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salicylic acid and Neurofibromatosis 1

salicylic acid has been researched along with Neurofibromatosis 1 in 25 studies

Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).

Neurofibromatosis 1: An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).

Research Excerpts

ExcerptRelevanceReference
"Plexiform neurofibroma is a characteristic lesion of Von Recklinghausen's disease."1.56[Management of cervico-cephalic plexiform neurofibromas: About 35 cases]. ( Foba, ML; Ndiaye, AÏ; Ndiaye, L; Sankalé, AA, 2020)
"Internal plexiform neurofibromas are a major cause of adverse outcomes in patients with neurofibromatosis 1 (NF1)."1.42Quantitative associations of scalp and body subcutaneous neurofibromas with internal plexiform tumors in neurofibromatosis 1. ( Arman, D; Birch, P; Chohan, H; Farschtschi, S; Friedman, JM; Fuensterer, C; Jett, K; Kluwe, L; Mautner, VF; Nguyen, R, 2015)
"The first case had an associated meningoencephalocele, and the second had large vascular channels within the lesion and the dominant ipsilateral transverse sinus lying in the center of the calvarial defect."1.39Congenital giant plexiform neurofibroma with occipital calvarial dysplasia in association with meningoencephalocele in neurofibromatosis Type 1 and segmental neurofibromatosis: report of 2 cases. ( Dadlani, R; Ghosal, N; Hegde, AS; Sadanand, V, 2013)
"These characteristics confirmed gliomatosis cerebri."1.38Subcutaneous tumor seeding after biopsy in gliomatosis cerebri. ( Buis, DR; De Witt Hamer, PC; van der Valk, P, 2012)
"Malignant peripheral nerve sheath tumors (MPNST) constitute a group of soft tissue neoplasms with neurogenic origin."1.38Giant malignant peripheral nerve sheath tumor of the scalp. ( A M M, A; B A, de L; F, T; G H T S, B; H, C; R C, L; T C C, C, 2012)
"The association of Von Recklinghausen's disease and soft tissue sarcoma is rare: most often neurofibroma which degenerates is observed."1.33[Large bilateral lung opacities]. ( Abdelghani, A; Benzarti, M; Garrouche, A; Hayouni, A; Jerray, M; Mezghani, S; Trabelsi, A, 2005)
"A 62-year-old man with neurofibromatosis type 1 presented with rapid growth of a scalp mass."1.31Rapid expansion of benign scalp neurofibroma caused by massive intratumoral hemorrhage--case report. ( Haraoka, S; Kazekawa, K; Nii, K; Nomoto, Y; Tanaka, A; Tsutsumi, M; Ueno, Y, 2002)
"We presented a case of neurofibromatosis type I (NF-1) associated with an extracranial arteriovenous fistula (AVF) fed by the occipital and vertebral artery."1.31[Combination of intravascular surgery and surgical operation for occipital subcutaneous arteriovenous fistula in a patient with neurofibromatosis type I]. ( Abe, T; Hasegawa, Y; Hayashi, J; Kanki, T; Tanaka, T; Ui, K; Usami, S, 2002)
"These 9 cases confirm that tuberose sclerosis, von Recklinghausen's neurofibromatosis, incontinentia pigmenti, linear warty sebaceous naevus and alopecic naevus resulting in a woolly naevus of the scalp may be complicated by flexion spasms with hypsarhythmia."1.26[Dermo-neuro-hypsarrhythmia. Association of a congenital dermatosis and hypsarthymia. 9 cases (author's transl)]. ( Beauvais, P; Bressieux, JM; Larrègue, M; Lauret, P, 1977)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19905 (20.00)18.7374
1990's4 (16.00)18.2507
2000's4 (16.00)29.6817
2010's10 (40.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Baldawa, S1
Chimanchode, G1
Vora, N1
Ndiaye, L1
Ndiaye, AÏ1
Foba, ML1
Sankalé, AA1
Dadlani, R1
Sadanand, V1
Ghosal, N1
Hegde, AS1
Jett, K2
Nguyen, R1
Arman, D1
Birch, P1
Chohan, H1
Farschtschi, S1
Fuensterer, C1
Kluwe, L1
Friedman, JM2
Mautner, VF1
Yunoki, M1
Hiramatsu, M1
Hirashita, K1
Gohda, Y1
Yoshino, K1
Fujimoto, S1
Tanaka, H1
Mizobuchi, K1
Takata, K1
Morito, T1
Patel, RR1
Meehan, S1
Orlow, SJ1
Ge, P1
Fu, S1
Lu, L1
Zhong, Y1
Qi, B1
Luo, Y1
Nemeur, A1
Combemale, P1
Souteyrand, P1
D'Incan, M1
Smith, M1
Heran, MK1
Connolly, MB1
Heran, HK1
Lyons, CJ1
Steinbok, P1
Armstrong, L1
Buis, DR1
van der Valk, P1
De Witt Hamer, PC1
Bhaskar, S1
Sobti, S1
Singh, AK1
F, T1
A M M, A1
B A, de L1
T C C, C1
R C, L1
G H T S, B1
H, C1
Tsutsumi, M1
Kazekawa, K1
Tanaka, A1
Ueno, Y1
Nomoto, Y1
Nii, K1
Haraoka, S1
Niijima, K1
Mezghani, S1
Abdelghani, A1
Trabelsi, A1
Hayouni, A1
Garrouche, A1
Benzarti, M1
Jerray, M1
Tanaka, T1
Hasegawa, Y1
Kanki, T1
Hayashi, J1
Ui, K1
Usami, S1
Abe, T1
Larrègue, M1
Lauret, P1
Beauvais, P1
Bressieux, JM1
Becker, DW1
Fesel, R1
Plewig, G1
Lentrodt, J1
Trattner, A1
David, M1
Hodak, E1
Ben-David, E1
Sandbank, M1
Koransky, J1
Duchateau, J1
Lejour, M1
Hornstein, OP1
Knickenberg, M1
Reeves, JE1
Leumann, EP1
Bauer, RP1
Slaton, PE1
Biglieri, EG1
Holliday, MA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
First Clinical Study of Erbium-YAG Laser Vaporisation of Cutaneous Neurofibromas[NCT00921037]Phase 2/Phase 312 participants (Anticipated)Interventional2006-04-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

