sanguinarine has been researched along with Glioma in 2 studies
benzophenanthridine alkaloid : A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malignant gliomas are notoriously resistant to therapies that induce apoptosis, but are less resistant to therapies that induce autophagy." | 5.42 | ROS-dependent activation of autophagy is a critical mechanism for the induction of anti-glioma effect of sanguinarine. ( Galadari, S; Pallichankandy, S; Rahman, A; Thayyullathil, F, 2015) |
| "Quaternary benzo[c]phenanthridine alkaloids (QBA), fagaronine (FA), sanguinarine (SA), chelerythrine (CHE) and the QBA extract from Macleya cordata (EX) exerted differential inhibitory effect on the hydrolytic activity of particular dipeptidyl peptidase (DPP)-like enzyme isolated from human blood plasma and from human and rat glioma cell lines." | 3.72 | Quaternary benzo[c]phenanthridine alkaloids as inhibitors of dipeptidyl peptidase IV-like activity baring enzymes in human blood plasma and glioma cell lines. ( Malík, R; Sedo, A; Simánek, V; Ulrichová, J; Vicar, J, 2003) |
| "Malignant gliomas are notoriously resistant to therapies that induce apoptosis, but are less resistant to therapies that induce autophagy." | 1.42 | ROS-dependent activation of autophagy is a critical mechanism for the induction of anti-glioma effect of sanguinarine. ( Galadari, S; Pallichankandy, S; Rahman, A; Thayyullathil, F, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pallichankandy, S | 1 |
| Rahman, A | 1 |
| Thayyullathil, F | 1 |
| Galadari, S | 1 |
| Sedo, A | 1 |
| Malík, R | 1 |
| Vicar, J | 1 |
| Simánek, V | 1 |
| Ulrichová, J | 1 |
2 other studies available for sanguinarine and Glioma
| Article | Year |
|---|---|
ROS-dependent activation of autophagy is a critical mechanism for the induction of anti-glioma effect of sanguinarine.
Topics: Antineoplastic Agents; Autophagy; Benzophenanthridines; Blotting, Western; Brain Neoplasms; Cell Lin | 2015 |
Quaternary benzo[c]phenanthridine alkaloids as inhibitors of dipeptidyl peptidase IV-like activity baring enzymes in human blood plasma and glioma cell lines.
Topics: Alkaloids; Animals; Benzophenanthridines; Cell Line, Tumor; Chromatography, Gel; Dipeptidyl Peptidas | 2003 |