sanguinarine has been researched along with Chemical and Drug Induced Liver Injury in 3 studies
benzophenanthridine alkaloid : A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Based on these reports, a safe oral daily dose limit of not more than 2." | 1.51 | Characterization of the cytotoxicity of selected Chelidonium alkaloids in rat hepatocytes. ( Gao, L; Merz, KH; Schmitz, HJ; Schrenk, D, 2019) |
| "Sanguinarine (SANG) has been suggested to be one of the principle constituents responsible for the toxicity of Argemone mexicana seed oil." | 1.35 | Induction of hepatotoxicity by sanguinarine is associated with oxidation of protein thiols and disturbance of mitochondrial respiration. ( Cheah, KP; Chiou, HY; Chiu, WT; Choy, CS; Hu, CM; Li, JS; Liao, JW; Liu, YH; Yong, SF, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, L | 1 |
| Schmitz, HJ | 1 |
| Merz, KH | 1 |
| Schrenk, D | 1 |
| Choy, CS | 1 |
| Cheah, KP | 1 |
| Chiou, HY | 1 |
| Li, JS | 1 |
| Liu, YH | 1 |
| Yong, SF | 1 |
| Chiu, WT | 1 |
| Liao, JW | 1 |
| Hu, CM | 1 |
| Dalvi, RR | 1 |
3 other studies available for sanguinarine and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Characterization of the cytotoxicity of selected Chelidonium alkaloids in rat hepatocytes.
Topics: Alkaloids; Animals; Benzophenanthridines; Berberine; Cells, Cultured; Chelidonium; Chemical and Drug | 2019 |
Induction of hepatotoxicity by sanguinarine is associated with oxidation of protein thiols and disturbance of mitochondrial respiration.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Benzophenanthridines; Cardiotonic Agents; Cells, Culture | 2008 |
Sanguinarine: its potential as a liver toxic alkaloid present in the seeds of Argemone mexicana.
Topics: Alanine Transaminase; Alkaloids; Animals; Aspartate Aminotransferases; Benzophenanthridines; Chemica | 1985 |