salsoline has been researched along with Parkinson Disease in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (55.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, Y; Ke, M; Wu, H; Xie, B | 1 |
| Deng, YL; Liu, XQ; Qing, H; Wang, R; Zheng, XL | 1 |
| Dostert, P; Maruyama, W; Matsubara, K; Naoi, M | 1 |
| Kajita, M; Nagatsu, T; Niwa, T; Takeda, N; Tatematsu, A; Watanabe, K; Yoshizumi, H | 1 |
| Abe, T; Dostert, P; Maruyama, W; Naoi, M; Tohgi, H | 1 |
| Dostert, P; Hashizume, Y; Maruyama, W; Naoi, M | 1 |
| Dostert, P; Hashizume, Y; Kasamatsu, T; Kohda, K; Maruyama, W; Naoi, M; Takahashi, T | 1 |
| Deleu, D | 1 |
| Abe, T; Maruyama, W; Naoi, M; Tohgi, H | 1 |
| Akao, Y; Maruyama, W; Nakagawa, Y; Naoi, M; Takahashi, T | 2 |
| Maruyama, W; Naoi, M | 4 |
| Maruyama, W; Naoi, M; Strolin-Benedetti, M | 1 |
| Maruyama, W; Naoi, M; Yagi, K; Youdim, M | 1 |
| Akao, Y; Davis, BA; Maruyama, W; Naoi, M; Youdim, MB | 1 |
| Maruyama, W | 1 |
| Dostert, P; Maruyama, W; Nagatsu, T; Nakahara, D; Naoi, M; Niwa, T; Takahashi, A; Takeda, N; Tatematsu, A; Yoshizumi, H | 1 |
3 review(s) available for salsoline and Parkinson Disease
| Article | Year |
|---|---|
N-methyl-(R)salsolinol as a dopaminergic neurotoxin: from an animal model to an early marker of Parkinson's disease.
Topics: Animals; Biomarkers; Brain; Cell Line; Cell Survival; Dopamine; Humans; Isoquinolines; Male; Neurotoxins; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rats, Wistar; Salsoline Alkaloids; Stereoisomerism; Tetrahydroisoquinolines | 1997 |
N-methyl(R)salsolinol, a dopamine neurotoxin, in Parkinson's disease.
Topics: Corpus Striatum; Dopamine; Humans; Isoquinolines; Neurotoxins; Parkinson Disease; Salsoline Alkaloids; Substantia Nigra; Tetrahydroisoquinolines | 1999 |
[Studies on endogenous toxins as pathogenic factors in idiopathic parkinson's disease].
Topics: Aging; Animals; Apoptosis; Dopamine; Humans; Methyltransferases; Mitochondria; Neurotoxins; Pargyline; Parkinson Disease; Propylamines; Salsoline Alkaloids; Tetrahydroisoquinolines | 2000 |
17 other study(ies) available for salsoline and Parkinson Disease
| Article | Year |
|---|---|
High-fat diet causes increased endogenous neurotoxins and phenotype of Parkinson's disease in mice.
Topics: Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucose Intolerance; Isoquinolines; Malondialdehyde; Mice; Neurotoxins; Parkinson Disease; Salsoline Alkaloids | 2019 |
Iron contributes to the formation of catechol isoquinolines and oxidative toxicity induced by overdose dopamine in dopaminergic SH-SY5Y cells.
Topics: Apoptosis; Catechols; Cell Line, Tumor; Cell Survival; Dopamine; Dose-Response Relationship, Drug; Humans; Hydroxyl Radical; Iron; Iron Metabolism Disorders; Isoquinolines; Malondialdehyde; Models, Biological; Nerve Degeneration; Neurons; Neurotoxins; Oxidative Stress; Parkinson Disease; Salsoline Alkaloids; Up-Regulation | 2008 |
N-methyl(R)salsolinol produces hydroxyl radicals: involvement to neurotoxicity.
Topics: Animals; Ascorbic Acid; Catalase; Chromatography, High Pressure Liquid; Dopamine; Ferric Compounds; Ferrous Compounds; Free Radicals; Glutathione; Humans; Hydroxyl Radical; Isoquinolines; Methylation; Neurons; Oxidation-Reduction; Parkinson Disease; Salsoline Alkaloids; Superoxide Dismutase; Tetrahydroisoquinolines | 1995 |
Presence of N-methyldopamine in parkinsonian and normal human brains.
Topics: Brain; Deoxyepinephrine; Gas Chromatography-Mass Spectrometry; Humans; Isoquinolines; Parkinson Disease; Salsoline Alkaloids; Tetrahydroisoquinolines | 1993 |
A dopaminergic neurotoxin, (R)-N-methylsalsolinol, increases in Parkinsonian cerebrospinal fluid.
Topics: Aged; Animals; Brain; Chromatography, High Pressure Liquid; Dopamine; Female; Homovanillic Acid; Humans; Male; Middle Aged; Neurotoxins; Parkinson Disease; Rats; Salsoline Alkaloids; Tetrahydroisoquinolines | 1996 |
An endogenous dopaminergic neurotoxin, N-methyl-(R)-salsolinol, induces DNA damage in human dopaminergic neuroblastoma SH-SY5Y cells.
