Page last updated: 2024-11-04

sanguinarine and Colorectal Cancer

sanguinarine has been researched along with Colorectal Cancer in 3 studies

benzophenanthridine alkaloid : A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.

Research Excerpts

ExcerptRelevanceReference
"We examined the effects of sanguinarine, a benzophenanthridine alkaloid, on reactive oxygen species (ROS) production and the association of these effects with apoptotic cell death in a human colorectal cancer HCT-116 cell line."7.79Sanguinarine induces apoptosis in human colorectal cancer HCT-116 cells through ROS-mediated Egr-1 activation and mitochondrial dysfunction. ( Choi, YH; Han, MH; Kim, GY; Yoo, YH, 2013)
"To evaluate the in-vivo preclinical antitumor activity of sanguinarine in a rat syngeneic model of colorectal cancer."7.78Antitumor effects of the benzophenanthridine alkaloid sanguinarine in a rat syngeneic model of colorectal cancer. ( Balestrieri, E; Garaci, E; Gaziano, R; Mattei, M; Moroni, G; Moroni, N; Palmieri, G; Pica, F; Serafino, A; Sinibaldi-Vallebona, P; Sorrentino, R, 2012)
"We examined the effects of sanguinarine, a benzophenanthridine alkaloid, on reactive oxygen species (ROS) production and the association of these effects with apoptotic cell death in a human colorectal cancer HCT-116 cell line."3.79Sanguinarine induces apoptosis in human colorectal cancer HCT-116 cells through ROS-mediated Egr-1 activation and mitochondrial dysfunction. ( Choi, YH; Han, MH; Kim, GY; Yoo, YH, 2013)
"To evaluate the in-vivo preclinical antitumor activity of sanguinarine in a rat syngeneic model of colorectal cancer."3.78Antitumor effects of the benzophenanthridine alkaloid sanguinarine in a rat syngeneic model of colorectal cancer. ( Balestrieri, E; Garaci, E; Gaziano, R; Mattei, M; Moroni, G; Moroni, N; Palmieri, G; Pica, F; Serafino, A; Sinibaldi-Vallebona, P; Sorrentino, R, 2012)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gong, X1
Chen, Z1
Han, Q1
Chen, C1
Jing, L1
Liu, Y1
Zhao, L1
Yao, X1
Sun, X1
Han, MH1
Kim, GY1
Yoo, YH1
Choi, YH1
Pica, F1
Balestrieri, E1
Serafino, A1
Sorrentino, R1
Gaziano, R1
Moroni, G1
Moroni, N1
Palmieri, G1
Mattei, M1
Garaci, E1
Sinibaldi-Vallebona, P1

Other Studies

3 other studies available for sanguinarine and Colorectal Cancer

ArticleYear
Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK.
    BMC cancer, 2018, May-21, Volume: 18, Issue:1

    Topics: Animals; Apoptosis; Benzophenanthridines; Biomarkers, Tumor; Colorectal Neoplasms; Female; HCT116 Ce

2018
Sanguinarine induces apoptosis in human colorectal cancer HCT-116 cells through ROS-mediated Egr-1 activation and mitochondrial dysfunction.
    Toxicology letters, 2013, Jul-04, Volume: 220, Issue:2

    Topics: Apoptosis; Benzophenanthridines; Caspases; Colorectal Neoplasms; Early Growth Response Protein 1; HC

2013
Antitumor effects of the benzophenanthridine alkaloid sanguinarine in a rat syngeneic model of colorectal cancer.
    Anti-cancer drugs, 2012, Volume: 23, Issue:1

    Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzoph

2012