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sanguinarine and Disease Models, Animal

sanguinarine has been researched along with Disease Models, Animal in 15 studies

benzophenanthridine alkaloid : A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Sanguinarine (SG) is a natural plant medicine with anti-inflammatory and neuroprotection effects."5.56Sanguinarine Attenuates Neuropathic Pain by Inhibiting P38 MAPK Activated Neuroinflammation in Rat Model. ( Li, P; Liang, LS; Wang, YX; Yu, C; Zhang, KG; Zheng, ZC, 2020)
" Ethanol-induced gastric ulcer model was performed on Kunming mice to examine the anti-inflammatory activity of SG-SLNs and compare it with sanguinarine (SG)."3.85Preparation, Characterization and Anti-Ulcer Efficacy of Sanguinarine Loaded Solid Lipid Nanoparticles. ( Li, H; Li, W; Niu, X; Sun, Q; Wang, X; Wang, Y, 2017)
"We investigated the antidepressant effects of bilateral intra-the ventrolateral orbital cortex (VLO) administration of sanguinarine (SA), a selective mitogen-activated protein kinase phosphatase-1 (Mkp-1) inhibitor, in rats that had been subjected to a forced swimming test (FST) which is a classic animal model of depression."3.78Microinjection of sanguinarine into the ventrolateral orbital cortex inhibits Mkp-1 and exerts an antidepressant-like effect in rats. ( Chen, Y; Peng, Z; Sun, R; Tan, Q; Wang, H; Zhang, R, 2012)
"The ergosterol pathway is a prime antifungal target as it is required for fungal survival, yet is not involved in human homeostasis."1.62Plant-derived isoquinoline alkaloids that target ergosterol biosynthesis discovered by using a novel antifungal screening tool. ( Deyrup, ST; He, ZD; Liu, XB; Ng, TW; Qing, ZX; Song, X; Wong-Deyrup, SW; Zeng, JG; Zhang, HJ, 2021)
"Sanguinarine is a natural plant medicine with anti-inflammatory effects, but its effect on neuropathic pain remains unclear."1.62Sanguinarine Attenuates Neuropathic Pain in a Rat Model of Chronic Constriction Injury. ( Li, P; Wang, YX; Yang, G; Yu, C; Zheng, ZC, 2021)
"Sanguinarine is a benzophenanthridine alkaloid that has biological activity, such as antibacterial, antitumour and antiparasitic activities."1.56Sanguinarine has anthelmintic activity against the enteral and parenteral phases of trichinella infection in experimentally infected mice. ( Huang, H; Jiang, Y; Kang, Y; Liu, K; Shi, C; Wang, C; Wang, D; Wang, G; Wang, J; Yang, G; Yang, W; Yao, J, 2020)
"Sanguinarine (SG) is a natural plant medicine with anti-inflammatory and neuroprotection effects."1.56Sanguinarine Attenuates Neuropathic Pain by Inhibiting P38 MAPK Activated Neuroinflammation in Rat Model. ( Li, P; Liang, LS; Wang, YX; Yu, C; Zhang, KG; Zheng, ZC, 2020)
"Sanguinarine treatment (0."1.48Anti-osteoporosis activity of Sanguinarine in preosteoblast MC3T3-E1 cells and an ovariectomized rat model. ( Wang, G; Xie, J; Yang, H; Zhang, F; Zhang, G, 2018)
"The sanguinarine (SG) was studied for its pharmacokinetic and anti-inflammatory activities with prepared solid lipid nanoparticles (SLNs)."1.40Pharmacokinetic and anti-inflammatory effects of sanguinarine solid lipid nanoparticles. ( Hu, H; Li, H; Li, W; Li, Y; Mu, Q; Niu, X; Yao, H; Zhao, G, 2014)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (60.00)24.3611
2020's6 (40.00)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W3
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Li, B1
Luo, Y1
Zhou, Y1
Wu, J1
Fang, Z1
Li, Y2
Huang, H1
Yao, J1
Liu, K1
Yang, W1
Wang, G2
Shi, C1
Jiang, Y1
Wang, J1
Kang, Y1
Wang, D1
Wang, C1
Yang, G2
Yu, C2
Li, P2
Wang, YX2
Zhang, KG1
Zheng, ZC2
Liang, LS1
Wong-Deyrup, SW1
Song, X1
Ng, TW1
Liu, XB1
Zeng, JG1
Qing, ZX1
Deyrup, ST1
He, ZD1
Zhang, HJ1
Sun, Q1
Li, H2
Wang, X1
Wang, Y1
Niu, X2
Ma, Y1
Chu, J1
Ma, J1
Ning, L1
Zhou, K1
Fang, X1
Zhang, F1
Xie, J1
Zhang, G1
Yang, H1
Kikuchi, N1
Satoh, K1
Kurosawa, R1
Yaoita, N1
Elias-Al-Mamun, M1
Siddique, MAH1
Omura, J1
Satoh, T1
Nogi, M1
Sunamura, S1
Miyata, S1
Saito, Y1
Hoshikawa, Y1
Okada, Y1
Shimokawa, H1
Yao, H1
Mu, Q1
Zhao, G1
Hu, H1
Leung, EL1
Fan, XX1
Wong, MP1
Jiang, ZH1
Liu, ZQ1
Yao, XJ1
Lu, LL1
Zhou, YL1
Yau, LF1
Tin, VP1
Liu, L1
Ansari, KM1
Das, M1
Chen, Y1
Wang, H2
Zhang, R1
Peng, Z1
Sun, R1
Tan, Q1

