sapropterin has been researched along with Aortic Diseases in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Al Haj Zen, A; Channon, KM; Chuaiphichai, S; Crabtree, MJ; Douglas, G; Hale, AB; McNeill, E; Patel, J; Rashbrook, VS; Trelfa, L | 1 |
| Alp, NJ; Channon, KM; Cheng, A; Crabtree, MJ; Douglas, G; Hale, AB; Khoo, J; McNeill, E; O'Neill, CA; Schmidt, TS | 1 |
| Alp, NJ; Channon, KM; Choudhury, RP; Khoo, J; McAteer, MA | 1 |
| Croatt, AJ; d'Uscio, LV; Katusic, ZS; Lam, CF; Nath, KA; Peterson, TE; Richardson, DM | 1 |
4 other study(ies) available for sapropterin and Aortic Diseases
| Article | Year |
|---|---|
Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression.
Topics: Animals; Aorta; Aortic Diseases; Atherosclerosis; Biopterins; Blood Pressure; Disease Models, Animal; Disease Progression; Endothelial Cells; Female; Foam Cells; GTP Cyclohydrolase; Macrophages; Male; Mice, Knockout, ApoE; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Plaque, Atherosclerotic; Reactive Oxygen Species; Vascular Cell Adhesion Molecule-1; Vasoconstriction; Vasodilation | 2018 |
Tetrahydrobiopterin supplementation reduces atherosclerosis and vascular inflammation in apolipoprotein E-knockout mice.
Topics: Administration, Oral; Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Biopterins; Chemotaxis, Leukocyte; Disease Progression; Drug Administration Schedule; Drug Evaluation, Preclinical; Endothelium, Vascular; Hemodynamics; Lipids; Male; Mice; Mice, Knockout; RNA, Messenger; Tissue Distribution; Vascular Cell Adhesion Molecule-1 | 2010 |
Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.
Topics: Animals; Aorta; Aortic Diseases; Apolipoproteins E; Arteriosclerosis; Biopterins; Coenzymes; Crosses, Genetic; Cyclic GMP; Diet, Atherogenic; Endothelium, Vascular; GTP Cyclohydrolase; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nitric Oxide; Organ Specificity; Receptor, TIE-2; Recombinant Fusion Proteins; Superoxides; Vasodilation | 2004 |
Increased blood flow causes coordinated upregulation of arterial eNOS and biosynthesis of tetrahydrobiopterin.
Topics: Animals; Aorta; Aortic Diseases; Arteriovenous Fistula; Biopterins; Blotting, Western; Cyclic GMP; GTP Cyclohydrolase; Hemodynamics; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Up-Regulation; Vasomotor System; Vena Cava, Inferior | 2006 |