Topics: Antioxidants; Apoptosis; Carcinogens; Catalase; Cycloheximide; DNA Damage; Dopamine; Free Radicals; Humans; Microscopy, Fluorescence; Neuroblastoma; Neuroprotective Agents; Neurotoxins; Oxidation-Reduction; Parkinson Disease; Protein Synthesis Inhibitors; Salsoline Alkaloids; Selegiline; Semicarbazides; Stereoisomerism; Tetrahydroisoquinolines; Tumor Cells, Cultured | 1997 |
Endogenous dopamine-derived neurotoxins and Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis; Dopamine; Humans; Isoquinolines; Methyltransferases; MPTP Poisoning; Nerve Tissue Proteins; Neurotoxins; Parkinson Disease; Parkinson Disease, Secondary; Rats; Salsoline Alkaloids; Substantia Nigra; Tetrahydroisoquinolines; Tyrosine 3-Monooxygenase | 1998 |
An endogenous MPTP-like dopaminergic neurotoxin, N-methyl(R)salsolinol, in the cerebrospinal fluid decreases with progression of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aged; Biomarkers; Disease Progression; Dopamine Agents; Female; Humans; Male; Middle Aged; Neurotoxins; Parkinson Disease; Salsoline Alkaloids; Tetrahydroisoquinolines | 1999 |
Apoptosis induced by an endogenous neurotoxin, N-methyl(R)salsolinol, is mediated by activation of caspase 3.
Topics: Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; DNA Fragmentation; Enzyme Activation; Enzyme Precursors; Humans; Neurotoxins; Oligopeptides; Parkinson Disease; Salsoline Alkaloids; Tetrahydroisoquinolines; Tumor Cells, Cultured | 1999 |
Cell death of dopamine neurons in aging and Parkinson's disease.
Topics: Adult; Aged; Aging; Apoptosis; Brain; Cerebrospinal Fluid; DNA Damage; DNA, Neoplasm; Female; Humans; Male; Methyltransferases; Middle Aged; Neuroblastoma; Neurons; Neurotoxins; Oxidative Stress; Parkinson Disease; Reactive Oxygen Species; Receptors, Dopamine; Salsoline Alkaloids; Tetrahydroisoquinolines; Tumor Cells, Cultured | 1999 |
N-methyl(R)salsolinol and a neutral N-methyltransferase as pathogenic factors in Parkinson's disease.
Topics: Aged; Analysis of Variance; Antiparkinson Agents; Brain; Female; Homovanillic Acid; Humans; Levodopa; Lymphocytes; Male; Methyltransferases; Middle Aged; Parkinson Disease; Salsoline Alkaloids; Statistics, Nonparametric; Tetrahydroisoquinolines | 2000 |
Anti-apoptotic function of L-(-)deprenyl (Selegiline) and related compounds.
Topics: Antioxidants; Antiparkinson Agents; Apoptosis; DNA Damage; DNA Fragmentation; Humans; Neurotoxins; Parkinson Disease; Salsoline Alkaloids; Selegiline; Structure-Activity Relationship; Tetrahydroisoquinolines; Tumor Cells, Cultured | 2000 |
Involvement of endogenous N-methyl(R)salsolinol in Parkinson's disease: induction of apoptosis and protection by (-)deprenyl.
Topics: Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Dopamine; Enzyme Activation; Female; Humans; Male; Neuroprotective Agents; Oligopeptides; Parkinson Disease; Salsoline Alkaloids; Selegiline; Tetrahydroisoquinolines; Tumor Cells, Cultured | 2000 |
Future of neuroprotection in Parkinson's disease.
Topics: Apoptosis; Humans; Molsidomine; Neuroprotective Agents; Neurotoxins; Nitric Oxide Donors; Oxidopamine; Parkinson Disease; Propylamines; Salsoline Alkaloids; Selegiline; Tetrahydroisoquinolines; Tumor Cells, Cultured | 2001 |
Transfection-enforced Bcl-2 overexpression and an anti-Parkinson drug, rasagiline, prevent nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase induced by an endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol.
Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Cell Line; Cell Nucleus; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Immunoblotting; Immunohistochemistry; Indans; Membrane Potentials; Mitochondria; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Proto-Oncogene Proteins c-bcl-2; Salsoline Alkaloids; Signal Transduction; Tetrahydroisoquinolines; Transfection | 2001 |
[Pathogenesis of idiopathic Parkinson's disease].
Topics: Apoptosis; Brain; Humans; Methyltransferases; Neuroprotective Agents; Parkinson Disease; Salsoline Alkaloids; Tetrahydroisoquinolines | 2001 |
Endogenous synthesis of N-methylsalsolinol, an analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, in rat brain during in vivo microdialysis with salsolinol, as demonstrated by gas chromatography-mass spectrometry.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Gas Chromatography-Mass Spectrometry; Isoquinolines; Male; Methylation; Parkinson Disease; Perfusion; Rats; Rats, Wistar; Salsoline Alkaloids; Tetrahydroisoquinolines | 1992 |