salubrinal has been researched along with Anemia* in 1 studies
1 other study(ies) available for salubrinal and Anemia
Article | Year |
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Salubrinal, a novel inhibitor of eIF-2α dephosphorylation, promotes erythropoiesis at early stage targeted by ufmylation pathway.
Ufmylation was proved to play a crucial role in hematopoietic stem cell (HSC) survival and erythroid differentiation, ufmylation deficiency induces acute anemia and lethality of embryos and adults in mouse models. To screen some compounds to rescue phenotypes induced by gene deletion, in this study, we used DDRGK1 Topics: Anemia; Animals; Cinnamates; Erythrocytes; Erythropoiesis; Eukaryotic Initiation Factor-2; Fetus; Hemolysis; Liver; Male; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Phenotype; Phenylhydrazines; Phosphorylation; Protein Processing, Post-Translational; Thiourea; Up-Regulation | 2019 |