25 other studies available for salicylic acid and Neurofibromatosis 1

ArticleYear
Double Head: Giant Solitary Occipital Scalp Plexiform Neurofibroma Without Neurofibromatosis.
    World neurosurgery, 2022, Volume: 159

    Topics: Adolescent; Humans; Male; Neoplasm Recurrence, Local; Neurofibroma; Neurofibroma, Plexiform; Neurofi

2022
[Management of cervico-cephalic plexiform neurofibromas: About 35 cases].
    Annales de chirurgie plastique et esthetique, 2020, Volume: 65, Issue:4

    Topics: Adult; Female; Humans; Male; Neurofibroma, Plexiform; Neurofibromatosis 1; Retrospective Studies; Sc

2020
Congenital giant plexiform neurofibroma with occipital calvarial dysplasia in association with meningoencephalocele in neurofibromatosis Type 1 and segmental neurofibromatosis: report of 2 cases.
    Journal of neurosurgery. Pediatrics, 2013, Volume: 12, Issue:5

    Topics: Adolescent; Bone Diseases, Developmental; Encephalocele; Humans; Magnetic Resonance Imaging; Male; M

2013
Quantitative associations of scalp and body subcutaneous neurofibromas with internal plexiform tumors in neurofibromatosis 1.
    American journal of medical genetics. Part A, 2015, Volume: 167, Issue:7

    Topics: Humans; Neurofibroma, Plexiform; Neurofibromatosis 1; Odds Ratio; Scalp; Skin Neoplasms; Subcutaneou

2015
[A case of neurofibromatosis-1 in which severe bleeding was observed from a neurofibroma under the scalp].
    No shinkei geka. Neurological surgery, 2010, Volume: 38, Issue:3

    Topics: Hematoma; Humans; Male; Neurofibromatosis 1; Scalp; Young Adult

2010
Undifferentiated pleomorphic sarcoma in a child with type 1 neurofibromatosis.
    The British journal of dermatology, 2010, Volume: 163, Issue:2

    Topics: Child; Female; Head and Neck Neoplasms; Humans; Neurofibromatosis 1; Sarcoma; Scalp; Skin Neoplasms;

2010
Diffuse scalp malignant peripheral nerve sheath tumor with intracranial extension in a patient with neurofibromatosis type 1.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010, Volume: 17, Issue:11

    Topics: Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Invasiveness; Neurofibromatosis 1; N

2010
Scalp neurofibromas associated with bone dysplasia.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2011, Volume: 25, Issue:10

    Topics: Adult; Bone Diseases, Developmental; Comorbidity; Female; Humans; Magnetic Resonance Imaging; Male;

2011
Cerebrovasculopathy in NF1 associated with ocular and scalp defects.
    American journal of medical genetics. Part A, 2011, Volume: 155A, Issue:2

