPH Dehydrogenase; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphoproteins; Polymorphism, Genetic; Superoxides; Vascular Diseases | 2002 |
Dysfunction of endothelial nitric oxide synthase and atherosclerosis.
Topics: Animals; Antioxidants; Arteriosclerosis; Biopterins; Endothelium, Vascular; Enzyme Induction; Humans; Hypercholesterolemia; Mice; Mice, Knockout; Mice, Transgenic; Models, Animal; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rabbits; Recombinant Fusion Proteins; Risk Factors; Stress, Mechanical; Superoxides | 2004 |
[Involvement of homocysteine in the pathogenesis of hypertension and hypertensive target-organ damage].
Topics: Arginine; Arteriosclerosis; Biopterins; Cell Division; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Hypertension; Insulin Resistance; Muscle, Smooth, Vascular; Nitric Oxide; Oxidative Stress; Risk Factors | 2004 |
[NO and hypertension].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arginine; Arteriosclerosis; Biopterins; C-Reactive Protein; Endothelium, Vascular; Humans; Hypertension; Mutation; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Perindopril; Reactive Oxygen Species; Vasodilation | 2004 |
Malfunction of vascular control in lifestyle-related diseases: endothelial nitric oxide (NO) synthase/NO system in atherosclerosis.
Topics: Animals; Arteriosclerosis; Biopterins; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Superoxides | 2004 |
Tetrahydrobiopterin and endothelial function.
Topics: Animals; Antioxidants; Arteriosclerosis; Biopterins; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Synthase; Reactive Oxygen Species | 1998 |
[Perspectives on tetrahydrobiopterin research].
Topics: Animals; Arteriosclerosis; Biopterins; Central Nervous System Diseases; GTP Cyclohydrolase; Humans; Mice; Mice, Knockout; Phosphorus-Oxygen Lyases | 2001 |
Folates and cardiovascular disease.
Topics: Arteriosclerosis; Biopterins; Cardiovascular Diseases; Endothelium, Vascular; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylenetetrahydrofolate Dehydrogenase (NAD+); Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Oxidoreductases | 2002 |
9 other study(ies) available for sapropterin and Arteriosclerosis
| Article | Year |
|---|---|
Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice.
Topics: Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Biopterins; Cattle; Disease Models, Animal; Female; Gene Expression; Hemodynamics; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III | 2002 |
Altered tetrahydrobiopterin metabolism in atherosclerosis: implications for use of oxidized tetrahydrobiopterin analogues and thiol antioxidants.
Topics: Acetylcholine; Acetylcysteine; Animals; Antioxidants; Aorta, Thoracic; Arteriosclerosis; Biopterins; Calcimycin; Cholesterol; Diet; Endothelium, Vascular; Free Radical Scavengers; Hyperlipidemias; Ionophores; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxygen; Pteridines; Pterins; Rabbits; Sulfhydryl Compounds; Vasodilator Agents | 2002 |
Long-term vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity.
Topics: Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Ascorbic Acid; Biopterins; Cyclic AMP; Cyclic GMP; Dietary Supplements; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; In Vitro Techniques; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Superoxides; Time; Tyrosine; Vasomotor System; Vitamin E | 2003 |
Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.
Topics: Animals; Aorta; Aortic Diseases; Apolipoproteins E; Arteriosclerosis; Biopterins; Coenzymes; Crosses, Genetic; Cyclic GMP; Diet, Atherogenic; Endothelium, Vascular; GTP Cyclohydrolase; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nitric Oxide; Organ Specificity; Receptor, TIE-2; Recombinant Fusion Proteins; Superoxides; Vasodilation | 2004 |
Tetrahydrobiopterin: mediator of endothelial protection.
Topics: Animals; Apolipoproteins E; Arteriosclerosis; Biopterins; Coenzymes; Endothelium, Vascular; Humans; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III | 2004 |
Nitric oxide induces the synthesis of vascular endothelial growth factor by rat vascular smooth muscle cells.
Topics: Animals; Antioxidants; Arteriosclerosis; Biopterins; Cells, Cultured; DNA Primers; Endothelial Growth Factors; Enzyme Inhibitors; Ferrocyanides; Gene Expression Regulation, Enzymologic; Interleukin-1; Lymphokines; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Rats; RNA, Messenger; Thoracic Arteries; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilator Agents | 2000 |
Endothelial dysfunction of coronary resistance arteries is improved by tetrahydrobiopterin in atherosclerosis.
Topics: Acetylcholine; Animals; Arteriosclerosis; Atrial Appendage; Biopterins; Cholesterol; Coronary Vessels; Diet, Atherogenic; Dose-Response Relationship, Drug; Endothelium, Vascular; Histamine; Humans; In Vitro Techniques; Nitroprusside; Pteridines; Pterins; Serotonin; Substance P; Swine, Miniature; Vascular Resistance; Vasoconstriction; Vasodilation; Vasodilator Agents | 2000 |
Endothelial dysfunction in atherosclerotic mice: improved relaxation by combined supplementation with L-arginine-tetrahydrobiopterin and enhanced vasoconstriction by endothelin.
Topics: Acetylcholine; Animals; Arginine; Arteriosclerosis; Biopterins; Dietary Supplements; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Mice; Mice, Inbred C57BL; Nitroprusside; Superoxide Dismutase; Vasoconstriction; Vasodilation | 2000 |
NO or H(2)O(2) for endothelium-dependent vasorelaxation: Tetrahydrobiopterin makes the difference.
Topics: Animals; Arteriosclerosis; Biopterins; Endothelium, Vascular; Humans; Hydrogen Peroxide; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Vasodilation | 2001 |