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salicylsalicylic acid and Disease Models, Animal

salicylsalicylic acid has been researched along with Disease Models, Animal in 9 studies

salicylsalicylic acid: structure
salsalate : A dimeric benzoate ester obtained by intermolecular condensation between the carboxy of one molecule of salicylic acid with the phenol group of a second. It is a prodrug for salycylic acid that is used for treatment of rheumatoid arthritis and osteoarthritis and also shows activity against type II diabetes.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
" The disposition of SS and SA were evaluated simultaneously using a pharmacokinetic model comprising several transit absorption steps and linear and nonlinear dual elimination pathways for SA."1.38Pharmacokinetics of salsalate and salicylic acid in normal and diabetic rats. ( Almon, RR; Cao, Y; DuBois, DC; Jusko, WJ, 2012)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's6 (66.67)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Leonhard, WN1
Song, X1
Kanhai, AA1
Iliuta, IA1
Bozovic, A1
Steinberg, GR1
Peters, DJM1
Pei, Y1
Li, J1
Chen, C1
Zhang, W1
Bi, J1
Yang, G1
Li, E1
Davidson, EP1
Coppey, LJ1
Shevalye, H1
Obrosov, A1
Yorek, MA1
Jung, TW1
Youn, BS1
Choi, HY1
Lee, SY1
Hong, HC1
Yang, SJ1
Yoo, HJ1
Kim, BH1
Baik, SH1
Choi, KM1
Panza, F1
Solfrizzi, V1
Seripa, D1
Imbimbo, BP1
Lozupone, M1
Santamato, A1
Tortelli, R1
Galizia, I1
Prete, C1
Daniele, A1
Pilotto, A1
Greco, A1
Logroscino, G1
Shrestha, S1
Bhattarai, BR1
Kafle, B1
Lee, KH1
Cho, H1
Cao, Y2
Dubois, DC2
Sun, H1
Almon, RR2
Jusko, WJ2

Other Studies

9 other studies available for salicylsalicylic acid and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Salsalate, but not metformin or canagliflozin, slows kidney cyst growth in an adult-onset mouse model of polycystic kidney disease.
    EBioMedicine, 2019, Volume: 47

    Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Cyclic AMP;

2019
Salsalate reverses metabolic disorders in a mouse model of non-alcoholic fatty liver disease through AMPK activation and caspase-6 activity inhibition.
    Basic & clinical pharmacology & toxicology, 2021, Volume: 128, Issue:3

    Topics: Adipogenesis; AMP-Activated Protein Kinases; Animals; Caspase 6; Caspase Inhibitors; Diet, High-Fat;

2021
Effect of Dietary Content of Menhaden Oil with or without Salsalate on Neuropathic Endpoints in High-Fat-Fed/Low-Dose Streptozotocin-Treated Sprague Dawley Rats.
    Journal of diabetes research, 2018, Volume: 2018

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Diet; Diet, Fat-Rest

2018
Salsalate and adiponectin ameliorate hepatic steatosis by inhibition of the hepatokine fetuin-A.
    Biochemical pharmacology, 2013, Oct-01, Volume: 86, Issue:7

    Topics: Adiponectin; alpha-2-HS-Glycoprotein; AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Diseas

2013
Tau-based therapeutics for Alzheimer's disease: active and passive immunotherapy.
    Immunotherapy, 2016, Volume: 8, Issue:9

    Topics: Acetylation; Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monocl

2016
Derivatives of 1,4-bis(3-hydroxycarbonyl-4-hydroxyl)styrylbenzene as PTP1B inhibitors with hypoglycemic activity.
    Bioorganic & medicinal chemistry, 2008, Sep-15, Volume: 16, Issue:18

    Topics: Animals; Anti-Obesity Agents; Blood Glucose; Disease Models, Animal; Fasting; Glucose Tolerance Test

2008
Modeling diabetes disease progression and salsalate intervention in Goto-Kakizaki rats.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Diabetes Mellitus, Typ

2011
Pharmacokinetics of salsalate and salicylic acid in normal and diabetic rats.
    Biopharmaceutics & drug disposition, 2012, Volume: 33, Issue:6

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Dia

2012