sanguinarine has been researched along with Lung Neoplasms in 13 studies
benzophenanthridine alkaloid : A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A large number of breast cancer patients perishes due to metastasis instead of primary tumor, but molecular mechanisms contributing towards cancer metastasis remain poorly understood." | 5.62 | Sanguinarine impedes metastasis and causes inversion of epithelial to mesenchymal transition in breast cancer. ( Ghauri, MA; Sarwar, A; Su, Q; Ullah, A; Wang, J; Wu, Q; Zhang, D; Zhang, Y, 2021) |
| "The human pancreatic carcinoid cell line, BON-1, human typical bronchial carcinoid cell line NCI-H727 and the human atypical bronchial carcinoid cell line NCI-H720 were tested." | 5.36 | The cytotoxic agents NSC-95397, brefeldin A, bortezomib and sanguinarine induce apoptosis in neuroendocrine tumors in vitro. ( Granberg, D; Hassan, S; Larsson, DE; Oberg, K; Wickström, M, 2010) |
| "Lung carcinoma is the chief cause of malignancy-related mortality in China." | 1.72 | Sanguinarine Represses the Growth and Metastasis of Non-small Cell Lung Cancer by Facilitating Ferroptosis. ( Fang, Z; Li, Y; Luo, Y; Teng, W; Tian, J; Wang, Y; Wu, J; Xu, R; Zhang, B, 2022) |
| "Effective treatment of lung cancer remains a significant clinical challenge due to its multidrug resistance and side effects of the current treatment options." | 1.62 | Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway. ( Bhat, AA; Chawdhery, MZ; Dermime, S; Haris, M; Jochebeth, A; Khan, AQ; Kulinski, M; Kuttikrishnan, S; Prabhu, KS; Raheed, T; Raza, SS; Siveen, KS; Steinhoff, M; Uddin, S, 2021) |
| "A large number of breast cancer patients perishes due to metastasis instead of primary tumor, but molecular mechanisms contributing towards cancer metastasis remain poorly understood." | 1.62 | Sanguinarine impedes metastasis and causes inversion of epithelial to mesenchymal transition in breast cancer. ( Ghauri, MA; Sarwar, A; Su, Q; Ullah, A; Wang, J; Wu, Q; Zhang, D; Zhang, Y, 2021) |
| "Sanguinarine (SNG) is a benzophenanthridine alkaloid isolated from plants of the Papaveraceae family that possess diverse biological activities." | 1.46 | Sanguinarine exhibits antitumor activity via up-regulation of Fas-associated factor 1 in non-small cell lung cancer. ( Peng, T; Sun, Z; Wang, Z; Wei, G; Xu, Y; Yan, J, 2017) |
| "Lung cancer is a neoplasm with a 5-year survival rate of less than 15 % and a leading cause of death worldwide, despite recent progress in treatment and diagnostic methods." | 1.43 | Construction and application of a lung cancer stem cell model: antitumor drug screening and molecular mechanism of the inhibitory effects of sanguinarine. ( Fang, Y; Fang, Z; Li, Y; Wu, J; Yang, J; Yin, X; Zhao, F; Zhu, S, 2016) |
| "The human pancreatic carcinoid cell line, BON-1, human typical bronchial carcinoid cell line NCI-H727 and the human atypical bronchial carcinoid cell line NCI-H720 were tested." | 1.36 | The cytotoxic agents NSC-95397, brefeldin A, bortezomib and sanguinarine induce apoptosis in neuroendocrine tumors in vitro. ( Granberg, D; Hassan, S; Larsson, DE; Oberg, K; Wickström, M, 2010) |
| "Treatment with sanguinarine led to activation of caspases and MAPKs as well as increased MKP-1 expression." | 1.35 | Sanguinarine induces apoptosis in A549 human lung cancer cells primarily via cellular glutathione depletion. ( Baek, WK; Jang, BC; Jung, KH; Lee, TY; Park, GY; Park, JG; Song, DK; Suh, SI; Yoo, SK, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 5 (38.46) | 2.80 |
| Authors | Studies |
|---|---|
| Bodle, CR | 1 |
| Mackie, DI | 1 |
| Hayes, MP | 1 |
| Schamp, JH | 1 |
| Miller, MR | 1 |
| Henry, MD | 1 |
| Doorn, JA | 1 |
| Houtman, JCD | 1 |
| James, MA | 1 |
| Roman, DL | 1 |
| Prabhu, KS | 1 |
| Bhat, AA | 1 |
| Siveen, KS | 1 |
| Kuttikrishnan, S | 1 |
| Raza, SS | 1 |
| Raheed, T | 1 |
| Jochebeth, A | 1 |
| Khan, AQ | 1 |
| Chawdhery, MZ | 1 |
| Haris, M | 1 |
| Kulinski, M | 1 |
| Dermime, S | 1 |
| Steinhoff, M | 1 |
| Uddin, S | 1 |
| Xu, R | 1 |
| Wu, J | 3 |
| Luo, Y | 2 |
| Wang, Y | 1 |
| Tian, J | 1 |
| Teng, W | 1 |
| Zhang, B | 1 |
| Fang, Z | 3 |
| Li, Y | 3 |
| Li, B | 1 |
