sanguinarine has been researched along with Breast Cancer in 10 studies
benzophenanthridine alkaloid : A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We explore the effect of sanguinarine on hypoxia-induced activation of Ephrin type-B receptor 4 (EphB4) and hypoxia inducible factor-1α (HIF-1α) pathways in breast cancer." | 8.02 | Sanguinarine combats hypoxia-induced activation of EphB4 and HIF-1α pathways in breast cancer. ( Chen, L; Ghauri, MA; Liu, F; Sarwar, A; Su, Q; Ullah, A; Wang, J; Wu, Q; Zhang, Y, 2021) |
| "A large number of breast cancer patients perishes due to metastasis instead of primary tumor, but molecular mechanisms contributing towards cancer metastasis remain poorly understood." | 5.62 | Sanguinarine impedes metastasis and causes inversion of epithelial to mesenchymal transition in breast cancer. ( Ghauri, MA; Sarwar, A; Su, Q; Ullah, A; Wang, J; Wu, Q; Zhang, D; Zhang, Y, 2021) |
| "Breast cancer is associated with a high mortality rate around the world due to its aggressiveness and high resistance to conventional therapies." | 5.46 | Evaluation of the Anticancer Activities of the Plant Alkaloids Sanguinarine and Chelerythrine in Human Breast Adenocarcinoma Cells. ( Almeida, IV; Biazi, BI; Fernandes, LM; Vicentini, VEP, 2017) |
| "Most complications of breast cancer are attributed to metastasis to distant organs, including lymph nodes, bone, lung and liver." | 5.40 | Sanguinarine inhibits invasiveness and the MMP-9 and COX-2 expression in TPA-induced breast cancer cells by inducing HO-1 expression. ( Jin, ML; Kim, YH; Lee, SJ; Park, G; Park, SY, 2014) |
| "Sanguinarine treatment resulted in a reduction of cell migration, in a dose-dependent inhibition of cell viability and in the induction of cell death by apoptosis in both human (MDA-MB-231 cells) and mouse (A17 cells) in vitro models of BLBC." | 5.40 | Sanguinarine suppresses basal-like breast cancer growth through dihydrofolate reductase inhibition. ( Amici, A; Andreani, C; Bartolacci, C; Belletti, B; Gambini, V; Garulli, C; Giangrossi, M; Iezzi, M; Kalogris, C; Lucci, C; Marchini, C; Pietrella, L; Pucciarelli, S; Tilio, M; Zabaleta, ME, 2014) |
| "We explore the effect of sanguinarine on hypoxia-induced activation of Ephrin type-B receptor 4 (EphB4) and hypoxia inducible factor-1α (HIF-1α) pathways in breast cancer." | 4.02 | Sanguinarine combats hypoxia-induced activation of EphB4 and HIF-1α pathways in breast cancer. ( Chen, L; Ghauri, MA; Liu, F; Sarwar, A; Su, Q; Ullah, A; Wang, J; Wu, Q; Zhang, Y, 2021) |
| "It appears that sub-apoptotic concentrations of sanguinarine can suppress breast cancer cell proliferation for extended lengths of time, and that this effect results from a relatively brief period of activity when the drug is concentrated in the nucleus." | 3.73 | Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine. ( Holy, J; Lamont, G; Perkins, E, 2006) |
| "A large number of breast cancer patients perishes due to metastasis instead of primary tumor, but molecular mechanisms contributing towards cancer metastasis remain poorly understood." | 1.62 | Sanguinarine impedes metastasis and causes inversion of epithelial to mesenchymal transition in breast cancer. ( Ghauri, MA; Sarwar, A; Su, Q; Ullah, A; Wang, J; Wu, Q; Zhang, D; Zhang, Y, 2021) |
| "Breast cancer is associated with a high mortality rate around the world due to its aggressiveness and high resistance to conventional therapies." | 1.46 | Evaluation of the Anticancer Activities of the Plant Alkaloids Sanguinarine and Chelerythrine in Human Breast Adenocarcinoma Cells. ( Almeida, IV; Biazi, BI; Fernandes, LM; Vicentini, VEP, 2017) |
| "Most complications of breast cancer are attributed to metastasis to distant organs, including lymph nodes, bone, lung and liver." | 1.40 | Sanguinarine inhibits invasiveness and the MMP-9 and COX-2 expression in TPA-induced breast cancer cells by inducing HO-1 expression. ( Jin, ML; Kim, YH; Lee, SJ; Park, G; Park, SY, 2014) |
