Page last updated: 2024-11-04

salicylsalicylic acid and Fatty Liver, Nonalcoholic

salicylsalicylic acid has been researched along with Fatty Liver, Nonalcoholic in 2 studies

salicylsalicylic acid: structure
salsalate : A dimeric benzoate ester obtained by intermolecular condensation between the carboxy of one molecule of salicylic acid with the phenol group of a second. It is a prodrug for salycylic acid that is used for treatment of rheumatoid arthritis and osteoarthritis and also shows activity against type II diabetes.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Li, J1
Chen, C1
Zhang, W1
Bi, J1
Yang, G1
Li, E1
Liang, W1
Verschuren, L1
Mulder, P1
van der Hoorn, JW1
Verheij, J1
van Dam, AD1
Boon, MR1
Princen, HM1
Havekes, LM1
Kleemann, R1
van den Hoek, AM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Comparison of Effect Between Salsalate and Placebo in Osteoarthritis With Nonalcoholic Fatty Liver Disease: Investigator Initiated Randomized Placebo-controlled Double-blind, Pilot Study[NCT03222206]Phase 434 participants (Actual)Interventional2017-11-08Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for salicylsalicylic acid and Fatty Liver, Nonalcoholic

ArticleYear
Salsalate reverses metabolic disorders in a mouse model of non-alcoholic fatty liver disease through AMPK activation and caspase-6 activity inhibition.
    Basic & clinical pharmacology & toxicology, 2021, Volume: 128, Issue:3

    Topics: Adipogenesis; AMP-Activated Protein Kinases; Animals; Caspase 6; Caspase Inhibitors; Diet, High-Fat;

2021
Salsalate attenuates diet induced non-alcoholic steatohepatitis in mice by decreasing lipogenic and inflammatory processes.
    British journal of pharmacology, 2015, Volume: 172, Issue:22

    Topics: Alanine Transaminase; Animals; Apolipoproteins E; Aspartate Aminotransferases; Blood Glucose; Body W

2015