| Zhou, Y | 1 |
| Hałas-Wiśniewska, M | 1 |
| Zielińska, W | 1 |
| Izdebska, M | 1 |
| Grzanka, A | 1 |
| Ghauri, MA | 1 |
| Su, Q | 1 |
| Ullah, A | 1 |
| Wang, J | 1 |
| Sarwar, A | 1 |
| Wu, Q | 1 |
| Zhang, D | 1 |
| Zhang, Y | 2 |
| Gatti, L | 1 |
| Cossa, G | 1 |
| Tinelli, S | 1 |
| Carenini, N | 1 |
| Arrighetti, N | 1 |
| Pennati, M | 1 |
| Cominetti, D | 1 |
| De Cesare, M | 1 |
| Zunino, F | 1 |
| Zaffaroni, N | 1 |
| Perego, P | 1 |
| Gu, S | 1 |
| Yang, XC | 1 |
| Xiang, XY | 1 |
| Wu, Y | 1 |
| Yan, XY | 1 |
| Xue, YN | 1 |
| Sun, LK | 1 |
| Shao, GG | 1 |
| Leung, EL | 1 |
| Fan, XX | 1 |
| Wong, MP | 1 |
| Jiang, ZH | 1 |
| Liu, ZQ | 1 |
| Yao, XJ | 1 |
| Lu, LL | 1 |
| Zhou, YL | 1 |
| Yau, LF | 1 |
| Tin, VP | 1 |
| Liu, L | 1 |
| Yang, J | 1 |
| Yin, X | 1 |
| Fang, Y | 1 |
| Zhao, F | 1 |
| Zhu, S | 1 |
| Wei, G | 1 |
| Xu, Y | 1 |
| Peng, T | 1 |
| Yan, J | 1 |
| Wang, Z | 1 |
| Sun, Z | 1 |
| Jang, BC | 1 |
| Park, JG | 1 |
| Song, DK | 1 |
| Baek, WK | 1 |
| Yoo, SK | 1 |
| Jung, KH | 1 |
| Park, GY | 1 |
| Lee, TY | 1 |
| Suh, SI | 1 |
| Larsson, DE | 1 |
| Wickström, M | 1 |
| Hassan, S | 1 |
| Oberg, K | 1 |
| Granberg, D | 1 |
13 other studies available for sanguinarine and Lung Neoplasms
| Article | Year |
|---|---|
Natural Products Discovered in a High-Throughput Screen Identified as Inhibitors of RGS17 and as Cytostatic and Cytotoxic Agents for Lung and Prostate Cancer Cell Lines.
Topics: Benzophenanthridines; Biological Products; Cytostatic Agents; Cytotoxins; GTP-Binding Protein Regula | 2017 |
Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzophenanthridines; Carcinoma, Non-Small-Ce | 2021 |
Sanguinarine Represses the Growth and Metastasis of Non-small Cell Lung Cancer by Facilitating Ferroptosis.
Topics: Benzophenanthridines; Carcinoma; Carcinoma, Non-Small-Cell Lung; Ferroptosis; Glutathione; Humans; I | 2022 |
Role of sanguinarine in regulating immunosuppression in a Lewis lung cancer mouse model.
Topics: Animals; Benzophenanthridines; Carcinoma, Lewis Lung; Disease Models, Animal; Immunosuppression Ther | 2022 |
The Synergistic Effect of Piperlongumine and Sanguinarine on the Non-Small Lung Cancer.
Topics: Anti-Infective Agents; Apoptosis; Benzophenanthridines; Carcinoma, Non-Small-Cell Lung; Cell Cycle; | 2020 |
Sanguinarine impedes metastasis and causes inversion of epithelial to mesenchymal transition in breast cancer.
Topics: Animals; Benzophenanthridines; Breast Neoplasms; Cell Line, Tumor; Epithelial-Mesenchymal Transition | 2021 |
Improved apoptotic cell death in drug-resistant non-small-cell lung cancer cells by tumor necrosis factor-related apoptosis-inducing ligand-based treatment.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Benzophenanthridines; Carcinoma, Non | 2014 |
Sanguinarine-induced apoptosis in lung adenocarcinoma cells is dependent on reactive oxygen species production and endoplasmic reticulum stress.
Topics: Acetylcysteine; Adenocarcinoma; Adenocarcinoma of Lung; Apoptosis; Benzophenanthridines; Cell Line, | 2015 |
Targeting Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer by Inducing Epidermal Growth Factor Receptor Degradation via Methionine 790 Oxidation.
Topics: Animals; Apoptosis; Benzophenanthridines; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease | 2016 |
Construction and application of a lung cancer stem cell model: antitumor drug screening and molecular mechanism of the inhibitory effects of sanguinarine.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Biomarkers, Tumor; Blotting, Wester | 2016 |
Sanguinarine exhibits antitumor activity via up-regulation of Fas-associated factor 1 in non-small cell lung cancer.
Topics: A549 Cells; Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Apoptos | 2017 |
Sanguinarine induces apoptosis in A549 human lung cancer cells primarily via cellular glutathione depletion.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Benzophenanthridines; | 2009 |
The cytotoxic agents NSC-95397, brefeldin A, bortezomib and sanguinarine induce apoptosis in neuroendocrine tumors in vitro.
Topics: Apoptosis; Benzophenanthridines; Boronic Acids; Bortezomib; Brefeldin A; Carcinoid Tumor; Carcinoma, | 2010 |