salicylsalicylic acid has been researched along with Atherogenesis in 3 studies
salicylsalicylic acid: structure
salsalate : A dimeric benzoate ester obtained by intermolecular condensation between the carboxy of one molecule of salicylic acid with the phenol group of a second. It is a prodrug for salycylic acid that is used for treatment of rheumatoid arthritis and osteoarthritis and also shows activity against type II diabetes.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bigford, GE | 1 |
| Szeto, A | 1 |
| Kimball, J | 1 |
| Herderick, EE | 1 |
| Mendez, AJ | 1 |
| Nash, MS | 1 |
| Jung, TW | 1 |
| Park, HS | 1 |
| Jeong, JH | 1 |
| Lee, T | 1 |
| Nohria, A | 1 |
| Kinlay, S | 1 |
| Buck, JS | 1 |
| Redline, W | 1 |
| Copeland-Halperin, R | 1 |
| Kim, S | 1 |
| Beckman, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inflammation and Vascular Function in Atherosclerosis[NCT00760019] | Phase 2/Phase 3 | 58 participants (Actual) | Interventional | 2005-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Flow-mediated, endothelium-dependent vasodilation (percentage increase in brachial artery diameter after a 5 minute ischemic stimulus) measured at the end of placebo treatment and end of salsalate treatment were compared. (NCT00760019)
Timeframe: Upon completion of 4 weeks of salsalate and placebo treatment
| Intervention | percentage vasodilation (Median) |
|---|---|
| Salsalate | 6.8 |
| Placebo | 8.7 |
1 trial available for salicylsalicylic acid and Atherogenesis
| Article | Year |
|---|---|
The effect of salsalate therapy on endothelial function in a broad range of subjects.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Biomarkers; Boston; Cross-Ove | 2014 |
2 other studies available for salicylsalicylic acid and Atherogenesis
| Article | Year |
|---|---|
Cardiometabolic risks and atherosclerotic disease in ApoE knockout mice: Effect of spinal cord injury and Salsalate anti-inflammatory pharmacotherapy.
Topics: Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Atherosclerosis; Body Weight; Cardiometabolic Ri | 2021 |
Salsalate ameliorates the atherosclerotic response through HO-1- and SIRT1-mediated suppression of ER stress and inflammation.
Topics: Atherosclerosis; Chemokine CCL2; Endoplasmic Reticulum Stress; Heme Oxygenase-1; Human Umbilical Vei | 2019 |