sanguinarine has been researched along with Necrosis in 8 studies
benzophenanthridine alkaloid : A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sanguinarine treatment resulted in a reduction of cell migration, in a dose-dependent inhibition of cell viability and in the induction of cell death by apoptosis in both human (MDA-MB-231 cells) and mouse (A17 cells) in vitro models of BLBC." | 5.40 | Sanguinarine suppresses basal-like breast cancer growth through dihydrofolate reductase inhibition. ( Amici, A; Andreani, C; Bartolacci, C; Belletti, B; Gambini, V; Garulli, C; Giangrossi, M; Iezzi, M; Kalogris, C; Lucci, C; Marchini, C; Pietrella, L; Pucciarelli, S; Tilio, M; Zabaleta, ME, 2014) |
| "Sanguinarine is a benzopheanthridine alkaloid present in the root of Sanguinaria canadensis L." | 5.34 | Induction of necrosis and apoptosis to KB cancer cells by sanguinarine is associated with reactive oxygen species production and mitochondrial membrane depolarization. ( Chan, CP; Chang, MC; Chen, LI; Jeng, JH; Lee, PH; Lin, BR; Tsai, YL; Wang, YJ; Wang, YL, 2007) |
| " The vinblastin-resistant, Pgp positive CEM-VLB 1000 and its wild type (Pgp-negative and vinblastin-sensitive) counterpart CEM-T4 human leukemia cells, when treated with the alkaloid sanguinarine, were both found to undergo apoptosis at concentrations of 1." | 3.73 | Sanguinarine overcomes P-glycoprotein-mediated multidrug-resistance via induction of apoptosis and oncosis in CEM-VLB 1000 cells. ( Hallock, S; Liepins, A; Tang, SC; Trump, B; Weerasinghe, P, 2006) |
| "Sanguinarine treatment resulted in a reduction of cell migration, in a dose-dependent inhibition of cell viability and in the induction of cell death by apoptosis in both human (MDA-MB-231 cells) and mouse (A17 cells) in vitro models of BLBC." | 1.40 | Sanguinarine suppresses basal-like breast cancer growth through dihydrofolate reductase inhibition. ( Amici, A; Andreani, C; Bartolacci, C; Belletti, B; Gambini, V; Garulli, C; Giangrossi, M; Iezzi, M; Kalogris, C; Lucci, C; Marchini, C; Pietrella, L; Pucciarelli, S; Tilio, M; Zabaleta, ME, 2014) |
| "Sanguinarine is a benzopheanthridine alkaloid present in the root of Sanguinaria canadensis L." | 1.34 | Induction of necrosis and apoptosis to KB cancer cells by sanguinarine is associated with reactive oxygen species production and mitochondrial membrane depolarization. ( Chan, CP; Chang, MC; Chen, LI; Jeng, JH; Lee, PH; Lin, BR; Tsai, YL; Wang, YJ; Wang, YL, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ong, NC | 1 |
| Sham, E | 1 |
| Adams, BM | 1 |
| Kalogris, C | 1 |
| Garulli, C | 1 |
| Pietrella, L | 1 |
| Gambini, V | 1 |
| Pucciarelli, S | 1 |
| Lucci, C | 1 |
| Tilio, M | 1 |
| Zabaleta, ME | 1 |
| Bartolacci, C | 1 |
| Andreani, C | 1 |
| Giangrossi, M | 1 |
| Iezzi, M | 1 |
| Belletti, B | 1 |
| Marchini, C | 1 |
| Amici, A | 1 |
| Mishra, V | 1 |
| Saxena, DK | 1 |
| Das, M | 1 |
| Weerasinghe, P | 2 |
| Buja, LM | 1 |
| Kemény-Beke, A | 1 |
| Aradi, J | 1 |
| Damjanovich, J | 1 |
| Beck, Z | 1 |
| Facskó, A | 1 |
| Berta, A | 1 |
| Bodnár, A | 1 |
| Hallock, S | 1 |
| Tang, SC | 1 |
| Trump, B | 1 |
| Liepins, A | 1 |
| Chang, MC | 1 |
| Chan, CP | 1 |
| Wang, YJ | 1 |
| Lee, PH | 1 |
| Chen, LI | 1 |
| Tsai, YL | 1 |
| Lin, BR | 1 |
| Wang, YL | 1 |
| Jeng, JH | 1 |
| Moran, AM | 1 |
| Helm, KF | 1 |
1 review available for sanguinarine and Necrosis
| Article | Year |
|---|---|
Oncosis: an important non-apoptotic mode of cell death.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Cell Death; Cell Enlargement; Human | 2012 |
7 other studies available for sanguinarine and Necrosis
| Article | Year |
|---|---|
Use of unlicensed black salve for cutaneous malignancy.
Topics: Antineoplastic Agents; Australia; Benzophenanthridines; Chlorides; Drug Approval; Humans; Isoquinoli | 2014 |
Sanguinarine suppresses basal-like breast cancer growth through dihydrofolate reductase inhibition.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzophenanthridines; Breast Neoplasms; Cell | 2014 |
Effect of argemone oil and argemone alkaloid, sanguinarine on Sertoli-germ cell coculture.
Topics: Alkaloids; Animals; Apoptosis; Argemone; Benzophenanthridines; Cell Proliferation; Cell Survival; Co | 2009 |
Apoptotic response of uveal melanoma cells upon treatment with chelidonine, sanguinarine and chelerythrine.
Topics: Alkaloids; Annexin A5; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Berberine Alkaloids; | 2006 |
Sanguinarine overcomes P-glycoprotein-mediated multidrug-resistance via induction of apoptosis and oncosis in CEM-VLB 1000 cells.
Topics: Alkaloids; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-2-Associated X Pr | 2006 |
Induction of necrosis and apoptosis to KB cancer cells by sanguinarine is associated with reactive oxygen species production and mitochondrial membrane depolarization.
Topics: Acetylcysteine; Alkaloids; Annexin A5; Anticarcinogenic Agents; Antioxidants; Apoptosis; Benzophenan | 2007 |
Histopathologic findings and diagnostic difficulties posed with use of escharotic agents for treatment of skin lesions: a case report and review of the literature.
Topics: Adult; Alkaloids; Antineoplastic Agents; Benzophenanthridines; Biomarkers, Tumor; Complementary Ther | 2008 |