salicylic acid has been researched along with Neurofibromatosis 1 in 25 studies
Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).
Neurofibromatosis 1: An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Plexiform neurofibroma is a characteristic lesion of Von Recklinghausen's disease." | 1.56 | [Management of cervico-cephalic plexiform neurofibromas: About 35 cases]. ( Foba, ML; Ndiaye, AÏ; Ndiaye, L; Sankalé, AA, 2020) |
| "Internal plexiform neurofibromas are a major cause of adverse outcomes in patients with neurofibromatosis 1 (NF1)." | 1.42 | Quantitative associations of scalp and body subcutaneous neurofibromas with internal plexiform tumors in neurofibromatosis 1. ( Arman, D; Birch, P; Chohan, H; Farschtschi, S; Friedman, JM; Fuensterer, C; Jett, K; Kluwe, L; Mautner, VF; Nguyen, R, 2015) |
| "The first case had an associated meningoencephalocele, and the second had large vascular channels within the lesion and the dominant ipsilateral transverse sinus lying in the center of the calvarial defect." | 1.39 | Congenital giant plexiform neurofibroma with occipital calvarial dysplasia in association with meningoencephalocele in neurofibromatosis Type 1 and segmental neurofibromatosis: report of 2 cases. ( Dadlani, R; Ghosal, N; Hegde, AS; Sadanand, V, 2013) |
| "These characteristics confirmed gliomatosis cerebri." | 1.38 | Subcutaneous tumor seeding after biopsy in gliomatosis cerebri. ( Buis, DR; De Witt Hamer, PC; van der Valk, P, 2012) |
| "Malignant peripheral nerve sheath tumors (MPNST) constitute a group of soft tissue neoplasms with neurogenic origin." | 1.38 | Giant malignant peripheral nerve sheath tumor of the scalp. ( A M M, A; B A, de L; F, T; G H T S, B; H, C; R C, L; T C C, C, 2012) |
| "The association of Von Recklinghausen's disease and soft tissue sarcoma is rare: most often neurofibroma which degenerates is observed." | 1.33 | [Large bilateral lung opacities]. ( Abdelghani, A; Benzarti, M; Garrouche, A; Hayouni, A; Jerray, M; Mezghani, S; Trabelsi, A, 2005) |
| "A 62-year-old man with neurofibromatosis type 1 presented with rapid growth of a scalp mass." | 1.31 | Rapid expansion of benign scalp neurofibroma caused by massive intratumoral hemorrhage--case report. ( Haraoka, S; Kazekawa, K; Nii, K; Nomoto, Y; Tanaka, A; Tsutsumi, M; Ueno, Y, 2002) |
| "We presented a case of neurofibromatosis type I (NF-1) associated with an extracranial arteriovenous fistula (AVF) fed by the occipital and vertebral artery." | 1.31 | [Combination of intravascular surgery and surgical operation for occipital subcutaneous arteriovenous fistula in a patient with neurofibromatosis type I]. ( Abe, T; Hasegawa, Y; Hayashi, J; Kanki, T; Tanaka, T; Ui, K; Usami, S, 2002) |
| "These 9 cases confirm that tuberose sclerosis, von Recklinghausen's neurofibromatosis, incontinentia pigmenti, linear warty sebaceous naevus and alopecic naevus resulting in a woolly naevus of the scalp may be complicated by flexion spasms with hypsarhythmia." | 1.26 | [Dermo-neuro-hypsarrhythmia. Association of a congenital dermatosis and hypsarthymia. 9 cases (author's transl)]. ( Beauvais, P; Bressieux, JM; Larrègue, M; Lauret, P, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (20.00) | 18.7374 |
| 1990's | 4 (16.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 10 (40.00) | 24.3611 |
| 2020's | 2 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baldawa, S | 1 |
| Chimanchode, G | 1 |