| "Sanguinarine treatment resulted in a reduction of cell migration, in a dose-dependent inhibition of cell viability and in the induction of cell death by apoptosis in both human (MDA-MB-231 cells) and mouse (A17 cells) in vitro models of BLBC." | 1.40 | Sanguinarine suppresses basal-like breast cancer growth through dihydrofolate reductase inhibition. ( Amici, A; Andreani, C; Bartolacci, C; Belletti, B; Gambini, V; Garulli, C; Giangrossi, M; Iezzi, M; Kalogris, C; Lucci, C; Marchini, C; Pietrella, L; Pucciarelli, S; Tilio, M; Zabaleta, ME, 2014) |
| "Sanguinarine is a benzophenanthridine alkaloid that is known to have antimicrobial, anti-inflammatory, antioxidant and anticancer properties." | 1.35 | Sanguinarine, a benzophenanthridine alkaloid, induces apoptosis in MDA-MB-231 human breast carcinoma cells through a reactive oxygen species-mediated mitochondrial pathway. ( Choi, WY; Choi, YH; Kim, GY; Lee, WH, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Malla, RR | 1 |
| Bhamidipati, P | 1 |
| Adem, M | 1 |
| Ghauri, MA | 2 |
| Su, Q | 2 |
| Ullah, A | 2 |
| Wang, J | 2 |
| Sarwar, A | 2 |
| Wu, Q | 2 |
| Zhang, D | 1 |
| Zhang, Y | 2 |
| Chen, L | 1 |
| Liu, F | 1 |
| Dong, XZ | 1 |
| Zhang, M | 1 |
| Wang, K | 1 |
| Liu, P | 1 |
| Guo, DH | 1 |
| Zheng, XL | 1 |
| Ge, XY | 1 |
| Park, SY | 1 |
| Jin, ML | 1 |
| Kim, YH | 1 |
| Lee, SJ | 1 |
| Park, G | 1 |
| Kalogris, C | 1 |
| Garulli, C | 1 |
| Pietrella, L | 1 |
| Gambini, V | 1 |
| Pucciarelli, S | 1 |
| Lucci, C | 1 |
| Tilio, M | 1 |
| Zabaleta, ME | 1 |
| Bartolacci, C | 1 |
| Andreani, C | 1 |
| Giangrossi, M | 1 |
| Iezzi, M | 1 |
| Belletti, B | 1 |
| Marchini, C | 1 |
| Amici, A | 1 |
| Almeida, IV | 1 |
| Fernandes, LM | 1 |
| Biazi, BI | 1 |
| Vicentini, VEP | 1 |
| Choi, WY | 2 |
| Kim, GY | 2 |
| Lee, WH | 2 |
| Choi, YH | 2 |
| Hong, SH | 1 |
| Kim, SO | 1 |
| Yoo, YH | 1 |
| Holy, J | 1 |
| Lamont, G | 1 |
| Perkins, E | 1 |
1 review available for sanguinarine and Breast Cancer
| Article | Year |
|---|---|
Insights into the potential of Sanguinarine as a promising therapeutic option for breast cancer.
Topics: Benzophenanthridines; Breast Neoplasms; Female; Humans; Hypoxia; Isoquinolines; Tumor Microenvironme | 2023 |
9 other studies available for sanguinarine and Breast Cancer
| Article | Year |
|---|---|
Sanguinarine impedes metastasis and causes inversion of epithelial to mesenchymal transition in breast cancer.
Topics: Animals; Benzophenanthridines; Breast Neoplasms; Cell Line, Tumor; Epithelial-Mesenchymal Transition | 2021 |
Sanguinarine combats hypoxia-induced activation of EphB4 and HIF-1α pathways in breast cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzophenanthridines; Breast Neoplasms; Cell Line, Tumor | 2021 |
Sanguinarine inhibits vascular endothelial growth factor release by generation of reactive oxygen species in MCF-7 human mammary adenocarcinoma cells.
Topics: Acetylcysteine; Apoptosis; Benzophenanthridines; Breast Neoplasms; Cell Proliferation; Cell Survival | 2013 |
Sanguinarine inhibits invasiveness and the MMP-9 and COX-2 expression in TPA-induced breast cancer cells by inducing HO-1 expression.
Topics: Anti-Infective Agents; Benzophenanthridines; Breast Neoplasms; Cell Movement; Cyclooxygenase 2; Fema | 2014 |
Sanguinarine suppresses basal-like breast cancer growth through dihydrofolate reductase inhibition.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzophenanthridines; Breast Neoplasms; Cell | 2014 |
Evaluation of the Anticancer Activities of the Plant Alkaloids Sanguinarine and Chelerythrine in Human Breast Adenocarcinoma Cells.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Benzophenanthridines; Breast Neoplasms; Cell Prol | 2017 |
Sanguinarine, a benzophenanthridine alkaloid, induces apoptosis in MDA-MB-231 human breast carcinoma cells through a reactive oxygen species-mediated mitochondrial pathway.
Topics: Apoptosis; Benzophenanthridines; BH3 Interacting Domain Death Agonist Protein; Breast Neoplasms; Cas | 2008 |
Anti-invasive activity of sanguinarine through modulation of tight junctions and matrix metalloproteinase activities in MDA-MB-231 human breast carcinoma cells.
Topics: Antineoplastic Agents; Benzophenanthridines; Breast Neoplasms; Cell Movement; Cell Proliferation; Do | 2009 |
Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine.
Topics: Active Transport, Cell Nucleus; Alkaloids; Antineoplastic Agents, Phytogenic; Apoptosis; Benzophenan | 2006 |