Page last updated: 2024-11-04

sanguinarine and Acute Liver Injury, Drug-Induced

sanguinarine has been researched along with Acute Liver Injury, Drug-Induced in 3 studies

benzophenanthridine alkaloid : A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.

Research Excerpts

ExcerptRelevanceReference
" Based on these reports, a safe oral daily dose limit of not more than 2."1.51Characterization of the cytotoxicity of selected Chelidonium alkaloids in rat hepatocytes. ( Gao, L; Merz, KH; Schmitz, HJ; Schrenk, D, 2019)
"Sanguinarine (SANG) has been suggested to be one of the principle constituents responsible for the toxicity of Argemone mexicana seed oil."1.35Induction of hepatotoxicity by sanguinarine is associated with oxidation of protein thiols and disturbance of mitochondrial respiration. ( Cheah, KP; Chiou, HY; Chiu, WT; Choy, CS; Hu, CM; Li, JS; Liao, JW; Liu, YH; Yong, SF, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, L1
Schmitz, HJ1
Merz, KH1
Schrenk, D1
Choy, CS1
Cheah, KP1
Chiou, HY1
Li, JS1
Liu, YH1
Yong, SF1
Chiu, WT1
Liao, JW1
Hu, CM1
Dalvi, RR1

Other Studies

3 other studies available for sanguinarine and Acute Liver Injury, Drug-Induced

ArticleYear
Characterization of the cytotoxicity of selected Chelidonium alkaloids in rat hepatocytes.
    Toxicology letters, 2019, Sep-01, Volume: 311

    Topics: Alkaloids; Animals; Benzophenanthridines; Berberine; Cells, Cultured; Chelidonium; Chemical and Drug

2019
Induction of hepatotoxicity by sanguinarine is associated with oxidation of protein thiols and disturbance of mitochondrial respiration.
    Journal of applied toxicology : JAT, 2008, Volume: 28, Issue:8

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Benzophenanthridines; Cardiotonic Agents; Cells, Culture

2008
Sanguinarine: its potential as a liver toxic alkaloid present in the seeds of Argemone mexicana.
    Experientia, 1985, Jan-15, Volume: 41, Issue:1

    Topics: Alanine Transaminase; Alkaloids; Animals; Aspartate Aminotransferases; Benzophenanthridines; Chemica

1985