| Vora, N | 1 |
| Ndiaye, L | 1 |
| Ndiaye, AÏ | 1 |
| Foba, ML | 1 |
| Sankalé, AA | 1 |
| Dadlani, R | 1 |
| Sadanand, V | 1 |
| Ghosal, N | 1 |
| Hegde, AS | 1 |
| Jett, K | 2 |
| Nguyen, R | 1 |
| Arman, D | 1 |
| Birch, P | 1 |
| Chohan, H | 1 |
| Farschtschi, S | 1 |
| Fuensterer, C | 1 |
| Kluwe, L | 1 |
| Friedman, JM | 2 |
| Mautner, VF | 1 |
| Yunoki, M | 1 |
| Hiramatsu, M | 1 |
| Hirashita, K | 1 |
| Gohda, Y | 1 |
| Yoshino, K | 1 |
| Fujimoto, S | 1 |
| Tanaka, H | 1 |
| Mizobuchi, K | 1 |
| Takata, K | 1 |
| Morito, T | 1 |
| Patel, RR | 1 |
| Meehan, S | 1 |
| Orlow, SJ | 1 |
| Ge, P | 1 |
| Fu, S | 1 |
| Lu, L | 1 |
| Zhong, Y | 1 |
| Qi, B | 1 |
| Luo, Y | 1 |
| Nemeur, A | 1 |
| Combemale, P | 1 |
| Souteyrand, P | 1 |
| D'Incan, M | 1 |
| Smith, M | 1 |
| Heran, MK | 1 |
| Connolly, MB | 1 |
| Heran, HK | 1 |
| Lyons, CJ | 1 |
| Steinbok, P | 1 |
| Armstrong, L | 1 |
| Buis, DR | 1 |
| van der Valk, P | 1 |
| De Witt Hamer, PC | 1 |
| Bhaskar, S | 1 |
| Sobti, S | 1 |
| Singh, AK | 1 |
| F, T | 1 |
| A M M, A | 1 |
| B A, de L | 1 |
| T C C, C | 1 |
| R C, L | 1 |
| G H T S, B | 1 |
| H, C | 1 |
| Tsutsumi, M | 1 |
| Kazekawa, K | 1 |
| Tanaka, A | 1 |
| Ueno, Y | 1 |
| Nomoto, Y | 1 |
| Nii, K | 1 |
| Haraoka, S | 1 |
| Niijima, K | 1 |
| Mezghani, S | 1 |
| Abdelghani, A | 1 |
| Trabelsi, A | 1 |
| Hayouni, A | 1 |
| Garrouche, A | 1 |
| Benzarti, M | 1 |
| Jerray, M | 1 |
| Tanaka, T | 1 |
| Hasegawa, Y | 1 |
| Kanki, T | 1 |
| Hayashi, J | 1 |
| Ui, K | 1 |
| Usami, S | 1 |
| Abe, T | 1 |
| Larrègue, M | 1 |
| Lauret, P | 1 |
| Beauvais, P | 1 |
| Bressieux, JM | 1 |
| Becker, DW | 1 |
| Fesel, R | 1 |
| Plewig, G | 1 |
| Lentrodt, J | 1 |
| Trattner, A | 1 |
| David, M | 1 |
| Hodak, E | 1 |
| Ben-David, E | 1 |
| Sandbank, M | 1 |
| Koransky, J | 1 |
| Duchateau, J | 1 |
| Lejour, M | 1 |
| Hornstein, OP | 1 |
| Knickenberg, M | 1 |
| Reeves, JE | 1 |
| Leumann, EP | 1 |
| Bauer, RP | 1 |
| Slaton, PE | 1 |
| Biglieri, EG | 1 |
| Holliday, MA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| First Clinical Study of Erbium-YAG Laser Vaporisation of Cutaneous Neurofibromas[NCT00921037] | Phase 2/Phase 3 | 12 participants (Anticipated) | Interventional | 2006-04-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
25 other studies available for salicylic acid and Neurofibromatosis 1
| Article | Year |
|---|---|
Double Head: Giant Solitary Occipital Scalp Plexiform Neurofibroma Without Neurofibromatosis.
Topics: Adolescent; Humans; Male; Neoplasm Recurrence, Local; Neurofibroma; Neurofibroma, Plexiform; Neurofi | 2022 |
[Management of cervico-cephalic plexiform neurofibromas: About 35 cases].
Topics: Adult; Female; Humans; Male; Neurofibroma, Plexiform; Neurofibromatosis 1; Retrospective Studies; Sc | 2020 |
Congenital giant plexiform neurofibroma with occipital calvarial dysplasia in association with meningoencephalocele in neurofibromatosis Type 1 and segmental neurofibromatosis: report of 2 cases.
Topics: Adolescent; Bone Diseases, Developmental; Encephalocele; Humans; Magnetic Resonance Imaging; Male; M | 2013 |
Quantitative associations of scalp and body subcutaneous neurofibromas with internal plexiform tumors in neurofibromatosis 1.
Topics: Humans; Neurofibroma, Plexiform; Neurofibromatosis 1; Odds Ratio; Scalp; Skin Neoplasms; Subcutaneou | 2015 |
[A case of neurofibromatosis-1 in which severe bleeding was observed from a neurofibroma under the scalp].
