Page last updated: 2024-11-04

salmeterol xinafoate and Asthma, Bronchial

salmeterol xinafoate has been researched along with Asthma, Bronchial in 6 studies

salmeterol : A racemate consisting of equal parts of (R)- and (S)-salmeterol. It is a potent and selective beta2-adrenoceptor agonist (EC50 = 5.3 nM). Unlike other beta2 agonists, it binds to the exo-site domain of beta2 receptors, producing a slow onset of action and prolonged activation.
2-(hydroxymethyl)-4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)phenol : A phenol having a hydroxymethyl group at C-2 and a 1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl group at C-4; derivative of phenylethanolamine.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Brown, AD2
Bunnage, ME2
Glossop, PA2
Holbrook, M1
Jones, RD1
Lane, CA2
Lewthwaite, RA2
Mantell, S1
Perros-Huguet, C2
Price, DA2
Webster, R2
James, K1
Yeadon, M1
Trevethick, MA1
Clarke, NP1
Jones, RM1
Burrows, JL1
Feeder, N1
Taylor, SC1
Spence, FJ1
Alcaraz, L1
Bailey, A1
Cadogan, E1
Connolly, S1
Jewell, R1
Jordan, S1
Kindon, N1
Lister, A1
Lawson, M1
Mullen, A1
Dainty, I1
Nicholls, D1
Paine, S1
Pairaudeau, G1
Stocks, MJ1
Thorne, P1
Young, A1
Jacobsen, JR2
Choi, SK1
Combs, J1
Fournier, EJ1
Klein, U2
Pfeiffer, JW2
Thomas, GR2
Yu, C2
Moran, EJ2
McKinnell, RM1
Linsell, MS1
Nodwell, MB1
Xing, G1
Woo, AY1
Pan, L1
Lin, B1
Cheng, MS1

Reviews

1 review available for salmeterol xinafoate and Asthma, Bronchial

ArticleYear
Recent Advances in β
    Journal of medicinal chemistry, 2020, 12-24, Volume: 63, Issue:24

    Topics: Adrenergic beta-2 Receptor Agonists; Asthma; Clinical Trials as Topic; Heart Failure; Humans; Muscle

2020

Other Studies

5 other studies available for salmeterol xinafoate and Asthma, Bronchial

ArticleYear
The discovery of indole-derived long acting beta2-adrenoceptor agonists for the treatment of asthma and COPD.
    Bioorganic & medicinal chemistry letters, 2007, Nov-15, Volume: 17, Issue:22

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Asthma; Biological Availability; Caco-2 Cells; CHO Cel

2007
Inhalation by design: novel ultra-long-acting β(2)-adrenoreceptor agonists for inhaled once-daily treatment of asthma and chronic obstructive pulmonary disease that utilize a sulfonamide agonist headgroup.
    Journal of medicinal chemistry, 2010, Sep-23, Volume: 53, Issue:18

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals;

2010
From libraries to candidate: the discovery of new ultra long-acting dibasic β₂-adrenoceptor agonists.
    Bioorganic & medicinal chemistry letters, 2012, Jan-01, Volume: 22, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Asthma; Bronchodilator Agents; Cell Line, Tumor; Chemistry, Pharm

2012
A multivalent approach to the discovery of long-acting β(2)-adrenoceptor agonists for the treatment of asthma and COPD.
    Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2

    Topics: Adrenergic beta-2 Receptor Agonists; Animals; Anti-Asthmatic Agents; Asthma; Cell Line; Drug Discove

2012
Discovery of TD-4306, a long-acting β2-agonist for the treatment of asthma and COPD.
    Bioorganic & medicinal chemistry letters, 2014, Jul-01, Volume: 24, Issue:13

    Topics: Adrenergic beta-2 Receptor Agonists; Animals; Asthma; Cell Line; Diphenylamine; Disease Models, Anim

2014