Page last updated: 2024-11-04

sanguinarine and Atherosclerosis

sanguinarine has been researched along with Atherosclerosis in 1 studies

benzophenanthridine alkaloid : A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.

Atherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.

Research Excerpts

ExcerptRelevanceReference
"Sanguinarine treatment of VSMC resulted in significant growth inhibition as a result of G1-phase cell-cycle arrest mediated by induction of p27KIP1 expression, and resulted in a down-regulation of the expression of cyclins and CDKs in VSMC."1.35Sanguinarine-induced G1-phase arrest of the cell cycle results from increased p27KIP1 expression mediated via activation of the Ras/ERK signaling pathway in vascular smooth muscle cells. ( Jung, JH; Kim, SK; Kim, SR; Kim, WJ; Lee, B; Lee, SJ; Moon, SK; Park, SS, 2008)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, B1
Lee, SJ1
Park, SS1
Kim, SK1
Kim, SR1
Jung, JH1
Kim, WJ1
Moon, SK1

Other Studies

1 other study available for sanguinarine and Atherosclerosis

ArticleYear
Sanguinarine-induced G1-phase arrest of the cell cycle results from increased p27KIP1 expression mediated via activation of the Ras/ERK signaling pathway in vascular smooth muscle cells.
    Archives of biochemistry and biophysics, 2008, Mar-15, Volume: 471, Issue:2

    Topics: Alkaloids; Atherosclerosis; Benzophenanthridines; Cell Cycle; Cells, Cultured; Cyclin-Dependent Kina

2008