Topics: Hematoma; Humans; Male; Neurofibromatosis 1; Scalp; Young Adult | 2010 |
Undifferentiated pleomorphic sarcoma in a child with type 1 neurofibromatosis.
Topics: Child; Female; Head and Neck Neoplasms; Humans; Neurofibromatosis 1; Sarcoma; Scalp; Skin Neoplasms; | 2010 |
Diffuse scalp malignant peripheral nerve sheath tumor with intracranial extension in a patient with neurofibromatosis type 1.
Topics: Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Invasiveness; Neurofibromatosis 1; N | 2010 |
Scalp neurofibromas associated with bone dysplasia.
Topics: Adult; Bone Diseases, Developmental; Comorbidity; Female; Humans; Magnetic Resonance Imaging; Male; | 2011 |
Cerebrovasculopathy in NF1 associated with ocular and scalp defects.
Topics: Anterior Eye Segment; Cerebral Angiography; Corneal Opacity; Cytogenetic Analysis; Eye Abnormalities | 2011 |
Subcutaneous tumor seeding after biopsy in gliomatosis cerebri.
Topics: Adult; Biopsy; Brain Neoplasms; Female; Humans; Neoplasm Grading; Neoplasm Seeding; Neoplasms, Neuro | 2012 |
Massive scalp hematoma due to diffuse neurofibroma in NF-1.
Topics: Biopsy; Drainage; Hematoma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Necrosis; Neurofi | 2013 |
Giant malignant peripheral nerve sheath tumor of the scalp.
Topics: Female; Humans; Middle Aged; Nerve Sheath Neoplasms; Neurofibromatosis 1; S100 Proteins; Scalp | 2012 |
Rapid expansion of benign scalp neurofibroma caused by massive intratumoral hemorrhage--case report.
Topics: Hemorrhage; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neurofibromatosis 1; Scalp; Skin | 2002 |
[Scalp neurofibrosarcoma of a von Recklinghausen's disease patient].
Topics: Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neurofibromatosis 1; Neurofibrosarcoma; Scalp | 2002 |
[Large bilateral lung opacities].
Topics: Adult; Biopsy; Chest Pain; Comorbidity; Female; Functional Laterality; Humans; Leiomyosarcoma; Lung | 2005 |
[Combination of intravascular surgery and surgical operation for occipital subcutaneous arteriovenous fistula in a patient with neurofibromatosis type I].
Topics: Adult; Arteriovenous Fistula; Carotid Artery, External; Embolization, Therapeutic; Hemorrhage; Human | 2002 |
[Dermo-neuro-hypsarrhythmia. Association of a congenital dermatosis and hypsarthymia. 9 cases (author's transl)].
Topics: Abnormalities, Multiple; Adrenocorticotropic Hormone; Child, Preschool; Electroencephalography; Fema | 1977 |
Use of the carbon dioxide laser in treating multiple cutaneous neurofibromas.
Topics: Adult; Carbon Dioxide; Eyelid Neoplasms; Facial Neoplasms; Female; Foot Diseases; Humans; Laser Ther | 1991 |
[Cutis verticis gyrata].
Topics: Acromegaly; Adult; Humans; Hypertrophy; Male; Neurofibromatosis 1; Scalp; Scalp Dermatoses; Skin Neo | 1990 |
Segmental neurofibromatosis.
Topics: Aged; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neurofibromatosis 1; Scalp; Ski | 1990 |
Occipital scalp nodules in a neonate.
Topics: Female; Humans; Infant, Newborn; Neurofibromatosis 1; Scalp; Skin Neoplasms; Tomography, X-Ray Compu | 1990 |
[Neurofibromatosis of the scalp associated with occipital bone aplasia].
Topics: Adult; Humans; Male; Neurofibromatosis 1; Occipital Bone; Scalp; Skin Neoplasms | 1986 |
[On the Schimmelpenning-Feuerstein-Mims-syndrome (Organoid Nevus-Phakomatosis) (author's transl)].
Topics: Child; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Neurofibromatosis 1; Nevus, Pigment | 1974 |
Neurofibromatosis of the scalp.
Topics: Child, Preschool; Humans; Male; Neurofibromatosis 1; Scalp | 1969 |
Renovascular hypertension in children.
Topics: Adolescent; Aldosterone; Angiography; Blood Chemical Analysis; Child; Humans; Hyperaldosteronism; Hy | 1970 |