Page last updated: 2024-08-21

sapropterin and Angiogenesis, Pathologic

sapropterin has been researched along with Angiogenesis, Pathologic in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bosch, J; Fernández-Iglesias, A; Gracia-Sancho, J; Maeso-Díaz, R; Navarro-Zornoza, M1
Barberis, A; Beech, JS; Buffa, F; Cai, S; Chen, L; Harris, AL; Kleibeuker, E; Leek, RD; Roxanis, I; Worth, A; Zeng, X; Zhang, W1
Cui, J; Dai, Y; Gan, P; Li, W1
Abraldes, JG; Bosch, J; Fernández, M; García-Pagán, JC1
Briggs, SS; Cai, S; Chen, L; Harris, AL; Kerr, DJ; Leek, R; Li, J; O'Neill, E; Wang, J; Zeng, X1
Becker, C; Brüne, B; Ferreirós, N; Geisslinger, G; Häussler, A; Labocha, S; Lim, HY; Lötsch, J; Myrczek, T; Pickert, G; Tegeder, I; Waldner, M; Weigert, A1
Cinatl, J; Doerr, HW; Michaelis, M; Michaelis, R; Mohamed, A; Schmidt, H; Suhan, T1
Kelly, KA; Marinos, RS; Meininger, CJ; Wu, G; Zhang, W1

Reviews

2 review(s) available for sapropterin and Angiogenesis, Pathologic

ArticleYear
New cellular and molecular targets for the treatment of portal hypertension.
    Hepatology international, 2015, Volume: 9, Issue:2

    Topics: Acetates; Antioxidants; Biopterins; Chenodeoxycholic Acid; Cyclopropanes; Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Portal; Leukotriene Antagonists; Liver Circulation; Liver Cirrhosis; Microvessels; Molecular Targeted Therapy; Naphthalenes; Neovascularization, Pathologic; Propionates; Quinolines; Sulfides; Vascular Resistance

2015
Hepatic endothelial dysfunction and abnormal angiogenesis: new targets in the treatment of portal hypertension.
    Journal of hepatology, 2010, Volume: 53, Issue:3

    Topics: Antioxidants; Biopterins; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Portal; Liver; Neovascularization, Pathologic; Nitric Oxide; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Signal Transduction; Splanchnic Circulation; Vascular Resistance

2010

Other Studies

6 other study(ies) available for sapropterin and Angiogenesis, Pathologic

ArticleYear
Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth.
    Oncotarget, 2016, Feb-23, Volume: 7, Issue:8

    Topics: 3T3 Cells; Angiopoietin-1; Animals; Biopterins; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enzyme Activation; Epithelial Cells; Female; GTP Cyclohydrolase; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Mice, SCID; Neoplasm Transplantation; Neovascularization, Pathologic; Phosphorylation; Receptor, TIE-2; RNA, Messenger; Stromal Cells; Tissue Array Analysis; Transplantation, Heterologous

2016
Downregulation of tetrahydrobiopterin inhibits tumor angiogenesis in BALB/c-nu mice with hepatocellular carcinoma.
    Oncology reports, 2016, Volume: 36, Issue:2

    Topics: Animals; Biopterins; Carcinoma, Hepatocellular; Cell Line, Tumor; Down-Regulation; Genes, ras; Hep G2 Cells; Humans; Hypoxanthines; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; RNA, Messenger

2016
Roles of tetrahydrobiopterin in promoting tumor angiogenesis.
    The American journal of pathology, 2010, Volume: 177, Issue:5

    Topics: Animals; Biopterins; Cell Movement; Cell Proliferation; Chlorocebus aethiops; COS Cells; Enzyme Activation; Humans; Mice; Neovascularization, Pathologic; NIH 3T3 Cells; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pterins; ras Proteins; Signal Transduction; Tumor Microenvironment

2010
Inhibition of GTP cyclohydrolase attenuates tumor growth by reducing angiogenesis and M2-like polarization of tumor associated macrophages.
    International journal of cancer, 2013, Feb-01, Volume: 132, Issue:3

    Topics: Animals; Biomarkers, Tumor; Biopterins; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chemokines; Colonic Neoplasms; Enzyme Inhibitors; Female; GTP Cyclohydrolase; HT29 Cells; Human Umbilical Vein Endothelial Cells; Humans; Macrophages; Male; Melanoma; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Neoplasms; Neopterin; Neovascularization, Pathologic; Nitric Oxide Synthase Type III; RNA Interference; RNA, Small Interfering; Skin Neoplasms; Transplantation, Heterologous

2013
Ribavirin inhibits angiogenesis by tetrahydrobiopterin depletion.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2007, Volume: 21, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Biopterins; Cell Proliferation; Cells, Cultured; Chickens; Chromatography, High Pressure Liquid; Cyclic GMP; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Humans; Neovascularization, Pathologic; Nitric Oxide; Nitric Oxide Synthase Type III; Radioimmunoassay; Ribavirin

2007
Tetrahydrobiopterin levels regulate endothelial cell proliferation.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:2

    Topics: Animals; Biopterins; Cell Division; Cells, Cultured; Diabetes Mellitus, Experimental; Endothelium, Vascular; Neovascularization, Pathologic; Nitric Oxide; Rats

2001