salophen has been researched along with Leukemia in 3 studies
salophen: structure given in first source
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The activity of N,N'-bis(salicylidene)-1,2-phenylenediamine (salophene, 1), its iron(II/III) and manganese(II/III) complexes as well as rac-trans-N,N'-bis(salicylidene)-1,2-cyclohexanediamine (saldach, 2) and its respective iron(II/III) complexes was evaluated against U-937 non-Hodgkin's lymphoma and the HL-60, SUP-B15, and K-562 leukemia cell lines." | 7.77 | Effects of metal salophene and saldach complexes on lymphoma and leukemia cells. ( Gust, R; Hille, A; Kircher, B; Ott, I; Schumacher, P; Wolf, T, 2011) |
| " The activity of N,N'-bis(salicylidene)-1,2-phenylenediamine (salophene, 1), its iron(II/III) and manganese(II/III) complexes as well as rac-trans-N,N'-bis(salicylidene)-1,2-cyclohexanediamine (saldach, 2) and its respective iron(II/III) complexes was evaluated against U-937 non-Hodgkin's lymphoma and the HL-60, SUP-B15, and K-562 leukemia cell lines." | 3.77 | Effects of metal salophene and saldach complexes on lymphoma and leukemia cells. ( Gust, R; Hille, A; Kircher, B; Ott, I; Schumacher, P; Wolf, T, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, BN | 1 |
| Baecker, D | 1 |
| Descher, H | 1 |
| Brandstaetter, P | 1 |
| Hermann, M | 1 |
| Kircher, B | 2 |
| Gust, R | 3 |
| Lee, SY | 1 |
| Hille, A | 2 |
| Kitanovic, I | 1 |
| Jesse, P | 1 |
| Henze, G | 1 |
| Wölfl, S | 1 |
| Prokop, A | 1 |
| Wolf, T | 1 |
| Schumacher, P | 1 |
| Ott, I | 1 |
3 other studies available for salophen and Leukemia
| Article | Year |
|---|---|
Synthesis and biological evaluation of salophen nickel(II) and cobalt(III) complexes as potential anticancer compounds.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cobalt; Female; Ferric Compounds; Humans; Leukemia; Nickel; | 2023 |
[Fe(III)(salophene)Cl], a potent iron salophene complex overcomes multiple drug resistance in lymphoma and leukemia cells.
Topics: Apoptosis; Biomarkers, Tumor; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Daunorubicin; | 2011 |
Effects of metal salophene and saldach complexes on lymphoma and leukemia cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclohexylamines; Dose-Respo | 2011 |