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sanguinarine and Astrocytoma, Grade IV

sanguinarine has been researched along with Astrocytoma, Grade IV in 1 studies

benzophenanthridine alkaloid : A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.

Research Excerpts

ExcerptRelevanceReference
"The sanguinarine treatment induced the proteolytic activation of caspases and ICAD/DFF45, which was associated with the modulation of the Bcl-2 family, concomitant degradation of poly(ADP ribose) polymerase and phospholipase C-gamma1 protein, and DNA fragmentation."5.34Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt. ( Choi, BT; Choi, YH; Han, MH; Kim, GY; Kim, SO; Kwon, TK; Lee, WH, 2007)
"The sanguinarine treatment induced the proteolytic activation of caspases and ICAD/DFF45, which was associated with the modulation of the Bcl-2 family, concomitant degradation of poly(ADP ribose) polymerase and phospholipase C-gamma1 protein, and DNA fragmentation."1.34Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt. ( Choi, BT; Choi, YH; Han, MH; Kim, GY; Kim, SO; Kwon, TK; Lee, WH, 2007)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Han, MH1
Kim, SO1
Kim, GY1
Kwon, TK1
Choi, BT1
Lee, WH1
Choi, YH1

Other Studies

1 other study available for sanguinarine and Astrocytoma, Grade IV

ArticleYear
Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt.
    Anti-cancer drugs, 2007, Volume: 18, Issue:8

    Topics: Alkaloids; Animals; Annexin A5; Apoptosis; Benzophenanthridines; Blotting, Western; Caspases; Cell L

2007