Other Studies

15 other studies available for sanguinarine and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Role of sanguinarine in regulating immunosuppression in a Lewis lung cancer mouse model.
    International immunopharmacology, 2022, Volume: 110

    Topics: Animals; Benzophenanthridines; Carcinoma, Lewis Lung; Disease Models, Animal; Immunosuppression Ther

2022
Sanguinarine has anthelmintic activity against the enteral and parenteral phases of trichinella infection in experimentally infected mice.
    Acta tropica, 2020, Volume: 201

    Topics: Animals; Anthelmintics; Benzophenanthridines; Disease Models, Animal; Intestine, Small; Isoquinoline

2020
Sanguinarine Attenuates Neuropathic Pain by Inhibiting P38 MAPK Activated Neuroinflammation in Rat Model.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Animals; Anti-Inflammatory Agents; Benzophenanthridines; Constriction; Disease Models, Animal; Dose-

2020
Plant-derived isoquinoline alkaloids that target ergosterol biosynthesis discovered by using a novel antifungal screening tool.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 137

    Topics: Alkaloids; Animals; Antifungal Agents; Arthrodermataceae; Benzophenanthridines; Disease Models, Anim

2021
Sanguinarine Attenuates Neuropathic Pain in a Rat Model of Chronic Constriction Injury.
    BioMed research international, 2021, Volume: 2021

    Topics: Animals; Benzophenanthridines; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug;

2021
Preparation, Characterization and Anti-Ulcer Efficacy of Sanguinarine Loaded Solid Lipid Nanoparticles.
    Pharmacology, 2017, Volume: 100, Issue:1-2

    Topics: Animals; Anti-Ulcer Agents; Benzophenanthridines; Chemistry, Pharmaceutical; Disease Models, Animal;

2017
Sanguinarine protects against ovariectomy‑induced osteoporosis in mice.
    Molecular medicine reports, 2017, Volume: 16, Issue:1

    Topics: Animals; Benzophenanthridines; Bone and Bones; Bone Remodeling; Disease Models, Animal; Female; Isoq

2017
Anti-osteoporosis activity of Sanguinarine in preosteoblast MC3T3-E1 cells and an ovariectomized rat model.
    Journal of cellular physiology, 2018, Volume: 233, Issue:6

    Topics: 3T3 Cells; AMP-Activated Protein Kinases; Animals; Benzophenanthridines; Bone Density; Bone Density

2018
Selenoprotein P Promotes the Development of Pulmonary Arterial Hypertension: Possible Novel Therapeutic Target.
    Circulation, 2018, 08-07, Volume: 138, Issue:6

    Topics: Animals; Antihypertensive Agents; Apoptosis; Arterial Pressure; Benzophenanthridines; Cell Prolifera

2018
Pharmacokinetic and anti-inflammatory effects of sanguinarine solid lipid nanoparticles.
    Inflammation, 2014, Volume: 37, Issue:2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Benzophenanthridines; Biological Availabili

2014
Targeting Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer by Inducing Epidermal Growth Factor Receptor Degradation via Methionine 790 Oxidation.
    Antioxidants & redox signaling, 2016, Feb-10, Volume: 24, Issue:5

    Topics: Animals; Apoptosis; Benzophenanthridines; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease

2016
Potentiation of tumour promotion by topical application of argemone oil/isolated sanguinarine alkaloid in a model of mouse skin carcinogenesis.
    Chemico-biological interactions, 2010, Dec-05, Volume: 188, Issue:3

    Topics: Administration, Cutaneous; Animals; Benzophenanthridines; Disease Models, Animal; Female; Humans; Is

2010
Microinjection of sanguinarine into the ventrolateral orbital cortex inhibits Mkp-1 and exerts an antidepressant-like effect in rats.
    Neuroscience letters, 2012, Jan-11, Volume: 506, Issue:2

    Topics: Animals; Antidepressive Agents; Benzophenanthridines; Blotting, Western; Cerebral Cortex; Depression

2012