sapropterin has been researched along with Angiogenesis, Pathologic in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bosch, J; Fernández-Iglesias, A; Gracia-Sancho, J; Maeso-Díaz, R; Navarro-Zornoza, M | 1 |
| Barberis, A; Beech, JS; Buffa, F; Cai, S; Chen, L; Harris, AL; Kleibeuker, E; Leek, RD; Roxanis, I; Worth, A; Zeng, X; Zhang, W | 1 |
| Cui, J; Dai, Y; Gan, P; Li, W | 1 |
| Abraldes, JG; Bosch, J; Fernández, M; García-Pagán, JC | 1 |
| Briggs, SS; Cai, S; Chen, L; Harris, AL; Kerr, DJ; Leek, R; Li, J; O'Neill, E; Wang, J; Zeng, X | 1 |
| Becker, C; Brüne, B; Ferreirós, N; Geisslinger, G; Häussler, A; Labocha, S; Lim, HY; Lötsch, J; Myrczek, T; Pickert, G; Tegeder, I; Waldner, M; Weigert, A | 1 |
| Cinatl, J; Doerr, HW; Michaelis, M; Michaelis, R; Mohamed, A; Schmidt, H; Suhan, T | 1 |
| Kelly, KA; Marinos, RS; Meininger, CJ; Wu, G; Zhang, W | 1 |
2 review(s) available for sapropterin and Angiogenesis, Pathologic
| Article | Year |
|---|---|
New cellular and molecular targets for the treatment of portal hypertension.
Topics: Acetates; Antioxidants; Biopterins; Chenodeoxycholic Acid; Cyclopropanes; Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Portal; Leukotriene Antagonists; Liver Circulation; Liver Cirrhosis; Microvessels; Molecular Targeted Therapy; Naphthalenes; Neovascularization, Pathologic; Propionates; Quinolines; Sulfides; Vascular Resistance | 2015 |
Hepatic endothelial dysfunction and abnormal angiogenesis: new targets in the treatment of portal hypertension.
Topics: Antioxidants; Biopterins; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Portal; Liver; Neovascularization, Pathologic; Nitric Oxide; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Signal Transduction; Splanchnic Circulation; Vascular Resistance | 2010 |
6 other study(ies) available for sapropterin and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth.
Topics: 3T3 Cells; Angiopoietin-1; Animals; Biopterins; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enzyme Activation; Epithelial Cells; Female; GTP Cyclohydrolase; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Mice, SCID; Neoplasm Transplantation; Neovascularization, Pathologic; Phosphorylation; Receptor, TIE-2; RNA, Messenger; Stromal Cells; Tissue Array Analysis; Transplantation, Heterologous | 2016 |
Downregulation of tetrahydrobiopterin inhibits tumor angiogenesis in BALB/c-nu mice with hepatocellular carcinoma.
Topics: Animals; Biopterins; Carcinoma, Hepatocellular; Cell Line, Tumor; Down-Regulation; Genes, ras; Hep G2 Cells; Humans; Hypoxanthines; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; RNA, Messenger | 2016 |
Roles of tetrahydrobiopterin in promoting tumor angiogenesis.
Topics: Animals; Biopterins; Cell Movement; Cell Proliferation; Chlorocebus aethiops; COS Cells; Enzyme Activation; Humans; Mice; Neovascularization, Pathologic; NIH 3T3 Cells; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pterins; ras Proteins; Signal Transduction; Tumor Microenvironment | 2010 |
Inhibition of GTP cyclohydrolase attenuates tumor growth by reducing angiogenesis and M2-like polarization of tumor associated macrophages.
Topics: Animals; Biomarkers, Tumor; Biopterins; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chemokines; Colonic Neoplasms; Enzyme Inhibitors; Female; GTP Cyclohydrolase; HT29 Cells; Human Umbilical Vein Endothelial Cells; Humans; Macrophages; Male; Melanoma; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Neoplasms; Neopterin; Neovascularization, Pathologic; Nitric Oxide Synthase Type III; RNA Interference; RNA, Small Interfering; Skin Neoplasms; Transplantation, Heterologous | 2013 |
Ribavirin inhibits angiogenesis by tetrahydrobiopterin depletion.
Topics: Angiogenesis Inhibitors; Animals; Biopterins; Cell Proliferation; Cells, Cultured; Chickens; Chromatography, High Pressure Liquid; Cyclic GMP; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Humans; Neovascularization, Pathologic; Nitric Oxide; Nitric Oxide Synthase Type III; Radioimmunoassay; Ribavirin | 2007 |
Tetrahydrobiopterin levels regulate endothelial cell proliferation.
Topics: Animals; Biopterins; Cell Division; Cells, Cultured; Diabetes Mellitus, Experimental; Endothelium, Vascular; Neovascularization, Pathologic; Nitric Oxide; Rats | 2001 |