salicylic acid has been researched along with Insulin Resistance in 8 studies
Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated whether diosgenin, a widely used steroidal sapogenin, exerted protection against palmitate (PA)-induced inflammation and insulin resistance in the endothelium." | 7.78 | Diosgenin ameliorates palmitate-induced endothelial dysfunction and insulin resistance via blocking IKKβ and IRS-1 pathways. ( Gao, X; Huang, F; Kou, J; Liu, B; Liu, K; Zhao, W, 2012) |
| "Salicylic acid pretreatment completely reversed the effects of PMA and TNFalpha on both Akt and IRS1." | 5.32 | Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells. ( Dallas-Yang, Q; Jiang, G; Liu, F; Moller, DE; Zhang, BB, 2003) |
| "We investigated whether diosgenin, a widely used steroidal sapogenin, exerted protection against palmitate (PA)-induced inflammation and insulin resistance in the endothelium." | 3.78 | Diosgenin ameliorates palmitate-induced endothelial dysfunction and insulin resistance via blocking IKKβ and IRS-1 pathways. ( Gao, X; Huang, F; Kou, J; Liu, B; Liu, K; Zhao, W, 2012) |
| " Tumor necrosis factor (TNF)-alpha caused insulin resistance on glucose uptake and GLUT4 translocation by impairing insulin stimulation of insulin receptor (IR) and IR substrate (IRS)-1 and IRS-2 tyrosine phosphorylation, IRS-associated phosphatidylinositol 3-kinase activation, and Akt phosphorylation." | 3.72 | Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner. ( de Alvaro, C; Hernandez, R; Lorenzo, M; Teruel, T, 2004) |
| "Information about the chemical constituents of SJHK were collected, and druggable compounds were screened based on oral bioavailability and drug-likeness." | 1.72 | Network pharmacology and molecular docking approaches to elucidate the potential compounds and targets of Saeng-Ji-Hwang-Ko for treatment of type 2 diabetes mellitus. ( Ahn, D; Chung, SJ; Jeong, S; Kim, H; Kim, HH; Kim, Y; Ko, M, 2022) |
| "Salicylic acid pretreatment completely reversed the effects of PMA and TNFalpha on both Akt and IRS1." | 1.32 | Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells. ( Dallas-Yang, Q; Jiang, G; Liu, F; Moller, DE; Zhang, BB, 2003) |
| "Insulin resistance is a major factor in the pathogenesis of type 2 diabetes and may involve fat-induced activation of a serine kinase cascade involving IKK-beta." | 1.31 | Prevention of fat-induced insulin resistance by salicylate. ( Chen, Y; Fillmore, JJ; Karin, M; Kim, JK; Kim, YJ; Lee, J; Li, ZW; Moore, I; Perret, P; Shoelson, SE; Shulman, GI; Yuan, M, 2001) |
| "This syndrome is characterized by obesity, mild mental retardation, delayed puberty, acanthosis nigricans and hyperinsulinaemia." | 1.31 | Cutis verticis gyrata of the scalp in a patient with autosomal dominant insulin resistance syndrome. ( Black, MM; Brenton, DP; Darley, CR; Lee, PJ; Sonksen, PH; Woollons, A, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ko, M | 1 |
| Kim, Y | 1 |
| Kim, HH | 1 |
| Jeong, S | 1 |
| Ahn, D | 1 |
| Chung, SJ | 1 |
| Kim, H | 1 |
| Liu, K | 1 |
| Zhao, W | 1 |
| Gao, X | 1 |
| Huang, F | 1 |
| Kou, J | 1 |
| Liu, B | 1 |
| Ismail, WI | 1 |
| King, JA | 1 |
| Anwar, K | 1 |
| Pillay, TS | 1 |
| Jiang, G | 1 |
| Dallas-Yang, Q | 1 |
| Liu, F | 1 |
| Moller, DE | 1 |
| Zhang, BB | 1 |
| de Alvaro, C | 1 |
| Teruel, T | 1 |
| Hernandez, R | 1 |
| Lorenzo, M | 1 |
| Kim, JK | 1 |
| Kim, YJ | 1 |
| Fillmore, JJ | 1 |
| Chen, Y | 1 |
| Moore, I | 1 |
| Lee, J | 1 |
| Yuan, M | 1 |
| Li, ZW | 1 |
| Karin, M | 1 |
| Perret, P | 1 |
| Shoelson, SE | 1 |
| Shulman, GI | 1 |
| Serarslan, G | 1 |
| Özcan, O | 1 |
| Okyay, E | 1 |
| Ünlü, B | 1 |
| Karadağ, M | 1 |
| Woollons, A | 1 |
| Darley, CR | 1 |
| Lee, PJ | 1 |
| Brenton, DP | 1 |
| Sonksen, PH | 1 |
| Black, MM | 1 |
8 other studies available for salicylic acid and Insulin Resistance
| Article | Year |
|---|---|
Network pharmacology and molecular docking approaches to elucidate the potential compounds and targets of Saeng-Ji-Hwang-Ko for treatment of type 2 diabetes mellitus.
Topics: Cyclooxygenase 2; Diabetes Mellitus, Type 2; Drugs, Chinese Herbal; Estrogens; Estrone; Humans; Insu | 2022 |
Diosgenin ameliorates palmitate-induced endothelial dysfunction and insulin resistance via blocking IKKβ and IRS-1 pathways.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cells, Cultured; Diosgenin; Dose-Response Rela | 2012 |
Indinavir and nelfinavir inhibit proximal insulin receptor signaling and salicylate abrogates inhibition: potential role of the NFkappa B pathway.
Topics: 3T3-L1 Cells; Adaptor Proteins, Signal Transducing; Animals; Anti-Infective Agents; CHO Cells; Crice | 2013 |
Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells.
Topics: Animals; Anthracenes; Cell Line; Enzyme Activation; Humans; I-kappa B Kinase; Insulin Receptor Subst | 2003 |
Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner.
Topics: Animals; Biological Transport; Blotting, Western; Cell Membrane; Cells, Cultured; Enzyme Activation; | 2004 |
Prevention of fat-induced insulin resistance by salicylate.
Topics: Animals; Diabetes Mellitus, Type 2; Dietary Fats; Enzyme Inhibitors; Glucose; Glucose Clamp Techniqu | 2001 |
Role of adiponectin and leptin in patients with alopecia areata with scalp hair loss.
Topics: Adiponectin; Alopecia Areata; Body Mass Index; Case-Control Studies; Female; Humans; Insulin Resista | 2021 |
Cutis verticis gyrata of the scalp in a patient with autosomal dominant insulin resistance syndrome.
Topics: Adult; Biopsy; Female; Humans; Hyperinsulinism; Insulin Resistance; Scalp; Scalp Dermatoses; Syndrom | 2000 |