    Topics: Anterior Eye Segment; Cerebral Angiography; Corneal Opacity; Cytogenetic Analysis; Eye Abnormalities

2011
Subcutaneous tumor seeding after biopsy in gliomatosis cerebri.
    Journal of neuro-oncology, 2012, Volume: 106, Issue:2

    Topics: Adult; Biopsy; Brain Neoplasms; Female; Humans; Neoplasm Grading; Neoplasm Seeding; Neoplasms, Neuro

2012
Massive scalp hematoma due to diffuse neurofibroma in NF-1.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:4

    Topics: Biopsy; Drainage; Hematoma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Necrosis; Neurofi

2013
Giant malignant peripheral nerve sheath tumor of the scalp.
    Acta neurologica Taiwanica, 2012, Volume: 21, Issue:3

    Topics: Female; Humans; Middle Aged; Nerve Sheath Neoplasms; Neurofibromatosis 1; S100 Proteins; Scalp

2012
Rapid expansion of benign scalp neurofibroma caused by massive intratumoral hemorrhage--case report.
    Neurologia medico-chirurgica, 2002, Volume: 42, Issue:8

    Topics: Hemorrhage; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neurofibromatosis 1; Scalp; Skin

2002
[Scalp neurofibrosarcoma of a von Recklinghausen's disease patient].
    No to shinkei = Brain and nerve, 2002, Volume: 54, Issue:8

    Topics: Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neurofibromatosis 1; Neurofibrosarcoma; Scalp

2002
[Large bilateral lung opacities].
    Revue de pneumologie clinique, 2005, Volume: 61, Issue:6

    Topics: Adult; Biopsy; Chest Pain; Comorbidity; Female; Functional Laterality; Humans; Leiomyosarcoma; Lung

2005
[Combination of intravascular surgery and surgical operation for occipital subcutaneous arteriovenous fistula in a patient with neurofibromatosis type I].
    No shinkei geka. Neurological surgery, 2002, Volume: 30, Issue:3

    Topics: Adult; Arteriovenous Fistula; Carotid Artery, External; Embolization, Therapeutic; Hemorrhage; Human

2002
[Dermo-neuro-hypsarrhythmia. Association of a congenital dermatosis and hypsarthymia. 9 cases (author's transl)].
    Annales de dermatologie et de venereologie, 1977, Volume: 104, Issue:1

    Topics: Abnormalities, Multiple; Adrenocorticotropic Hormone; Child, Preschool; Electroencephalography; Fema

1977
Use of the carbon dioxide laser in treating multiple cutaneous neurofibromas.
    Annals of plastic surgery, 1991, Volume: 26, Issue:6

    Topics: Adult; Carbon Dioxide; Eyelid Neoplasms; Facial Neoplasms; Female; Foot Diseases; Humans; Laser Ther

1991
[Cutis verticis gyrata].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1990, Volume: 41, Issue:9

    Topics: Acromegaly; Adult; Humans; Hypertrophy; Male; Neurofibromatosis 1; Scalp; Scalp Dermatoses; Skin Neo

1990
Segmental neurofibromatosis.
    Journal of the American Academy of Dermatology, 1990, Volume: 23, Issue:5 Pt 1

    Topics: Aged; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neurofibromatosis 1; Scalp; Ski

1990
Occipital scalp nodules in a neonate.
    Pediatric dermatology, 1990, Volume: 7, Issue:4

    Topics: Female; Humans; Infant, Newborn; Neurofibromatosis 1; Scalp; Skin Neoplasms; Tomography, X-Ray Compu

1990
[Neurofibromatosis of the scalp associated with occipital bone aplasia].
    Annales de chirurgie plastique et esthetique, 1986, Volume: 31, Issue:1

    Topics: Adult; Humans; Male; Neurofibromatosis 1; Occipital Bone; Scalp; Skin Neoplasms

1986
[On the Schimmelpenning-Feuerstein-Mims-syndrome (Organoid Nevus-Phakomatosis) (author's transl)].
    Archiv fur dermatologische Forschung, 1974, Jul-01, Volume: 250, Issue:1

    Topics: Child; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Neurofibromatosis 1; Nevus, Pigment

1974
Neurofibromatosis of the scalp.
    Arizona medicine, 1969, Volume: 26, Issue:8

    Topics: Child, Preschool; Humans; Male; Neurofibromatosis 1; Scalp

1969
Renovascular hypertension in children.
    Pediatrics, 1970, Volume: 46, Issue:3

    Topics: Adolescent; Aldosterone; Angiography; Blood Chemical Analysis; Child; Humans; Hyperaldosteronism; Hy

1970