salicylsalicylic acid has been researched along with Deficiency, Vitamin D in 1 studies
salicylsalicylic acid: structure
salsalate : A dimeric benzoate ester obtained by intermolecular condensation between the carboxy of one molecule of salicylic acid with the phenol group of a second. It is a prodrug for salycylic acid that is used for treatment of rheumatoid arthritis and osteoarthritis and also shows activity against type II diabetes.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jablonski, KL | 1 |
| Chonchol, M | 1 |
| Pierce, GL | 1 |
| Walker, AE | 1 |
| Seals, DR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Targeting Inflammation to Treat Cardiovascular Aging in Humans (TIVA Study)[NCT01775865] | Phase 2 | 59 participants (Actual) | Interventional | 2012-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Endothelial function (NCT01775865)
Timeframe: Change from baseline brachial artery FMD at 4 weeks
| Intervention | Percent dilation (Mean) | |
|---|---|---|
| Baseline | 4 Weeks | |
| Placebo | 3.57 | 2.50 |
| Salsalate | 3.49 | 4.60 |
| Young Control Group | 5.88 | NA |
Aortic stiffness (NCT01775865)
Timeframe: Change in CFPWV from baseline at 4 weeks
| Intervention | cm/sec (Mean) | |
|---|---|---|
| Baseline | 4 weeks | |
| Placebo | 785.1 | 740.01 |
| Salsalate | 831.3 | 839.6 |
| Young Control Group | 538.0 | NA |
1 other study available for salicylsalicylic acid and Deficiency, Vitamin D
| Article | Year |
|---|---|
25-Hydroxyvitamin D deficiency is associated with inflammation-linked vascular endothelial dysfunction in middle-aged and older adults.
Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Aged; Brachial Artery; Endothelium, Vascular; Female; Huma | 2011 |