sanguinarine has been researched along with Leucocythaemia in 5 studies
benzophenanthridine alkaloid : A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The vinblastin-resistant, Pgp positive CEM-VLB 1000 and its wild type (Pgp-negative and vinblastin-sensitive) counterpart CEM-T4 human leukemia cells, when treated with the alkaloid sanguinarine, were both found to undergo apoptosis at concentrations of 1." | 3.73 | Sanguinarine overcomes P-glycoprotein-mediated multidrug-resistance via induction of apoptosis and oncosis in CEM-VLB 1000 cells. ( Hallock, S; Liepins, A; Tang, SC; Trump, B; Weerasinghe, P, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eid, SY | 1 |
| El-Readi, MZ | 1 |
| Eldin, EE | 1 |
| Fatani, SH | 1 |
| Wink, M | 1 |
| Rahman, A | 1 |
| Thayyullathil, F | 1 |
| Pallichankandy, S | 1 |
| Galadari, S | 1 |
| Weerasinghe, P | 2 |
| Buja, LM | 1 |
| Hallock, S | 1 |
| Tang, SC | 1 |
| Trump, B | 1 |
| Liepins, A | 1 |
| Kaminskyy, V | 1 |
| Lin, KW | 1 |
| Filyak, Y | 1 |
| Stoika, R | 1 |
1 review available for sanguinarine and Leucocythaemia
| Article | Year |
|---|---|
Oncosis: an important non-apoptotic mode of cell death.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Cell Death; Cell Enlargement; Human | 2012 |
4 other studies available for sanguinarine and Leucocythaemia
| Article | Year |
|---|---|
Influence of combinations of digitonin with selected phenolics, terpenoids, and alkaloids on the expression and activity of P-glycoprotein in leukaemia and colon cancer cells.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member | 2013 |
Hydrogen peroxide/ceramide/Akt signaling axis play a critical role in the antileukemic potential of sanguinarine.
Topics: Apoptosis; Benzophenanthridines; Cell Line, Tumor; Ceramides; DNA Fragmentation; Gene Expression Reg | 2016 |
Sanguinarine overcomes P-glycoprotein-mediated multidrug-resistance via induction of apoptosis and oncosis in CEM-VLB 1000 cells.
Topics: Alkaloids; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-2-Associated X Pr | 2006 |
Differential effect of sanguinarine, chelerythrine and chelidonine on DNA damage and cell viability in primary mouse spleen cells and mouse leukemic cells.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Benzophenanthridines; Cell Line, Tumor; Cell | 2008 |