sanguinarine has been researched along with Cardiomegaly in 1 studies
benzophenanthridine alkaloid : A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sanguinarine protected against the cardiac hypertrophy, fibrosis and dysfunction induced by AB, as assessed by the heart weight/body weight, lung weight/body weight and heart weight/tibia length ratios, echocardiographic and hemodynamic parameters, histological analysis, and the gene expression levels of hypertrophic and fibrotic markers." | 1.40 | Sanguinarine protects against pressure overload‑induced cardiac remodeling via inhibition of nuclear factor-κB activation. ( Cheng, Z; Deng, W; Fang, Y; He, M; Li, W; Lin, Y; Liu, Y; Sun, D; Tang, Q; Zhang, J; Zhang, R; Zhang, Y; Zhou, H, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, W | 1 |
| Fang, Y | 1 |
| Liu, Y | 1 |
| Zhou, H | 1 |
| Cheng, Z | 1 |
| Zhang, Y | 1 |
| Sun, D | 1 |
| He, M | 1 |
| Lin, Y | 1 |
| Zhang, R | 1 |
| Zhang, J | 1 |
| Li, W | 1 |
| Tang, Q | 1 |
1 other study available for sanguinarine and Cardiomegaly
| Article | Year |
|---|---|
Sanguinarine protects against pressure overload‑induced cardiac remodeling via inhibition of nuclear factor-κB activation.
Topics: Animals; Benzophenanthridines; Cardiomegaly; Echocardiography; Hemodynamics; Isoquinolines; Male; Mi | 2014 |